Dense Residual Network-Powered Early Detection of Cardiovascular Diseases Using Multimodal Medical Imaging
DOI:
https://doi.org/10.52783/jns.v14.2221Keywords:
Deep learning, Dense Residual Network, Multimodal medical imaging, Cardiovascular disease detection, Early diagnosisAbstract
Cardiovascular diseases (CVDs) remain a leading cause of mortality worldwide, necessitating early and precise detection to improve patient outcomes. Traditional diagnostic approaches rely on single-modal imaging, which often lacks the depth required for accurate prognostics. The integration of multimodal medical imaging enhances diagnostic accuracy by leveraging complementary information from multiple imaging techniques, such as MRI, CT, and echocardiography. However, effectively processing and analyzing this high-dimensional data remains a significant challenge. To address this, a Dense Residual Network (DenseResNet)-powered deep learning model is proposed for early CVD detection. The method employs multimodal feature fusion to extract relevant spatial and temporal features, enabling comprehensive disease identification. The DenseResNet architecture, with its densely connected residual blocks, enhances gradient flow and prevents vanishing gradients, thereby improving model stability and convergence. The proposed approach undergoes rigorous training and validation using a dataset comprising multimodal cardiac images. Experimental results demonstrate superior performance compared to conventional deep learning models, achieving an accuracy of 98.4%, sensitivity of 97.8%, and specificity of 98.1% in CVD classification.
Downloads
Metrics
References
Papanastasiou, G., Dikaios, N., Huang, J., Wang, C., & Yang, G. (2023). Is attention all you need in medical image analysis? A review. IEEE Journal of Biomedical and Health Informatics, 28(3), 1398-1411.
Mamo, A. A., Gebresilassie, B. G., Mukherjee, A., Hassija, V., & Chamola, V. (2024). Advancing Medical Imaging Through Generative Adversarial Networks: A Comprehensive Review and Future Prospects. Cognitive Computation, 16(5), 2131-2153.
Zhang, N., Yang, G., Gao, Z., Xu, C., Zhang, Y., Shi, R., ... & Firmin, D. (2019). Deep learning for diagnosis of chronic myocardial infarction on nonenhanced cardiac cine MRI. Radiology, 291(3), 606-617.
Lei, Y., Niu, C., Zhang, J., Wang, G., & Shan, H. (2023). CT image denoising and deblurring with deep learning: current status and perspectives. IEEE Transactions on Radiation and Plasma Medical Sciences, 8(2), 153-172.
Yang, G., Lv, J., Chen, Y., Huang, J., & Zhu, J. (2022). Generative Adversarial Network Powered Fast Magnetic Resonance Imaging—Comparative Study and New Perspectives. In Generative Adversarial Learning: Architectures and Applications (pp. 305-339). Cham: Springer International Publishing.
Sheela, K. S., Justus, V., Asaad, R. R., & Kumar, R. L. (2025). Enhancing liver tumor segmentation with UNet-ResNet: Leveraging ResNet’s power. Technology and Health Care, 33(1), 1-15.
Chaudhary, M. F., Gerard, S. E., Christensen, G. E., Cooper, C. B., Schroeder, J. D., Hoffman, E. A., & Reinhardt, J. M. (2024). LungViT: Ensembling cascade of texture sensitive hierarchical vision transformers for cross-volume chest CT image-to-image translation. IEEE transactions on medical imaging.
Chen, X., Xie, H., Tao, X., Xu, L., Wang, J., Dai, H. N., & Wang, F. L. (2024). A topic modeling‐based bibliometric exploration of automatic summarization research. Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery, 14(5), e1540.
Milosevic, M., Jin, Q., Singh, A., & Amal, S. (2024). Applications of AI in multi-modal imaging for cardiovascular disease. Frontiers in radiology, 3, 1294068.
Shiwlani, A., Ahmad, A., Umar, M., Dharejo, N., Tahir, A., & Shiwlani, S. (2024). Analysis of multi-modal data through deep learning techniques to diagnose CVDs: A review. International Journal, 11(1), 402-420.
Sun, X., Guan, S., Wu, L., Zhang, T., & Ying, L. (2025). A multimodal deep learning framework for automated major adverse cardiovascular events prediction in patients with end-stage renal disease integrating clinical and cardiac MRI data. Displays, 102998.
Bullock-Palmer, R. P., Flores Rosario, K., Douglas, P. S., Hahn, R. T., Lang, R. M., Chareonthaitawee, P., ... & Daubert, M. A. (2024). Multimodality cardiac imaging and the imaging workforce in the United States: diversity, disparities, and future directions. Circulation: Cardiovascular Imaging, 17(2), e016409.
Wang, Y. R., Yang, K., Wen, Y., Wang, P., Hu, Y., Lai, Y., ... & Zhao, S. (2024). Screening and diagnosis of cardiovascular disease using artificial intelligence-enabled cardiac magnetic resonance imaging. Nature Medicine, 30(5), 1471-1480.
Zhu, J., Liu, H., Liu, X., Chen, C., & Shu, M. (2025). Cardiovascular disease detection based on deep learning and multi-modal data fusion. Biomedical Signal Processing and Control, 99, 106882.
Saha, P., De, A., Roy, S. D., & Bhowmik, M. K. (2024). A comprehensive review on deep cardiovascular disease detection approaches: its datasets, image modalities and methods. Multimedia Tools and Applications, 1-47.
Paul, S., & Jain, S. (2024). A Novel Detection of Cerebrovascular Disease using Multimodal Medical Image Fusion. Recent Advances in Inflammation & Allergy Drug Discovery, 18(2), 140-155.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

