Dosimetric Comparison Between Intensity Modulated Radiotherapy and Volumetric-Modulated Arc Therapy Radiotherapy in Hypofractionation Bladder Preservation

Authors

  • Radwa Abdel Maksoud Mostafa
  • Medhat El Sebaei
  • Mohamed Saad Zaghloul
  • Shreif Abdel Karim
  • Dina Mohamed Abdelaziz

Keywords:

VMAT, IMRT, Dosimetric study, bladder preservation, Urothelial cancer

Abstract


ABSTRACT

Objective:    To    compare    the    intensity-modulated radiotherapy (IMRT) 11-field technique to Volumetric-modulated arc therapy (VMAT) for   bladder preservation hypofractionated radical radiotherapy in   high-risk   urothelial   bladder   cancer   cases.

Patients and Methods:  A dosimetric analysis of 10 urothelial bladder cancer patients who underwent   maximum transuretheralbaldder resection (TURBT) followed by   bladder preservation using hypofractionation. These   patients   were   presented   to   the   radiotherapy   department, National   Cancer   Institute, Cairo, between   2018   and   2020   with radical radiotherapy using the IMRT technique.  Two plans were designed for each patient, one using 11-field IMRT and the second using Rapid arc.  The two techniques were compared, including the PTV, bowel bag, rectum and both femoral heads, also treatment time.

Results: Comparing different DVHs, the planning target volume (PTV) was   adequately   covered   in   both   plans, while   the   11-field   IMRT technique delivered significantly lower monitor unit and treatment time and better homogeneity index and conformity index. 

Conclusion: The results of the comparison between IMRT and VMAT show that VMAT is superior to IMRT in terms of homogeneity and conformity and treatment time.

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Published

2025-05-12

How to Cite

1.
Abdel Maksoud Mostafa R, El Sebaei M, Saad Zaghloul M, Abdel Karim S, Mohamed Abdelaziz D. Dosimetric Comparison Between Intensity Modulated Radiotherapy and Volumetric-Modulated Arc Therapy Radiotherapy in Hypofractionation Bladder Preservation. J Neonatal Surg [Internet]. 2025May12 [cited 2025Dec.7];14(21S):1188-92. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/5670

Issue

Vol. 14 No. 21S (2025): Journal of Neonatal Surgery

Section

Original Article

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