Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy

Authors

  • Ian Munro Rogers Adjunct faculty AIMST University malaysia

DOI:

https://doi.org/10.47338/jns.v11.1004

Keywords:

Etiology, Pyloric stenosis of infancy, Neonate, Hypergastrinemia, Hyperacidity, Gastrin

Abstract

The early observations of those who first described babies with pyloric stenosis (PS) are used as a backdrop for the development of the Inherited Primary Hyperacidity theory of cause. Those early truths, uncomplicated by modern technology, have acted as a springboard for pathogenesis. Hyperacidity, male predominance, family history, self-cure, enhanced appetite, and time-sensitive presentation were all well known to the early pioneers. Any system of pathogenesis must explain all these clinical features. The Inherited Primary Hyperacidity theory does this and is a credible explanation for all the clinical features established by these early pioneers. The evidence which supports a delay in maturation of the negative feedback between gastrin and gastric acidity is presented. Such a phenomenon further supports the Primary Hyperacidity theory.

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References

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Published

2022-01-14

How to Cite

1.
Rogers IM. Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy. J Neonatal Surg [Internet]. 2022Jan.14 [cited 2022Jan.22];11:7. Available from: https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/1004

Issue

Section

Short Communication