Congenital pyloric atresia with epidermolysis bullosa: A case series


  • Shishir Kumar RIMS, Ranchi
  • Vivek Manchanda Department of Pediatric Surgery, Chacha Nehru Bal Chikitsalya, New Delhi-110031, India.
  • Parveen Kumar Department of Pediatric Surgery, Chacha Nehru Bal Chikitsalya, New Delhi-110031, India.
  • Rohit H Bhandari Ex-senior resident, Department of Anaesthesia, Chacha Nehru Bal Chikitsalya, New Delhi-110031



Neonate, Gastric outlet obstruction, Carmi syndrome, Pyloroplasty


Background: Carmi syndrome is the name given to the association of congenital pyloric atresia and epidermolysis bullosa. It has a high mortality.

Case series: We report 3 neonates with features of multiple skin blisters and a classical X-ray picture of a single bubble appearance. Two of them underwent surgery while 1 succumbed to sepsis in the pre-operative period. One baby had delayed mortality and the other is doing well in follow-up.

Conclusions: Carmi syndrome should be kept as a differential diagnosis in neonates with skin blisters and feed intolerance. Early recognition with prompt medical and surgical management may contribute to a successful outcome.


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How to Cite

Kumar S, Manchanda V, Kumar P, Bhandari RH. Congenital pyloric atresia with epidermolysis bullosa: A case series. J Neonatal Surg [Internet]. 2022Nov.6 [cited 2022Dec.3];11:30. Available from:

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