Iatrogenic esophageal perforation in infants: How to avoid thoracotomy? A case series


  • Riccardo Rizzo Fondazione Policlinico Universitario "A.Gemelli" IRCCS
  • Filomena Valentina Paradiso Pediatric Surgery Department, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy
  • Sara Silvaroli Pediatric Surgery Department, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy
  • Lorenzo Nanni Pediatric Surgery Department, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy




Esophageal perforation , Prematurity, Neonate


Background: Esophageal perforation is uncommon and often iatrogenic in the neonatal period, with premature and low birth weight infants (<1500 g) being particularly susceptible. It usually occurs at the pharyngoesophageal junction and can be confused with esophageal atresia due to respiratory signs and excessive salivation. Diagnostic evaluation and treatment are still debated.

Case Presentation: Two neonatal cases of iatrogenic esophageal perforation are described. The suspected diagnosis was confirmed only with thoracotomy. Diagnostic difficulties  and therapeutic modalities are discussed.

Conclusion: These two cases show the importance of the clinical clues (anamnesis and clinical findings) to suspect the diagnosis of esophageal perforation.


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How to Cite

Rizzo R, Paradiso FV, Silvaroli S, Nanni L. Iatrogenic esophageal perforation in infants: How to avoid thoracotomy? A case series. J Neonatal Surg [Internet]. 2023Jun.9 [cited 2024Feb.22];12:18. Available from: https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/1181