Cystic hygroma and esophageal atresia with tracheoesophageal fistula: Is there a genetic association?

Authors

DOI:

https://doi.org/10.47338/jns.v10.997

Keywords:

Tracheoesophageal fistula, Cystic hygroma, Fox gene complex

Abstract

Background: Tracheoesophageal fistula (TEF) is associated with many other congenital anomalies like cardiac, renal, and vertebral, but the association with cystic hygroma is very rare.

Case Presentation: We report a neonate, antenatally diagnosed with cystic hygroma of the neck and incidentally diagnosed to have TEF. The baby was operated on after adequate stabilization and the cystic hygroma was managed with injection sclerotherapy. The genetic analysis for the FOX genes complex has been done in this case and the results showed no association between the two.

Conclusion: There is a need for future studies to find out if the association between cystic hygroma and TEF is by chance or if any embryological or genetic cause can be attributed to it.

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Author Biographies

Sravanthi Vutukuru

Senior Resident

Department of Pediatric Surgery

Post Graduate Institute of Medical Education and Research

India

Nitin James Peters, Post Graduate Institute of Medical Education and Research, Chandigarh

Associate Professor of Pediatric Surgery, Advanced Pediatrics CenterPGIMER, Chandigarh India

Shivani Dogra

Assistant Professor

Department of Pediatric Surgery

Post Graduate Institute of Medical Education and Research

Chandigarh

India

160012

Ram Samujh

Professor and Head

Department of Pediatric Surgery

Post Graduate Institute of Medical Education and Research

Chandigarh

India

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Published

2021-09-12

How to Cite

1.
Vutukuru S, Peters NJ, Dogra S, Samujh R. Cystic hygroma and esophageal atresia with tracheoesophageal fistula: Is there a genetic association?. J Neonatal Surg [Internet]. 2021Sep.12 [cited 2021Dec.2];10:42. Available from: https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/997