A Novel approach to multi-level image classification of Retinal Diseases

Authors

  • Patel Vandanabahen Gopalbhai
  • Jayesh N. Modi

DOI:

https://doi.org/10.52783/jns.v14.1913

Keywords:

Retinal Diseases, Multi-Level Image Classification, Deep Learning, Convolutional Neural Networks, Medical Image Analysis

Abstract

Diseases of the retina, like diabetic retinopathy, age-related macular degeneration, and glaucoma, are major causes of vision loss and blindness around the world. Early identification and labelling of these illnesses are necessary to act quickly and effectively treat them. Although conventional image classification techniques are useful, they may locate minute features in retinal images poorly, which results in the incorrect diagnosis. This work proposes a novel multi-level image classification system for eye disorders' detection and categorisation. It makes the diagnosis more accurate by use of sophisticated deep learning approaches. Shallow and deep feature extraction layers of a multi-level convolutional neural network (CNN) structure define our desired approach. This combined design allows one to present complex objects at upper levels and capture minute details at lower ones. Along with comments outlining the nature and stage of every illness, the model is taught on a vast library of retinal photographs including both healthy and diseased images. The model is made more steady using several pre-processing techniques like image normalisation, augmentation, and noise reduction. We evaluate our proposed approach against present deep learning models and standard machine learning techniques. to approach performs much better, according to data, in raising classification accuracy, precision, recall, and F1-score. When it comes to distinguish between many phases of eye illnesses, our multi-level approach outperforms conventional models. This makes it a more exact and comprehensive testing instrument. We also discuss whether the model can be used in real-life healthcare environments and in other datasets. Though it has certain issues—an uneven collecting, difficult-to-understand models, and the need for a lot of computational power—the proposed technique shows potential.

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References

Liu, X.; Zhao, C.; Wang, L.; Wang, G.; Lv, B.; Lv, C.; Xie, G.; Wang, F. Evaluation of an OCT-AI-based telemedicine platform for retinal disease screening and referral in a primary care setting. Transl. Vis. Sci. Technol. 2022, 11, 4.

Jacoba, C.M.P.; Celi, L.A.; Lorch, A.C.; Fickweiler, W.; Sobrin, L.; Gichoya, J.W.; Aiello, L.P.; Silva, P.S. Bias and non-diversity of big data in artificial intelligence: Focus on retinal diseases. Semin. Ophthalmol. 2023, 38, 433–441.

Biswas, S.S. Role of Chat GPT in Public Health. Ann. Biomed. Eng. 2023, 51, 868–869

Keenan, T.D.L.; Loewenstein, A. Artificial intelligence for home monitoring devices. Curr. Opin. Ophthalmol. 2023, 34, 441–448.

Sheng, B.; Chen, X.; Li, T.; Ma, T.; Yang, Y.; Bi, L.; Zhang, X. An overview of artificial intelligence in diabetic retinopathy and other ocular diseases. Front. Public Health 2022, 10, 971943.

Yan, Q.; Jiang, Y.; Huang, H.; Swaroop, A.; Chew, E.Y.; Weeks, D.E.; Chen, W.; Ding, Y. Genome-Wide association studies-based machine learning for prediction of age-related macular degeneration risk. Transl. Vis. Sci. Technol. 2021, 10, 29.

Yildirim, K.; Al-Nawaiseh, S.; Ehlers, S.; Schießer, L.; Storck, M.; Brix, T.; Eter, N.; Varghese, J. U-Net-Based segmentation of current imaging biomarkers in oct-scans of patients with age related macular degeneration. Stud. Health Technol. Inform. 2023, 302, 947–951.

Morelle, O.; Wintergerst, M.W.M.; Finger, R.P.; Schultz, T. Accurate drusen segmentation in optical coherence tomography via order-constrained regression of retinal layer heights. Sci. Rep. 2023, 13, 8162.

Leng, X.; Shi, R.; Wu, Y.; Zhu, S.; Cai, X.; Lu, X.; Liu, R. Deep learning for detection of age-related macular degeneration: A systematic review and meta-analysis of diagnostic test accuracy studies. PLoS ONE 2023, 18, e0284060.

Wei, W.; Southern, J.; Zhu, K.; Li, Y.; Cordeiro, M.F.; Veselkov, K. Deep learning to detect macular atrophy in wet age-related macular degeneration using optical coherence tomography. Sci. Rep. 2023, 13, 8296.

Crincoli, E.; Sacconi, R.; Querques, L.; Querques, G. Artificial intelligence in age-related macular degeneration: State of the art and recent updates. BMC Ophthalmol. 2024, 24, 121.

Chandra, R.S.; Ying, G.S. Evaluation of multiple machine learning models for predicting number of anti-VEGF injections in the comparison of AMD treatment trials (CATT). Transl. Vis. Sci. Technol. 2023, 12, 18.

Pfau, M.; Sahu, S.; Rupnow, R.A.; Romond, K.; Millet, D.; Holz, F.G.; Schmitz-Valckenberg, S.; Fleckenstein, M.; Lim, J.I.; de Sisternes, L.; et al. Probabilistic forecasting of anti-VEGF treatment frequency in neovascular age-related macular degeneration. Transl. Vis. Sci. Technol. 2021, 10, 30.

Moon, S.; Lee, Y.; Hwang, J.; Kim, C.G.; Kim, J.W.; Yoon, W.T.; Kim, J.H. Prediction of anti-vascular endothelial growth factor agent-specific treatment outcomes in neovascular age-related macular degeneration using a generative adversarial network. Sci. Rep. 2023, 13, 5639.

Fu, D.J.; Faes, L.; Wagner, S.K.; Moraes, G.; Chopra, R.; Patel, P.J.; Balaskas, K.; Keenan, T.D.L.; Bachmann, L.M.; Keane, P.A. Predicting incremental and future visual change in neovascular age-related macular degeneration using deep learning. Ophthalmol. Retina 2021, 5, 1074–1084.

You, A.; Kim, J.K.; Ryu, I.H.; Yoo, T.K. Application of generative adversarial networks (GAN) for ophthalmology image domains: A survey. Eye Vis. 2022, 9, 6.

Bai, A.; Dai, S.; Hung, J.; Kirpalani, A.; Russell, H.; Elder, J.; Shah, S.; Carty, C.; Tan, Z. Multicenter validation of deep learning algorithm ROP. AI for the automated diagnosis of plus disease in ROP. Transl. Vis. Sci. Technol. 2023, 12, 13.

Svensson, A.M.; Jotterand, F. Doctor ex machina: A critical assessment of the use of artificial intelligence in health care. J. Med. Philos. 2022, 47, 155–178.

Ethics and Governance of Artificial Intelligence for Health: WHO Guidance; World Health Organization: Geneva, Switzerland, 2021; p. 165.

McLennan, S.; Fiske, A.; Tigard, D.; Müller, R.; Haddadin, S.; Buyx, A. Embedded ethics: A proposal for integrating ethics into the development of medical AI. BMC Med. Ethics 2022, 23, 6.

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Published

2025-03-03

How to Cite

1.
Gopalbhai PV, N. Modi J. A Novel approach to multi-level image classification of Retinal Diseases. J Neonatal Surg [Internet]. 2025Mar.3 [cited 2025Sep.25];14(4S):1045-57. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/1913