GC-MS Analysis of Bio-Active Compounds in Methanolic Extract of Punica Granatum L. Root
DOI:
https://doi.org/10.52783/jns.v14.2162Keywords:
Punica granatum L. Root, Secondary metabolites, GC-MSAbstract
There have been reports of phytochemical constituents from Punica granatum L.species. There are currently no reports on phytochemical constituents or biological activity of root extracts. The objective of this study was to identify the bioactive substances in methanol extract of root of Punica granatum L. Several phytochemical constitutions were found in the root part of Punica granatum L. The methanol extract of root of Punica granatum L. was exposed to a gas chromatography-mass spectrometry (GC-MS) analysis using GC-MS equipment. The methanolic extract of Punica granatum contains a variety of phytochemical compounds, according to the GC-MS analysis. 16 compounds in all, composition of the methanolic extract, were identified. It is clear from the data that root of Punica granatum is a plant of phytopharmaceutical significance and contains a variety of phytocomponents. Additional research is required to identify the active components of the extract and to clarify their precise mechanisms of action in different disorders.
Downloads
Metrics
References
Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, Hayek T, et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. The American Journal of Clinical Nutrition. (2000); 71(5):1062-1076.
Seeram NP, Henning SM, Zhang Y, Suchard M, Li Z, Heber D. Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 h. Journal of Nutrition. (2006a); 136(10):2481-2485. 142.
Seeram NP, Schulman RN, Heber D. Pomegranates: Ancient Roots to Modern Medicine.Boca Raton: Taylor and Francis Group, (2006b), 5-8.
I. Raskin, D.M. Ribnicky, S. Komarnytsky, N. Ilic, A. Poulev, N. Borinker, D.A. Moreno, C. Ripoll, N. Yakoby. Plants and human health in the twenty-first century. Trends Biotechnol., 20 (2002), pp. 522-531
L. Reddy, B. Odhav, K.D. Bhoola. Natural products for cancer prevention: a global perspective .Pharmacol. Ther., 99 (2003), pp. 1-13
Uma B, Prabhakar K, Rajendran S, Sarayu LY. Studies on GC/MS spectroscopic analysis of some bioactive antimicrobial compounds from Cinnamomum zeylanicum. J Med Plants (2009). 8(31):125–131
Deng SX, Wang DC, Wang MD et al. The cardiac effect of Periploca sepium. Acta Pharm Sin (1964) 11:75
Hedeji I, Xu JP. Pregnane glycoside from an antitumour fraction of Periploca sepium. Phytochemistry (1988) 27:1173.
Emile JF, Abla O, Fraitag S, Horne A, Haroche J, Donadieu J, Requena-Caballero L, Jordan MB, Abdel-Wahab O, Allen CE, Charlotte F, Diamond EL, Egeler RM, Fischer A, Herrera JG, Henter JI, Janku F, Merad M, Picarsic J, Rodriguez-Galindo C, Rollins BJ, Tazi A, Vassallo R, Weiss LM; Histiocyte Society. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood. 2016 Jun 2;127(22):2672-81. doi: 10.1182/blood-2016-01-690636. Epub 2016 Mar 10. PMID: 26966089; PMCID: PMC5161007.
Brenner M. Current status of gene transfer into hamatopoietic progenitor cells: application to langerhans cell histiocytosis. Br J Cancer suppl.1994;23:S56-7
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
