A Comparative Study to Assess the Impact of Maternal Anaemia on Placenta Weight and Foetal Well-Being, in a Selected Tertiary Care Hospital, Chengalpattu District, Tamil Nadu, India
DOI:
https://doi.org/10.52783/jns.v14.2513Keywords:
N/AAbstract
Background of the study: Anaemia is the most common blood disorder that may occur during pregnancy. It has varied prevalence, etiology and degree of severity in different populations, being more common in non-industrialized countries. Anaemia is responsible for approximately 40% of maternal deaths in third world countries. It causes direct as well as indirect deaths due to cardiac failure, haemorrhage, infection and pre-eclampsia.
Methodology: Quantitative exploratory research approach was selected to assess the placental weight and fetal wellbeing among anaemic and non-anaemic pregnant women. An analytical cross-sectional design was selected for this study. Eighty two pregnant women (41 anaemic and 41 non-anaemic women), who visited the labor ward at Chrompet government hospital, Tamil Nadu, India were selected. A structured interview schedule was used to collect the demographic, placental and fetal characteristics. Comparison of the impact of maternal anaemia on placental weight and fetal wellbeing among anaemic and non-anaemic pregnant women was done.
Result and analysis: The comparative study reveals an evident statistically significant association between the placental weight and neonates birth weightamong non-anaemic pregnant women (χ2 = 17.680) at p < 0.05, which indicates that the placental weight gain has successfully influenced the birth weight of the newborn among non-anaemic pregnant women, while this association was not statistically significant among the anaemic pregnant women (χ2 = 9.938) as low haemoglobin levels have hindered the effective weight gain of the placenta and thereby birth weight of the newborn. There exist a positive correlation between the placental weight and neonate’s birth weight among anaemic and non-anaemic pregnant women which indicates that adequate weight gain of the placenta has a direct effect on the fetal weight gain and vice-versa among anaemic and non-anaemic pregnant women.
Conclusion: The study concludes that the level of haemoglobin has a positive correlation and significant association with the placental weight and birth weight of newborn which indicates that maintenance of normal haemoglobin is essential for the normal growth and development of the placenta which proportionately influences the growth of the baby. Among mothers for whom this scenario was not met it was evident that there was a vice-versa effect on the placental weight and birth weight of newborn due to low haemoglobin level. The maintenance of maternal health must ideally begin much before the childbearing age and continue further through the postpartum period in order to prevent various complications pertaining to anaemia.
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Algobashy, R.E.A., Kassem, I.K.A., Eshra, D.M.K., Effectiveness of structured teaching programme on knowledge about self-assessment of fetal well-being among primigravidae women. International journal of novel research in health care and nursing. 2020;7(3):12-21. https://www.noveltyjournals.com/upload/paper/paperpdf-1598965848.
Balcha WF, Eteffa T, Tesfu AA, Alemayehu BA, Chekole FA, Ayenew AA, Gessesse NA, Getu AA, Kassahun EA, Gezahegn TW, Adugna KF, Nega AT. Factors associated with anemia among pregnant women attended antenatal care: a health facility-based cross- sectional study. Ann Med Surg (Lond). 2023;85(5):1712-1721. doi: 10.100608.
Benoist. B., McLean, E., Egil, I., Cogswell, M., Worldwide prevalence of anaemia. 1995- 2005. WHO Global Database on Anaemia. https://apps.who.int/iris/bitstream/handle/10665/43894/9789241596657_eng.pdf;jsessionid= D975A5DFC7FE10A80F14597E2963BB6E?sequence=1.
Brar, N.K., Rawat, H.C., Text book of Advanced Nursing Practice. The Jaypee, Brothers Medical publishers. First edition. 2015;624-634.
Chinchpure, S., A comparative study to assess relationship of placental weight in normal pregnant women and in anemic pregnant women in selected hospital of Pune city. Asian J. Nur. Edu. & Research 2014;4(3): 307-313. https://i- scholar.in/index.php/Ajner/article/view/138613
Dypvik,J.,Larsen.S., Placental weight and risk of neonatal death. JAMA Pediatr. 2020 Feb; 174(2): 197–199. doi: 10.1001/jamapediatrics.2019.4556.
Eskild A, Haavaldsen C, Vatten LJ. Placental weight and placental weight to birth weight ratioinrelationtoApgar scoreatbirth:apopulationstudyof522360singletonpregnancies. ActaObstetGynecol Scand. 2014;93(12):1302-8. doi: 10.1111/aogs.12509.
Hutcheon JA, McNamara H, Platt RW, Benjamin A, Kramer MS. Placental weight for gestational age and adverse perinatal outcomes. Obstet Gynecol. 2012 Jun;119(6):1251-8. doi: 10.1097/AOG.0b013e318253d3df.
Jain,A.,Sharma,D.,Studyofplacentalweightinnormalandpre-eclampticpregnanciesand its correlation with birth weight. 2016; 4(4): DOI: https://doi.org/10.17511/ijmrr.2016.i04.15.
Janthanaphan M, Kor-Anantakul O, Geater A. Placental weight and its ratio to birth weight in normal pregnancy at Songkhlanagarind Hospital. J Med Assoc Thai. 2006;89(2):130-7. PMID: 16578997.
Jyoti R. dhagale,Acomparativestudyto assess therelationshipofplacental weight and fetal outcome among normal and anaemic mothers. Asian journal of pharmaceutical research and health care. 2017;9(4),180-185, doi: 10.18311/ajprhc/2017/16363.
Kare AP, Gujo AB. Anemia among pregnant women attending ante natal care clinic inAdare General Hospital, Southern Ethiopia: Prevalence and Associated Factors. Health Serv Insights. 2021 Jul 29;14:11786329211036303. doi: 10.1177/11786329211036303.
Kassa GM, Muche AA, Berhe AK, Fekadu GA. Prevalence and determinants of anemia among pregnant women in Ethiopia; a systematic review and meta-analysis. BMC Hematol. 2017 Oct 17;17:17. doi: 10.1186/s12878-017-0090-z.
Khatun, S., Shah, D. K., Shrestha, N., &Yadav, A. K. (2022). Ratio of Placenta to Birth Weight in Anemic and Non-AnemicMothers.Journal of Nobel Medical College,11(1), 61–
66. https://doi.org/10.3126/jonmc.v11i1.46065
Kozuki N, Lee AC, Katz J., Child health epidemiology reference group, moderate to severe, but not mild, maternal anemia is associated with increased risk of small-for-gestational-age outcomes. J Nutr. 2012 Feb;142(2):358-62. doi: 10.3945/jn.111.149237.
Kumar KJ, Asha N. Murthy DS. Sujatha MS. Manjunath VG. Maternal anemia in various trimesters and its effect on newborn weight and maturity: an observational study. International journal of preventive medicine. 2013;4(2):193. https://www.ncbi.nlm.nih.gov/pmc/issues/220970/
Lebso M, Anato A, Loha E. Prevalence of anemia and associated factors among pregnant women in Southern Ethiopia: A community based cross-sectional study. PLoS One. 2017;12(12):e0188783. doi: 10.1371/journal.pone.0188783.
Madkar, C., Musale, J., A study of placental weight and birth weight ratio (pw/bw) and it’s effects on perinatal outcome. 2015; 2(1): 1-6. ISSN: 2394-2754
Ngimbudzi EB, Massawe SN, Sunguya BF. The burden of anemia in pregnancy among women attending the antenatal clinics in Mkuranga District, Tanzania. Front Public Health. 2021 Dec 2;9:724562. doi: 10.3389/fpubh.2021.724562.
Nickel S, Gesse T, MacLaren A. Ernestine wiedenbach her Professional Legacy.Journal of nurse-midwifery 1992,37(3):161-167. DOI: 10.1016/0091-2182(92)90185-6.
Nkwabong E, Fomulu JN, Nana Njamen T. Placental fetal weight ratios among anemic and non-anemic pregnant women. Int J Pregn& Chi Birth. 2018;4(1):33-37. DOI: 10.15406/ipcb.2018.04.00079
Noronha JA, Al Khasawneh E, Seshan V, Ramasubramaniam S, Raman S. Anemia in pregnancy—consequences and challenges: a review of literature. J South Asian FederObstGynae 2012;4(1):64-70. Doi: 10.5005/jp-journals-10006-1177
Ntenda, P.A.M., Nkoka, O., Bass, P. et al. Maternal anemia is a potential risk factor for anemia in children aged 6–59 months inSouthern Africa: a multilevel analysis. BMC Public Health 18, 650 (2018). https://doi.org/10.1186/s12889-018-5568-5
Ouyang F, Parker M, Cerda S, Pearson C, Fu L, Gillman MW, Zuckerman B, Wang X. Placental weight mediates the effects of prenatal factors on fetal growth: the extent differsby preterm status. Obesity (Silver Spring). 2013;21(3):609-20. doi: 10.1002/oby.20254.
Panti AA, Ekele BA, Nwobodo EI, Yakubu A. The relationship between the weight of the placentaandbirthweightoftheneonateinaNigerianHospital.NigerMedJ.2012;53(2):80-
84. doi: 10.4103/0300-1652.103547.
Patel A, Prakash AA, Das PK, et al. Maternal anemia and underweight as determinants of pregnancy outcomes: cohort study in eastern rural Maharashtra, India. BMJ Open 2018;8:e021623. doi: 10.1136/bmjopen-2018-021623
Radan, AP.,Baud,D., Low placental weight and altered metabolic scaling after severe acute respiratory syndrome coronavirus type 2 infection during pregnancy: a prospective multicentric study. ClinMicrobiol Infect. 2022 May; 28(5): 718–722.doi: 10.1016/j.cmi.2022.02.003
Rahman MM, Abe SK, Rahman MS, Kanda M, Narita S, Bilano V, Ota E, Gilmour S, Shibuya K. Maternal anemia and risk of adverse birth and health outcomes in low- and middle-income countries: systematic review and meta-analysis. Am J ClinNutr. 2016 Feb;103(2):495-504. doi: 10.3945/ajcn.115.107896.
Rahman MM, Abe SK, Rahman MS, Kanda M, Narita S, Bilano V, Ota E, Gilmour S, Shibuya K. Maternal anemia and risk of adverse birth and health outcomes in low- and middle-income countries: systematic review and meta-analysis. Am J ClinNutr. 2016;103(2):495-504. doi: 10.3945/ajcn.115.107896.
Rahmati S, Delpishe A, Azami M, HafeziAhmadi MR, Sayehmiri K. Maternal Anemia during pregnancy and infant low birth weight: A systematic review and Meta-analysis. Int J Reprod Biomed. 2017;15(3):125-134. PMID: 28580444; PMCID: PMC5447828.
Saha S, Puwar T, Shah K, Pandya A, Wanjari MB, Saxena D. Non-iron Deficiency Anemia in Rural Indian Women: A Cross-Sectional Study. Cureus. 2022 Aug 29;14(8):e28565. doi: 10.7759/cureus.28565.
Saha, S., Pandya. AK., A studyof maternal anemia and utilizationof antenatal and postnatal care services in DevbhumiDwarka, Gujarat, Cureus. 2022 Oct; 14(10): e30427. doi: 10.7759/cureus.30427.
Salunkhe A., Salunkhe J., Kakade S., Pratinidhi, A., Association of placental weight with birth weight, Gestational age, and risk factors related to maternal morbidity, diet, activity, and rest. Journal of DattaMeghe Institute of Medical Science University. 2021;16(4):610. DOI:10.4103/jdmimsu.jdmimsu_176_20
Sarala V., A study on prevalence of anemia in pregnancy in South India. 2020;9(1) DOI: https://doi.org/10.18203/2320- 1770.ijrcog20195617
Sharma, S., Kaur. SP., Anemia in pregnancy is still a public health problem: a single centerstudywith review of literature. Indian J Hematol Blood Transfus. 2020 Jan; 36(1): 129–134. doi: 10.1007/s12288-019-01187-6
Sinha, A., Adhikary, M., A study on anemia and its risk factors among pregnant women attending antenatal clinic of a rural medical college of West Bengal. J Family Med Prim Care. 2021 Mar; 10(3): 1327–1331. doi: 10.4103/jfmpc.jfmpc_1588_20
Suryanarayana R, Chandrappa M, Santhuram AN, Prathima S, Sheela SR. Prospective study on prevalence of anemia of pregnant women and its outcome: A community based study. J Family Med Prim Care. 2017;6(4):739-743. doi: 10.4103/jfmpc.jfmpc_33_17.
Turowski G, Tony Parks W, Arbuckle S, Jacobsen AF, Heazell A. The structure and utility of the placental pathology report. APMIS 2018; 126(7): 638-646. https://doi.org/10.1111/apm.12842.
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