Histopathological Pattern In Turp Specimens Analysed Retrospectively In A Tertiary Care Hospital
DOI:
https://doi.org/10.52783/jns.v14.2534Keywords:
Prostate, Benign Prostatic Hyperplasia (BPH), Prostate Cancer, Prostate Adenocarcinoma, Chronic Prostatitis (CP), Transurethral Resection of the Prostate (TURP), Histopathology, Incidental Prostate Cancer, Gleason Score, Retrospective StudyAbstract
Background: The prostate is a retroperitoneal organ without a clear capsule that surrounds the neck of the bladder and urethra. The prostate gland is impacted by only three pathologic processes frequently enough to warrant discussion: tumours, benign prostatic hypertrophy (BPH), and inflammation. BPH is the most prevalent of them and affects older men so frequently that it is practically considered a "normal" aspect of ageing. Prostate transurethral resection(TURP) is a routine procedure. Typically, these specimens show benign prostatic hyperplasia. On the other hand, incidental prostate cancer is occasionally seen.
Objective: To examine different histological patterns in TURP specimens that were collected by the Department of Pathology between January 2020 and December 2023.
Materials and methods: This study is a retrospective observational analysis of TURP specimens that were received between January 2020 and December 2023 by the Department of Pathology at the SSPM Lifetime Medical College and Hospital. Standard techniques were used to identify and categorise a variety of lesions. Standard techniques were employed to classify prostate cancers that were incidentally discovered. The WHO classified and rated incidentally discovered prostate cancers using a modified Gleason's score.
Results: Out of 84 TURP specimens, 19 (25%) were transitional epithelium, 33 (43%) were Benign Prostatic Hyperplasia (BPH), 21 (28%) were chronic prostatitis (CP), Benign prostatic hyperplasia with chronic prostatitis (Fig 3), and 6 (8%) were prostate adenocarcinoma.
Conclusion: Histopathological examination of prostatic lesions aids in incidental detection of prostatic adenocarcinoma who missed clinical suspicion and were operated for other reason. Early diagnosis and treatment can reduce mortality and morbidity associated with prostatic lesions.
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