Efficient Multi-Class Classification of NSCLC Subtypes with Transfer Learning-Enhanced CNNs on Augmented CT Data

Authors

  • Jayabharathi S
  • V Ilango
  • Nikitha Pai
  • Shamitha S K

DOI:

https://doi.org/10.52783/jns.v14.2764

Keywords:

Lung cancer detection, Medical Imaging, Deep learning, Transfer learning, Data augmentation

Abstract

The second most cancer related deaths are caused by lung cancer, since this cancer type has highest mortality rate. The early diagnosis of Lung cancer is crucial as there are possibilities to increases the survival rate. Conventional diagnostic methods often rely on human interpretation of medical images which is time consuming and are prone to error. In this research we proposed a Novel hybrid model LungNetB5 for multi-class lung cancer classification and prediction. CNN and Efficient Net are integrated into single architecture which blends traditional CNN feature extraction layers with the powerful feature learning capabilities of EfficientNet. The experiments are carried on “MCLCI” dataset for NSCLC lung cancer patients. To overcome the biases, class imbalance problem was addressed using data augmentation techniques. The developed LungNetB5 model attained 92% accuracy. The predicted results show that EfficientNet class based LungNetB5 outperforms other CNN models in terms of efficiency and accuracy. In addition, it is faster and need very less parameters to train when compared to other CNN models, making it a viable experiment for extensive clinical settings and a promising tool for automated detection of lung cancer from CT images.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Ganfeng Luo, Yanting zhang, Jaione E,Meland A,Xiuyu C, Yunatao H, Huachun Z(2023), “projections of lung cancer incidence by 2035 in 40 countries worldwide: population based study”.

Jing Ning, Tao Ge, Minlin Jiang, Keyi Jia, Lei wang,Wei Li, Bin chen, Yu liu, Hao wang, sha Zao, Yayi He(2021), “ Early diagnosis of Lung cancer : which is the optimal choice”, PubMed, PMID:33591942

A Asuntha, Andy Srinivasan (2020).” Deep learning for lung cancer detection and classification”, springer, multimedia tools and applications.79:7731-7762

Michael K G, Jessica D, William R L, Peter J M, David E M, David P M, Renda S W (2013), “Evaluation of individuals with pulmonary nodules: When it is Lung Cancer?”, PubMed, PMID:23649456

Ioannis V, Konstantinos S, Sarah S, Arjun N, Charles S, Joanne M (2018),” Lung cancer screening: Nodule identification and characterization”, PMID :30050767.

Donald P F, Michael J C,Brian D C, Helen R N, R Paul Gillerman (2024),” Comparing of different imaging modalities used to image pediatric oncology patient: A COG diagnostic imaging committee,/SPR oncology committee white paper”, Pubmed central PMID:-3702533

Ahmed H, Chintan P, John Q, Lawrence H S, Hugo J W L A (2018),,“ Artificial Intelligence in radiology”, PMID : 29777175

Dr. R sarvamangala, Raghavendra v k (2022), “Convolutional neural networks in medical image understanding a survey”, Evolutionary intelligence 2022,

Xiaoyan J,Zuiojin hu,Shuihua W, Yudong Z(2023),”Deep learning for medical image-based cancer diagnosis, PMID:37509272

Y kaya, Ercan G (2023), “A MobileNet based CNN model with a fine tuning mechanism for COVID-19 infection detection”, Soft Computing, Data analytics and Machine learning, springer,voulume -27,pages 5521-5535.

Lyu Lei (2021), “Lung cancer based on convolutional neural networks ensemble model”, 2nd international seminar on Artificial intelligence, Networking and Information technology, AINIT, IEEE (2021).

R Raza, Fathima Z, Md. Owais Khan, Md Arif, Atif A, Md Aksam Ifthikar, Tanvir A(2023),”Lung-EffNet : lung cancer classification using EfficientNet from CT scan images, Engineering Apllications of Artificial Intelligence, Vol 126. Part B, 106902

V Sreepada, Dr K Vedavathi(2023), “Lung cancer detection from X-ray images using hybrid deep learning technique”, 3rd Intl.conference on Evolutionary computing and more sustainable networks.

Suren M, P W C Prasad, Abeer A, A K singh, A Elchouemi(2018), “ Lung cancer detection using CT images”, procedia computerscience, volume 125, 2018, pages 107-114

Sunila A, Imran A, Md Asif, Hanan A, Fahad A, Yazeed Y G, Rashad E (2023), “Lung cancer classification in histopathological images using multiresolution EfficientNets”, Computational Intelligence and Neuro science.

Juan J, Monzo E, Lozano C et.al (2023), “Computer assisted diagnoasis for an early identification of lung cancer in chest x-rays”, sci rep 13, 7720(2023), https://doi.org/10.1038/s41598-023-34835-z

Faridoddin S, Mojtaba M (2019),” Applications of CAD systems for automatic detection of lung nodules”, informatics in medicine unlocked, volume 15, 2019,100173.

Bharathy S, Pavithra R, Akshaya B(2022), “Lung cancer detection using machine learning”,2022 Intl conference on applied artificial intelligence and computing.

Mayued S Al H, Furat Y M,Enam A K,Zainab H , Hamadalla F, Hamadalla F Al-Haisary (2021),” Evaluation of SVM performance in the detection of lung cancer in marked CT scan dataset”, Indonesian journal of Electrical engineering and computer science. march 2021

R Pandian, V Vedanarayanan, D N S Ravikumar, R Rajakumar(2022), “Detection and classification of lung cancer using CNN and Google net, Measurement: sensors, volume 24, December 2022, 100588

Asghar A S, Hafiz abid M M, Abdulla H M, Abdulla A, Zaeem A B(2023), “Deep learning Ensemble 2D approach towards the detection of lung cancer”, Scientific reports. 13, article number 2987

Mamoona H, R sujatha, Saleh N A, N Z Jhanji (2022), “The transfer learning approach with a convolutional neural network for classification of lung carcinoma”, healthcare 2022, 10,1058

Muniasamy A, Alquthani, salma A S,Bilfaqih , Syeda M, Balaji, prasanalakshmi, Karunakaran, Gauthamanan(2023), “lung cancer histopathological image classification using transfer learning with convolutional neural network”, Technology and healthcare, vol 32, no.2, pp-1199-1210.

Abdulrazak Y S, Chee ka chin, Vanessa P, Hamada R H Al-absi(2021), “Lung cancer medical image classification using hybrid CNN and SVM”, Intl journal of adance in intelligent informatics, vol 7, no 2, July 2021, pp-151-162

Anindita S, Shahid M G, Pijush K D P, Rakes K Y, Saurav M, Zhongming Z (2024), “VER-Net: a hybrid transfer learning model for lung cancer detection using CT scan images”, BMC medical imaging, 24, article no 120.

Md.Q. Shatnavi, Qusai A, Romessa Al-Quraan(2025), “Deep learning based approach to diagnose lung cancer using CT images”, Intelligence-based medicine, volume 11, 2025,100188

Downloads

Published

2025-03-29

How to Cite

1.
S J, Ilango V, Pai N, S K S. Efficient Multi-Class Classification of NSCLC Subtypes with Transfer Learning-Enhanced CNNs on Augmented CT Data. J Neonatal Surg [Internet]. 2025Mar.29 [cited 2025Sep.17];14(10S):48-60. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/2764