Extraction, Spectral Analysis and Pharmacological Action of Jackfruit Seeds Extract

Authors

  • Vaibhav P. Uplanchiwar
  • Trinayan Deka
  • Ranjeet Yadav
  • Sanjay Mishra
  • B. Sanjeeb Kumar Patro
  • Tahira Sultan
  • Sohan Lal
  • Shilpa Rani

DOI:

https://doi.org/10.52783/jns.v14.2872

Keywords:

Pathogenic bacteria, A. heterophyllus Lam., Root bark, Antioxidant

Abstract

Medicines made from plants have greatly benefited humanity by helping to treat bacterial diseases. In order to ensure safety and efficacy in the face of synthetic antibiotics' multidrug resistance, plants are now utilised in the pharmaceutical industry to manufacture innovative drugs. The current work sought to determine the antibacterial and phytochemical screening capability of A. heterophyllus ethanolic extracts. The produced ethanolic extract (EE) underwent phytochemical analysis, which revealed the presence of terpenoids, amino acids, alkaloids, glycosides, phenolic, and flavonoids. The DPPH and ABTS techniques were used to determine the antioxidant content and antioxidant studies of the ethanolic extract (EAE) of the root bark of A. heterophyllus Lam. By calculating the minimum inhibitory concentration (MIC) and zone of inhibition, the extract with the highest antioxidant property (EAE) was chosen for antibacterial investigations against bacterial strains. The findings of the research on antibacterial and antioxidant properties were encouraging.

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References

Rawani A, Pal S, Chandra G. Evaluation of antibacterial properties of four plant extracts against human pathogens. Asian Pac J Trop Biomed. 2000;1:s71–5.

Chatterjee SK, Bhattacharjee I, Chandra G. Bactericidal activities of some common herbs in India. Pharm Biol. 2007;45:350–4.

Abraham J, Chakraborty P, Chacko AM, Khare K. Cytotoxicity and antimicrobial effects of Pistia stratiotes leaves. Int J Drug Dev & Res. 2014;6(4):208–21.

Bhattacharya K, Burman S, Nandi S, Roy P, Chatterjee D, Chandra G. Phytochemical extractions from the leaves of Ravenala madagasariensis from Sundarban area and its effect on southern house mosquito ( Culex quinquefasciatus Say 1823) larvae. J Mosq Res. 2014;4(12):1–6.

Singh A, Bhattacharya K, Chandra G. Efficacy of Nicotiana plumbaginifolia (Solanaceae) leaf extracts as larvicide against malarial vector Anopheles stephensi Liston 1901. Int J pharma bio Sci. 2015; 6(1): (b) 860–868.

Mukherjee D, Bhattacharya K, Chandra G. Extracts of edible pods of Moringa oleifera lam. (Moringaceae) as novel antibacterial agent against some pathogenic bacteria. Int J Pharma Bio Sci 2015; 6(3): (B) 513–520.

Dellavalle PD, Cabrera A, Alem D, Larrañaga P, Ferreira F, Rizza MD. Antifungal activity of medicinal plant extracts against phytopathogenic fungus Alternaria spp. Chil J Agri Res. 2011;71(2):231–9.

Baroni S, Suzuki-Kemmelmeier F, Caparroz-Assef SM, Cuman RKN, Bersani-Amado CA. Effect of crude extracts of leaves of Smallanthus sonchifolius (Yacon) on glycemia in diabetic rats. Braz J Pharm Sci. 2008;44(3):511–30.

Vishvakrama P, Sharma S. Liposomes: an overview. Journal of Drug Delivery and Therapeutics. 2014 Jun 24:47-55.

Vishvakarma P. Design and development of montelukast sodium fast dissolving films for better therapeutic efficacy. Journal of the Chilean Chemical Society. 2018 Jun;63(2):3988-93.

Vishvakarma P, Mandal S, Verma A. A review on current aspects of nutraceuticals and dietary supplements. International Journal of Pharma Professional’s Research (IJPPR). 2023;14(1):78-91.

Prabhakar V, Agarwal S, Chauhan R, Sharma S. Fast dissolving tablets: an overview. International Journal of Pharmaceutical Sciences: Review and Research. 2012;16(1):17.

Arung ET, Wicaksono BD, Handoko YA, Kusuma IW, Yulia D and Sandra F: Anti-cancer properties of diethylether extract of wood from Sukun (Artocarpus altilis) in human breast cancer (T47D) cells. Trop J Pharm Res 2009; 8(4): 317-24.

Yusuf S, Srinivasan KK and Harindran J: Indigenous claim supports in-vitro antioxidant and cytotoxic screening of certain South Indian Medicinal Plants. J Pharm Biol Sci 2017; 12(3): 53-6.

Combretum roxburghii Spreng. The Plant List: A working list of all plant species. http://www.theplantlist.org/tpl1.1/record/kew-2732996. Accessed 19 July 2017.

Vishvakarma P, Mandal S, Pandey J, Bhatt AK, Banerjee VB, Gupta JK. An Analysis Of The Most Recent Trends In Flavoring Herbal Medicines In Today's Market. Journal of Pharmaceutical Negative Results. 2022 Dec 31:9189-98

Begum T, Amit Sarker A, Akhter S. Comparative study on Combretum and Terminalia species of the Combretaceae family. Pharmacophore. 2016;7(1):41–3.

Prabhakar V, Agarwal S, Chauhan R, Sharma S. Fast dissolving tablets: an overview. International Journal of Pharmaceutical Sciences: Review and Research. 2012;16(1):17

Ncube NS, Afolayan AJ, Okoh AI. Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends. Afr J Biotechnol. 2008;7(12):1797–806.

Chopra NR, Nayar S L, Chopra IC. Glossary of Indian medicinal plants (including the supplement). CSIR, New Delhi.1986.

Chackrewarthy S and Thabrew MI: Hypoglycaemic and hypolipidaemic effects of an ethylacetate fraction of Artocarpus heterophyllus leaves. In: Glucose Tolerance. 2012; 207-22.

Vazhacharickal PJ, Mathew JJ, Kuriakose AC, Abraham B, Mathew RJ and Albin AN: Chemistry and medicinal properties of jackfruit (Artocarpus heterophyllus): a review on current status of knowledge. Int J Innov Res Rev 2015; 3(2): 83-95.

Patel RM and Patel SK: Cytotoxic activity of methanolic extract of artocarpus heterophyllus against a549, hela and mcf-7 cell lines. J Appl Pharm Sci 2011; 1(7): 167-71.

Ranasinghe RASN, Maduwanthi SDT and Marapana RAUJ: Nutritional and Health Benefits of Jackfruit (Artocarpus heterophyllus Lam.): A Review. Int J Food Sci. 2019; 1-12.

Yusuf S, Reshma S, Melvin P, Jaleel FA, Pr S and Harindran J: Estimation of secondary metabolites from the root bark extracts of Artocarpus heterophyllus Lams. Res J Pharm Biol Chem Sci 2018; 9(4): 766-72.

Bhatnagar S, Sunita Sahoo S, Mohapatra AK, and Behera DR. Phytochemical analysis, antioxidant and cytotoxic activity of medicinal plant Combretum roxburghii (family: Combretaceae). January-march. 2012 2014; 4(1):193–202.

Singha Ray A, Bhattacharya K, Chandra G. Target specific larvicidal effect of Capparis zeylanica (Capparaceae) foliages against filarial vector Culex quinquefasciatus Say (1823). Int J pharm bio Sci. 2015; 6(3): (B) 139–148.

Bhattacharya K, Chandra G. Phagodeterrence, larvicidal and oviposition deterrence activity of Tragia involucrata L. (Euphorbiaceae) root extractives against vector of lymphatic filariasis Culex quinquefasciatus (Diptera: Culicidae). Asian Pac J Trop Dis. 2014;4(1):226–32.

Bhattacharjee I, Chatterjee SK, Ghosh A, Chandra G. Antibacterial activities of some plant extracts used in Indian traditional folk medicine. Asian Pac J Trop Biomed. 2011:s165–9.

National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disc susceptibility tests. Approved standard NCCLS Publications M2-A5. Villanova, PA, USA .1993.

Swami SB, Thakor NJ, Haldankar PM and Kalse SB: Jackfruit and Its Many Functional Components as Related to Human Health: A Review. Compr Rev Food Sci Food Saf 2012; 11(6): 565-76.

Tyagi S. Medicinal uses of Jackfruit (Artocarpus heterophyllus). In: XII Agricultural Science Congress, ICAR, National diary Research Institute, Karnal, Haryana, India. 2015.

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Published

2025-04-01

How to Cite

1.
P. Uplanchiwar V, Deka T, Yadav R, Mishra S, Kumar Patro BS, Sultan T, Lal S, Rani S. Extraction, Spectral Analysis and Pharmacological Action of Jackfruit Seeds Extract. J Neonatal Surg [Internet]. 2025Apr.1 [cited 2025Sep.19];14(6):118-24. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/2872

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