An Accurate Ckd Prediction Model With Using Integrated Layered Network With Optimizer
DOI:
https://doi.org/10.52783/jns.v14.3009Keywords:
CKD, deep learning, layered network, optimization, predictionAbstract
Predictive modeling course of CKD and ensuring early diagnosis is essential for individualized treatment that may enhance patients' quality of life and prolong survival time. Using readily available clinical and laboratory data from patients with mental health conditions CKD, this thesis investigates the interpretability of statistical learning and computer vision models for predicting end-stage renal disease. Machine-learning models were used with clinical, comorbid, and demographic data to ascertain whether a patient with CKD would experience end-stage renal disease. The most significant markers were discovered using the proposed Lightweight Layered Network (LLNet) with Stochastic Gradient Descent (SGD). Researchers also added sophisticated attribution techniques to improve the intelligibility of the neural network architecture. The neural network architecture had a much higher AUC-ROC of 99% than the baseline models. While the existing interpretation was inconsistent, the interpretation produced by Lightweight Layered Network (LLNet) with Stochastic Gradient Descent (SGD) with attribution techniques aligned with clinical expertise. There were negative connections between eGFR and urine creatinine with the progression of CKD, although positive relationships were seen with urine albumin to creatinine ratio, potassium, hematuria, and proteinuria. In conclusion, attribution algorithms combined with deep learning can detect comprehensible aspects of the development of CKD. Our model found several essential but underreported characteristics that could be new indicators of the advancement of CKD. This study gives doctors a strong, empirically supported basis for using predictive analytics in the healthcare management and therapy of CKD.
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Fadem, Introduction to Kidney Disease, Staying Healthy With Kidney Disease: A Complete Guide for Patients. Cham, Switzerland: Springer, 2022.
Zisser and D. Aran, ‘‘Transformer-based time-to-event prediction for CKD deterioration,’’ J. Amer. Med. Inform. Assoc., vol. 31, no. 4, pp. 980–990, Apr. 2024.
Ammirati, ‘‘CKD,’’ Revista da Associadica Brasileira, vol. 66, no. 1, pp. s03–s09, Jan. 2020.
Aljaaf, D. Al-Jumeily, H. M. Haglan, M. Alloghani, T. Baker, A. J. Hussain, and J. Mustafina, ‘‘Early prediction of CKD using machinelearningsupportedbypredictiveanalytics,’’ in Proc. IEEE Congr. Evol. Comput. (CEC), Jul. 2018, pp. 1–9.
Ekanayake and D. Herath, ‘‘CKD prediction using predictive analytics methods,’’ in Proc. Moratuwa Eng. Res. Conf. (MERCon), Jul. 28, 2020, pp. 260–265.
Ifraz, M. H. Rashid, T. Tazin, S. Bourouis, and M. M. Khan, ‘‘Comparative analysis for prediction of kidney disease using intelligent predictive analytics methods,’’ Comput. Math. Methods Med., vol. 2021, pp. 1–10, Dec. 2021.
Ahmed, M. A. Ali, N. Ahmed, and T. Bhuiyan, ‘‘Computational intelligence approaches for prediction of CKD,’’ in Advances in Distributed Computing and Predictive analytics. Cham, Switzerland: Springer, 2021.
A. N, and K. S. K, ‘‘Decision tree-based explainable AI for diagnosis of CKD,’’ in Proc. 5th Int. Conf. Inventive Res. Comput. Appl. (ICIRCA), Aug. 2023, pp. 947–952.
Tran, M. Zhang, P. Andreae, B. Xue, and L. T. Bui, ‘‘Multiple imputation and ensemble learning for classification with incomplete data,’’ in Proc. 20th Asia Pacific Symp., Nov. 2016, pp. 401–415.
Sarkar, and M. Ahmed, ‘‘Comprehensive performance assessment of neural network architectures in early prediction and risk identification of CKD,’’ IEEE Access, vol. 9, pp. 165184–165206, 2021.
Karita, N. Chen, T. Hayashi, T. Hori, H. Inaguma, Z. Jiang, M. Someki, N. E. Y. Soplin, R. Yamamoto, X. Wang, S. Watanabe, T. Yoshimura, and W. Zhang, ‘‘A comparative study on transformer vs RNN in speech applications,’’ in Proc. IEEE Autom. Speech Recognit. Understand. Workshop (ASRU), Dec. 2019, pp. 449–456.
Song and Y. Lu, ‘‘Decision tree methods: Applications for classification and prediction,’’ Shanghai Arch. Psychiatry, vol. 27, no. 2, p. 130, Apr. 2015.
Amlashi, P. Alidoust, M. Pazhouhi, K. P. Niavol, S. Khabiri, and A. R. Ghanizadeh, ‘‘AI-based formulation for mechanical and workability properties of eco-friendly concrete made by waste foundry sand,’’ J. Mater. Civil Eng., vol. 33, no. 4, Apr. 2021, Art. no. 04021038.
Rubini, P. Soundarapandian, and P. Eswaran, ‘‘CKD,’’ UCI Mach. Learn. Repository, 2015. [Online]. Available: https://doi.org/10.24432/C5G020
Elreedy and A. F. Atiya, ‘‘A comprehensive analysis of synthetic minority oversamplingtechnique(SMOTE)forhandlingclassimbalance,’’ Inf. Sci., vol. 505, pp. 32–64, Dec. 2019.
Beretta andA.Santaniello, ‘‘Nearest neighbor imputation algorithms: A critical evaluation,’’ BMC Med. Informat. Decis. Making, vol. 16, no. S3, pp. 197–208, Jul. 2016.
Aljaaf, D. Al-Jumeily, A. J. Hussain, T. Dawson, P. Fergus, and M.Al-Jumaily, ‘‘Predicting the likelihood of heart failure with a multi level risk assessment using decision tree,’’ in Proc. 3rd Int. Conf. Technol. Adv. Electr., Electron. Comput. Eng. (TAEECE), Apr. 2015, pp. 101–106.
Saqlain, M. Sher, F. A. Shah, I. Khan, M. U. Ashraf, M. Awais, and A. Ghani, ‘‘Fisher score and Matthews correlation coefficient-based feature subset selection for heart disease diagnosis using support vector machines,’’ Knowl. Inf. Syst., vol. 58, no. 1, pp. 139–167, Jan. 2019
Javeed, S. Zhou, L. Yongjian, I. Qasim, A. Noor, and R. Nour, ‘‘An intelligent learning system based on random search algorithm and optimized random forest model for improved heart disease detection,’’ IEEE Access, vol. 7, pp. 180235–180243, 2019.
Ambrish, B. Ganesh, A. Ganesh, C. Srinivas, and K. Mensinkal, ‘‘Logistic regression technique for prediction of cardiovascular disease,’’ Global Transitions Proc., vol. 3, no. 1, pp. 127–130, Jun. 2022.
Abdellatif, H. Abdellatef, J. Kanesan, C.-O. Chow, J. H. Chuah, and H. M.Gheni,‘‘Improving the heart disease detection and patients’ survival using supervised infinite feature selection and improved weighted random forest,’’ IEEE Access, vol. 10, pp. 67363–67372, 2022.
Khan and F. Algarni, ‘‘A healthcare monitoring system for the diagnosis of heart disease in the IoMT cloud environment using MSSO ANFIS,’’ IEEE Access, vol. 8, pp. 122259–122269, 2020.
Barfungpa, H. K. Deva Sarma, and L. Samantaray, ‘‘An intelligent heart disease prediction system using hybrid deep dense Aquila network,’’ Biomed. Signal Process. Control, vol. 84, Jul. 2023, Art. no. 104742.
Akella and S. Akella, ‘‘Predictive analytics algorithms for predicting coronary artery disease: Efforts toward an open source solution,’’ Future Sci. OA, vol. 7, no. 6, Jul. 2021, Art. no. FSO698
Srinivas and R. Katarya, ‘‘HyOPTXg: OPTUNA hyper-parameter optimization framework for predicting cardiovascular disease using XGBoost,’’ Biomed. Signal Process. Control, vol. 73, Mar. 2022, Art. no. 103456.
Mohan, C. Thirumalai, and G. Srivastava, ‘‘Effective heart disease prediction using hybridmachinelearningtechniques,’’IEEEAccess,vol.7, pp. 81542–81554, 2019.
Ali, A. Niamat, J. A. Khan, N. A. Golilarz, X. Xingzhong, A. Noor, R. Nour, and S. A. C. Bukhari, ‘‘An optimized stacked support vector machines based expert system for the effective prediction of heart failure,’’ IEEE Access, vol. 7, pp. 54007–54014, 2019.
Almazroi, E. A. Aldhahri, S. Bashir, and S. Ashfaq, ‘‘A clinical decision support system for heart disease prediction using deep learning,’’ IEEE Access, vol. 11, pp. 61646–61659, 2023.
Subramani, N. Varshney, M. V. Anand, M. E. M. Soudagar, L. A. Al-keridis, T. K. Upadhyay, N. Alshammari, M. Saeed, K. Subramanian, K. Anbarasu, and K. Rohini, ‘‘Cardiovascular diseases prediction by predictive analytics incorporation with deep learning,’’ Frontiers Med., vol. 10, Apr. 2023
Polat, H. Danaei Mehr, and A. Cetin, ‘‘Diagnosis of CKD based on support vector machine by feature selection methods,’’ J. Med. Syst., vol. 41, no. 4, p. 55, Apr. 2017.
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