Phytochemical Profiling And Antioxidant Potential Of Boerhaavia Diffusa
DOI:
https://doi.org/10.52783/jns.v14.3108Keywords:
Boerhaavia diffusa, GC-MS analysis, antioxidant activity, radical scavenging, phytochemicals, medicinal plantsAbstract
The present study investigates the phytochemical composition and antioxidant potential of Boerhaavia diffusa, a plant known for its traditional medicinal uses. Gas Chromatography-Mass Spectrometry (GC-MS) analysis was employed to identify and characterize 15 bioactive compounds present in the plant’s extract, revealing a diverse array of pharmaceutical and therapeutic properties. Key compounds identified include β-D-Glucopyranose (antioxidant, anti-inflammatory), 2, 2'-Dipiperidine (CNS stimulant, neuroprotective), Aziridine (anticancer), 4-Octadecenal (wound healing, antimicrobial), and cis-13-Octadecenoic acid (cardioprotective, anti-inflammatory). These bioactive compounds suggest that Boerhaavia diffusa holds significant potential for applications in diabetes management, neuroprotection, cardiovascular health, antimicrobial formulations, and cancer therapy. Additionally, the antioxidant activity of the plant was assessed through two different radical scavenging assays: DPPH and ABTS. The DPPH assay revealed an IC₅₀ value of 384.08 µg/mL, indicating moderate antioxidant activity, while ascorbic acid, the standard antioxidant, exhibited a slightly lower IC₅₀ value of 415.98 µg/mL, suggesting stronger radical scavenging potential. Similarly, the ABTS assay recorded an IC₅₀ value of 454.79 µg/mL for Boerhaavia diffusa, with ascorbic acid again demonstrating a superior antioxidant effect (IC₅₀ = 348.24 µg/mL). These results collectively highlight the moderate antioxidant potential of Boerhaavia diffusa, supporting its traditional use in various therapeutic applications. Further research is warranted to explore the precise mechanisms underlying its bioactive properties and to evaluate its potential in clinical settings.
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