A Study Of Lipid Profile In Hypertensive Patients

Authors

  • Siddharth Shah
  • Yash Shah
  • Puneet Upadhyay
  • Shubham Darda

DOI:

https://doi.org/10.52783/jns.v14.3369

Keywords:

Hypertension, Lipid Profile, Stroke, Ischemic Heart Disease (IHD)

Abstract

In terms of public health, hypertension ranks among the top causes of death and disability worldwide. Untreated hypertensive has a higher prevalence of dyslipidaemia than normotensives do, and lipid levels rise as blood pressure does. This study was directed towards the study of various lipid profile variables in hypertensive patients as well as it compared the lipid levels in IHD and stroke patients.

Aims & Objectives: To study the lipid profile in patients of hypertension, to evaluate the abnormality of lipid profile (TC, TG, HDL-c, LDL-c, VLDL-C, TC/HDLc, LDL-c/HDL-c) in hypertensive patients and to compare the lipid levels in stroke and Ischemic Heart Disease hypertensive patients.

Methodology: This study employed a cross-sectional design. Patients from the OPD as well as those admitted to the ward and intensive care unit of the General Medicine Department at Dhirai Hospital, Sumandeep Vidyapeeth, participated in this study. Out of the 100 individuals who were enrolled in the study, 50 patients with hypertension (both previously diagnosed and newly discovered cases) were chosen to participate in the research. The control population consisted of 50 patients without hypertension or its complications.

Results: In our study, the minimum age of the patient was 24 years and maximum age is 86 years, the mean age was 53.67 years. Most hypertension patients in the study were between the ages of 51-60 years. In our study, 39 patients had hyperlipidaemia; all the parameters in lipid profile were raised in hypertensive population when compared it with healthy controls (normotensives);TC and LDL (P=0.0444) was raised in hypertensive patients having Stroke;  the TC/HDL-c levels were raised in males as compared to females; all the parameters in lipid profile were raised in hypertensive population with IHD then with non-IHD patients; among hypertensive patients who consume alcohol, it was observed that TC, TGL and VLDL-c were raised while HDL-c were reduced in the same group.

Conclusion: Our study indicates that the lipid profile of hypertension patients differs significantly from that of non-hypertensive individuals.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Kannel WB, Castelli WP, Gordon T, McNamara PM. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. Ann Intern Med. Published online 1971. doi:10.7326/0003-4819-74-1-1

Williams RR. Hunt SC, Hopkins PN, et al. Familial Dyslipidemic Hypertension: Evidence From 58 Utah Families for a Syndrome Present in Approximately 12% of Patients With Essential Hypertension. JAMA J Am Med Assoc. Published online 1988. doi:10.1001/jama. 1988.03720240041032

Saha M. Sana N, Shaha RK. Serum Lipid Profile of Hypertensive Patients in the Northern Region of Bangladesh. J Bio-Science. Published online 2006. doi:10.3329/jbs.v1410.450

Kumar V. The Relationship between Lipid Profile and Hypertension. J Med Sci Clin Res. Published online 2017. doi:10.18535/jmser/v5i12.159

Diana Shintawati Purwanto, Yanti Meilen Mewo, Edmond Leonard Jim. Evaluation of Lipid Profile on Hypertensive Patients: An Observational Study from North Sulawesi, Indonesia, Cardiology and Cardiovascular Research. Volume 6, Issue 1, March 2022, pp. 39-44. doi: 10.11648/j.ccr.20220601.16.

Wu, Yuan Lu, Xiaochen Wang, Xinyue Li, George C Linderman, Chaoqun Wu, Xiuyuan Cheng, Lin Mu, Haibo Zhang, Jiamin Liu, Meng Su, Hongyu Zhao, Erica S Spatz, John A Spertus, Frederick A Masoudi, Harlan M Krumholz, Lixin Jiang. Prevalence, awareness, treatment, and control of hypertension in China: data from 1-7 million adults in a population-based screening study (China PEACE Million Persons Project), The Lancet, Volume 390, Issue 10112,2013,Pages 2549-2558,ISSN 0140-6736,https://doi.org/10.1016/S0140- 6736(17)32478-9.

A. S. Hakim, S. A. Kamath and Mamata, "A Retrospective Study of Lipid Profile in 500 Hypertensive Patients," Journal of the Association of Physicians of India, Vol. 45, No. 12, 1997, pp. 943-944.

Kara H, Bonna, Dag S. Association between blood pressure and serum lipids in a population-The Tromso study. Circulation, 1991; 83(4): 1305-13

A. Alloubani, et al., Hypertension and diabetes mellitus as a predictive risk factors for stroke, Diab Met Syndr: Clin Res Rev (2018). https://doi.org/10.1016/j.dsx.2018.03.009

Mishra A, Lal A. Sahu KK, George AA, Martin K, Sargent J. An Update on Pulmonary Hypertension in Coronavirus Disease-19 (COVID-19). Acta Biomed. 2020;91(4):e2020155. Published 2020 Nov 10. doi:10.23750/abm.v9114.10698 Res.2022.

Ulla SS, D'Souza V, Bhat BM. Evaluation of Lipid Profile and Antioxidant Status in Hypertensive Smokers: A Case-control Study J Clin of Diagn https://www.doi.org/10.7860/JCDR/2022/55196/16223 16(4):BC08-BC12.

Park H, Kim K. Association of alcohol consumption with lipid profile in hypertensive men. Alcohol Alcohol. 2012 May-Jun;47(3):282-7. doi: 10.1093/alcalc/ags019. Epub 2012 Feb 26. PMID: 22371847.

Downloads

Published

2025-04-10

How to Cite

1.
Shah S, Shah Y, Upadhyay P, Darda S. A Study Of Lipid Profile In Hypertensive Patients . J Neonatal Surg [Internet]. 2025Apr.10 [cited 2025Oct.2];14(13S):835-41. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/3369

Most read articles by the same author(s)