Phytochemical Characterization and Therapeutic Potential of Catechin in the Treatment of Urinary Tract Infections
DOI:
https://doi.org/10.63682/jns.v14i14S.4047Keywords:
Prevalence, therapeutic, phytochemicals, antimicrobial, pathogenAbstract
Background: Urinary Tract Infections (UTIs) are a prevalent global health concern, often caused by bacterial pathogens such as Escherichia coli. Investigating natural substances for their potential as a treatment for UTIs has gained popularity in recent years.
Methods: This research focuses on the phytochemical characterization of Tea leaf extracts and the specific emphasis on catechin, a flavonoid known for its potent antioxidant and antimicrobial properties.
Result/Conclusions: The paper provides an in-depth analysis of the existing literature on the subject, highlighting the potential of catechin as a novel and effective treatment for UTIs.
Downloads
Metrics
References
Yuan S, Chan HCS, Hu Z. Using PyMOL as a platform for computational drug design. Wiley Interdiscip Rev Comput Mol Sci. 2017;7(2). doi:10.1002/wcms.1298
Ma Y, Ding S, Fei Y, Liu G, Jang H, Fang J. Antimicrobial activity of anthocyanins and catechins against foodborne pathogens Escherichia coli and Salmonella. Food Control. 2019;106(March):106712. doi:10.1016/j.foodcont.2019.106712
eon J, Kim JH, Lee CK, Oh CH, Song HJ. The antimicrobial activity of (-)-epigallocatehin-3-gallate and green tea extracts against Pseudomonas aeruginosa and Escherichia coli isolated from skin wounds. Ann Dermatol. 2014;26(5):564-569. doi:10.5021/ad.2014.26.5.564
Saquib SA, Alqahtani NA, Ahmad I, Kader MA, Al Shahrani SS, Asiri EA. Evaluation and comparison of antibacterial efficacy of herbal extracts in combination with antibiotics on periodontal pathobionts: An in vitro microbiological study. Antibiotics. 2019;8(3):1-12. doi:10.3390/antibiotics8030089
Hamilton-Miller JMT. Anti-cariogenic properties of tea (Camellia sinensis). J Med Microbiol. 2001;50(4):299-302. doi:10.1099/0022-1317-50-4-299
Mogana R, Wiart C. Potential of Scopoletin Isolated from Canarium patentinervium Miq . ( Burseraceae Kunth ). Evidence-based Complement Altern Med. 2013;2013:1-6.
Kang-Mu LEE, Wan-Seok KIM, Jeesun LIM, et al. Antipathogenic properties of green tea polyphenol epigallocatechin gallate at concentrations below the MIC against enterohemorrhagic escherichia coli O157:H7. J Food Prot. 2009;72(2):325-331. doi:10.4315/0362-028x-72.2.325
Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: A review. J Pharm Anal. 2016;6(2):71-79. doi:10.1016/j.jpha.2015.11.005
CLSI. CLSI M100-ED29: 2021 Performance Standards for Antimicrobial Susceptibility Testing, 30th Edition. Vol 40.; 2020.
Djordjevic D, Wiedmann M, McLandsborough LA. Microtiter plate assay for assessment of Listeria monocytogenes biofilm formation. Appl Environ Microbiol. 2002;68(6):2950-2958. doi:10.1128/AEM.68.6.2950-2958.2002
Eloff JN. A sensitive and quick microplate method to determine the minimal inhibitory concentration of plant extracts for bacteria. Planta Med. 1998;64(8):711-713. doi:10.1055/s-2006-957563
Leenhouts PW, C. Kalkman, Lam HJ. Leenhouts Dioecious , rarely monoecious trees the outer side by distinct , closed twigs , petioles with those in twigs mostly amphivasal mainly sclerenchymatic xylem , those in the petioles and petiolules collateral and consisting of abundant imparipinnat. Nat journals Ser. 1956;5(1):209-296. https://repository.naturalis.nl/pub/532548
Adnan M, Patel M, Deshpande S, et al. Effect of Adiantum philippense Extract on Biofilm Formation, Adhesion With Its Antibacterial Activities Against Foodborne Pathogens, and Characterization of Bioactive Metabolites: An in vitro-in silico Approach. Front Microbiol. 2020;11(April). doi:10.3389/fmicb.2020.00823
Mogana R, Bradshaw TD, Jin KT, Wiart C. In Vitro antitumor Potential of Canarium patentinervium Miq. Acad J Cancer Res. 2011;4(1):1-4.
Rizvi SMD, Shakil S, Haneef M. A simple click by click protocol to perform docking: Autodock 4.2 made easy for non-bioinformaticians. EXCLI J. 2013;12(November 2014):830-857.
Zhao Y, Qu Y, Tang J, Chen J, Liu J. Tea Catechin Inhibits Biofilm Formation of Methicillin-Resistant S. aureus. J Food Qual. 2021;2021. doi:10.1155/2021/8873091
Parvekar P, Palaskar J, Metgud S, Maria R, Dutta S. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of silver nanoparticles against Staphylococcus aureus . Biomater Investig Dent. 2020;7(1):105-109. doi:10.1080/26415275.2020.1796674
Mogana R, Adhikari A, Debnath S, et al. The antiacetylcholinesterase and antileishmanial activities of canarium patentinervium Miq. Biomed Res Int. 2014;2014(May). doi:10.1155/2014/903529
Hengge R. Targeting bacterial biofilms by the green tea polyphenol EGCG. Molecules. 2019;24(13):15-17. doi:10.3390/molecules24132403
Allouche A. Software News and Updates Gabedit — A Graphical User Interface for Computational Chemistry Softwares. J Comput Chem. 2012;32:174-182. doi:10.1002/jcc
Campo-Pérez V, Alcàcer-Almansa J, Julián E, Torrents E. A High-Throughput Microtiter Plate Screening Assay to Quantify and Differentiate Species in Dual-Species Biofilms. Microorganisms. 2023;11(9):2244. doi:10.3390/microorganisms11092244
.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.