Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review

Authors

  • Andrew Tumen University of Tennessee Health Science Center
  • Pranit N Chotai Vanderbilt University Medical Center
  • John Matthew William University of Tennessee Health Science Center
  • Adrianne Myers-Webb Division of Pediatric Surgery, University of Tennesse Health Science Center
  • Ramesh Krishnan Division of Neonatology, Department of Pediatrics, Regional One Health, University of Tennessee Health Science Center
  • James W Eubanks III Division of Pediatric Surgery, Department of General Surgery, University of Tennessee Health Science Center, Le Bonheur Children’s Hospital

DOI:

https://doi.org/10.52783/jns.v6.425

Keywords:

Neonatal perforated appendicitis, Neonatal appendicitis, Necrotizing enterocolitis, Localized NEC

Abstract

Neonatal appendicitis is a rare clinical entity associated with remarkable morbidity and mortality. Appen¬dicular perforation is common and the diagnosis is usually made intra-operatively. The causative etiology of neonatal perforated appendicitis (NPA) is a subject of debate and has not been elucidated. Although many etiologic theories exist, increasing evidence suggests a subset of NPA cases may represent a form of necrotizing enterocolitis (NEC) localized to the appendix. We herein present a review of the current litera¬ture to include cases of NPA attributed to localized NEC. A high index of clinical suspicion and early laparotomy are recommended.

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Author Biographies

Andrew Tumen, University of Tennessee Health Science Center

Medical Student

Pranit N Chotai, Vanderbilt University Medical Center

Resident, Department of Surgery

John Matthew William, University of Tennessee Health Science Center

Medical Student

Adrianne Myers-Webb, Division of Pediatric Surgery, University of Tennesse Health Science Center

Fellow, Pediatric Surgery

Ramesh Krishnan, Division of Neonatology, Department of Pediatrics, Regional One Health, University of Tennessee Health Science Center

Associate Professor, Division of Neonatology, Department of Pediatrics

James W Eubanks III, Division of Pediatric Surgery, Department of General Surgery, University of Tennessee Health Science Center, Le Bonheur Children’s Hospital

Associate Professor of Surgery and Pediatrics

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Published

2017-08-17

How to Cite

1.
Tumen A, Chotai PN, William JM, Myers-Webb A, Krishnan R, Eubanks III JW. Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review. J Neonatal Surg [Internet]. 2017Aug.17 [cited 2025Sep.20];6(3):60. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/425

Issue

Vol. 6 No. 3 (2017): Journal of Neonatal Surgery

Section

Review Article

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