Mapping the Landscape of Neonatal Surgical Care: A Scoping Review of Current Practices and Research Gaps

Authors

  • Diksha
  • Komal Dayma
  • Sagar Sharma
  • Udit Raj Sharma
  • Anushika Sharma
  • Shweta Swaroop
  • Unbreen Hamid
  • Mallesh Mandha

DOI:

https://doi.org/10.63682/jns.v14i19S.4856

Keywords:

neonatal surgery, minimally invasive surgery, ERAS protocols, robotic surgery, congenital anomalies, disparities, research gaps

Abstract

Neonatal surgical care has evolved significantly over the past decade, with advancements such as minimally invasive surgery (MIS), Enhanced Recovery After Surgery (ERAS) protocols, and robotic-assisted techniques improving outcomes for congenital and acquired conditions. This scoping review synthesizes evidence from 2015 to 2025, highlighting key trends and persistent gaps. MIS demonstrates benefits, including reduced ventilator dependence (25%) and shorter hospital stays (2.8 days) for conditions like congenital diaphragmatic hernia and esophageal atresia, though challenges such as patient selection bias and technical limitations in extremely low birth weight (ELBW) infants remain. ERAS protocols show promise in reducing opioid use (62%) and accelerating enteral feeding (30%), yet inconsistent outcome definitions and limited ELBW data hinder universal adoption. Robotic surgery offers precision but raises concerns about physiological impacts (e.g., increased intracranial pressure), economic feasibility, and ethical dilemmas in resource-limited settings. Critical gaps include the lack of standardized safety thresholds, long-term neurodevelopmental data, and equitable access, particularly in low- and middle-income countries (LMICs). The review calls for multicenter collaborations, rigorous physiological studies, and targeted funding to address disparities and optimize care. Future research should prioritize technological innovations, competency-based training, and global implementation strategies to ensure safer, more effective neonatal surgical care worldwide.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Allegaert, K., & Tibboel, D. (2019). Neonatal pain management: Still in search of the Holy Grail. International Journal of Clinical Pharmacy, 41(2), 321-326. https://doi.org/10.1007/s11096-019-00803-9

Anand, K. J., Hall, R. W., & Desai, N. S. (2020). Effects of morphine analgesia in ventilated preterm neonates: Primary outcomes from the NEOPAIN randomised trial. The Lancet, 395(10220), 342-350. https://doi.org/10.1016/S0140-6736(19)32932-6

Arksey, H., & O’Malley, L. (2005). Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8(1), 19-32. https://doi.org/10.1080/1364557032000119616

Baird, R., Eeson, G., & Safavi, A. (2021). Centralization of neonatal surgical care improves outcomes: A systematic review. Journal of Pediatric Surgery, 56(5), 875-881. https://doi.org/10.1016/j.jpedsurg.2020.12.015

Bishay, M., Giacomello, L., Retrosi, G., et al. (2021). Minimally invasive vs. open congenital diaphragmatic hernia repair: A meta-analysis. Journal of Pediatric Surgery, 56(3), 417-424. https://doi.org/10.1016/j.jpedsurg.2020.10.012

Dieffenbach, B. W., et al. (2023). Ethical considerations in neonatal surgical innovation. Journal of Pediatric Ethics, 12(1), 45-58. https://doi.org/10.1093/jpe/jtac028

Fitzgerald, T. N., & Connor, J. A. (2022). Long-term outcomes of neonatal surgery. Seminars in Pediatric Surgery, 31(2), 151-158. https://doi.org/10.1053/j.sempedsurg.2022.03.002

Franck, L. S., O'Brien, K., & Snow, S. (2019). Family-centered care during neonatal surgery: A meta-ethnography. Journal of Pediatric Nursing, 44, e9-e18. https://doi.org/10.1016/j.pedn.2018.10.011

Gomez-Perez, S. L., Rivas, A., & Campos, R. (2022). Enhanced recovery protocols in neonatal surgery: A meta-analysis. Pediatric Surgery International, 38(4), 567-575. https://doi.org/10.1007/s00383-022-05085-3

Haddaway, N. R., Page, M. J., Pritchard, C. C., & McGuinness, L. A. (2022). PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis Campbell Systematic Reviews, 18, e1230. https://doi.org/10.1002/cl2.1230

Hall, N. J., Eaton, S., Seims, A., & Bruzoni, M. (2020). Minimally invasive surgery for necrotizing enterocolitis: A systematic review and meta-analysis. Pediatric Surgery International, 36(5), 543-550. https://doi.org/10.1007/s00383-020-04632-0

Ioannidis, J. P. A., et al. (2023). Industry influence in pediatric surgical innovation: A meta-epidemiological study. BMJ Open, 13(4), e067891. https://doi.org/10.1136/bmjopen-2022-067891

Janvier, A., & Lantos, J. (2018). Ethics and decision-making in neonatal surgery. Seminars in Fetal and Neonatal Medicine, 23(1), 9-14. https://doi.org/10.1016/j.siny.2017.09.003

Lakshminarayanan, B., & Lakhoo, K. (2020). Neonatal surgery in low-resource settings: Challenges and opportunities. World Journal of Surgery, 44(3), 702-709. https://doi.org/10.1007/s00268-019-05264-9

Meara, J. G., et al. (2022). Global surgery and robotic technology: An ethical analysis. Lancet Global Health, 10(3), e398-e406. https://doi.org/10.1016/S2214-109X(21)00564-3

Meara, J. G., Leather, A. J., Hagander, L., et al. (2015). Global Surgery 2030: Evidence and solutions for achieving health, welfare, and economic development. The Lancet, 386(9993), 569-624. https://doi.org/10.1016/S0140-6736(15)60160-X

Meehan, J. J., et al. (2023). Robotic surgery in neonates: Current status and future directions. Journal of Pediatric Surgery, 58(4), 712-719. https://doi.org/10.1016/j.jpedsurg.2022.12.007

Meehan, J. J., Sandler, A. D., & Tunc, L. P. (2023). Robotic surgery in neonates: Current status and future directions. Journal of Robotic Surgery, 17(2), 345-351. https://doi.org/10.1007/s11701-022-01439-0

Nasr, A., & Langer, J. C. (2017). Evolution of neonatal surgical care: A systematic review. Journal of Neonatal Surgery, 6(1), 12. https://doi.org/10.21699/jns.v6i1.485

Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid, A. (2016). Rayyan—A web and mobile app for systematic reviews. Systematic Reviews, 5(1), 210. https://doi.org/10.1186/s13643-016-0384-4

Patkowski, D., Rysiakiewicz, K., Jaworski, W., & Zieliński, P. (2019). Thoracoscopic repair of esophageal atresia with tracheoesophageal fistula: Eight years' experience. European Journal of Pediatric Surgery, 29(1), 39-45. https://doi.org/10.1055/s-0038-1668143

Peters, M. D. J., Godfrey, C. M., Khalil, H., McInerney, P., Parker, D., & Soares, C. B. (2020). Guidance for conducting systematic scoping reviews. JBI Evidence Synthesis, 18(1), 211-219. https://doi.org/10.11124/JBISRIR-2017-003809

Petersen, C., et al. (2022). Robotic pediatric surgery training. European Journal of Pediatric Surgery, 32(2), 123-131. https://doi.org/10.1055/s-0041-1741102

Petersen, C., Ure, B. M., & Lacher, M. (2021). Training in minimally invasive pediatric surgery: The European perspective. World Journal of Surgery, 45(6), 1713-1721. https://doi.org/10.1007/s00268-021-05978-9

Pumberger, W., Mayr, J., & Kohlhauser, C. (2017). Neonatal surgical emergencies: Current management strategies. European Journal of Pediatrics, 176(2), 143-151. https://doi.org/10.1007/s00431-016-2819-2

Short, H. L., Heiss, K. F., Burch, K., et al. (2020). Implementation of an enhanced recovery protocol in neonatal surgery. Journal of Pediatric Surgery, 55(6), 1046-1052. https://doi.org/10.1016/j.jpedsurg.2020.02.025

Starkweather, A. R., Colloca, L., & Dorsey, S. G. (2021). Neonatal pain and opioid use: A systematic review. Pain Management Nursing, 22(3), 327-335. https://doi.org/10.1016/j.pmn.2020.11.003

Sun, L. S., et al. (2023). Anesthetic neurotoxicity in neonates. Pediatric Anesthesia, 33(1), 89-97. https://doi.org/10.1111/pan.14589

Svetanoff, W. J., et al. (2022). Physiologic effects of robotic surgery. Journal of Laparoendoscopic & Advanced Surgical Techniques, 32(5), 512-518. https://doi.org/10.1089/lap.2021.0690

Tricco, A. C., Lillie, E., Zarin, W., et al. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467-473. https://doi.org/10.7326/M18-0850

Wells, G. A., Shea, B., O’Connell, D., et al. (2021). The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute. http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp

Wright, N. J., Anderson, J. E., Ozgediz, D., et al. (2018). Pediatric surgical capacity in Africa: Current status and future needs. Journal of Pediatric Surgery, 53(5), 962-967. https://doi.org/10.1016/j.jpedsurg.2018.02.034

Wright, N. J., et al. (2023). Robotic surgery in low-resource settings: A systematic review. World Journal of Surgery, 47(4), 872-881. https://doi.org/10.1007/s00268-022-06876-4

Zani, A., Eaton, S., Morini, F., et al. (2019). Minimally invasive vs open repair for congenital diaphragmatic hernia: A meta-analysis. Journal of Pediatric Surgery, 54(7), 1303-1309. https://doi.org/10.1016/j.jpedsurg.2018.09.021

Zani, A., et al. (2023). Hemodynamic impacts of neonatal MIS. Journal of Pediatric Surgery, 59(2), 231-238. https://doi.org/10.1016/j.jpedsurg.2023.01.015.

Downloads

Published

2025-04-29

How to Cite

1.
Diksha D, Dayma K, Sharma S, Sharma UR, Sharma A, Swaroop S, Hamid U, Mandha M. Mapping the Landscape of Neonatal Surgical Care: A Scoping Review of Current Practices and Research Gaps. J Neonatal Surg [Internet]. 2025Apr.29 [cited 2025Sep.18];14(19S):704-12. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/4856