SYNERGIZING AI, IOT, AND NANOTECHNOLOGY FOR INNOVATIVE MEDICAL DIAGNOSTICS AND THERAPEUTIC SOLUTIONS

Authors

  • Sahil Kumar
  • Rabia Afzaal
  • Riffat Bibi
  • Anirudh Gupta
  • Avrina Kartika Ririe
  • Hamad Mohammad Ali Duleh
  • Rama Krishna Reddy Guduru
  • Sudhair Abbas Bangash

DOI:

https://doi.org/10.63682/jns.v14i20S.5019

Keywords:

AI, Internet of Things, Nanotechnology, Health Care, Diagnosis, Health, Adoption Issues, Research Methodology

Abstract

Background: The three technologies mentioned above, Artificial Intelligence (AI), the Internet of Things (IoT), and Nanotechnology, are still believed to transform healthcare diagnosis and therapies in the future. These technologies promise to improve accuracy, workflow, and patient-centered practices, but barriers to implementing them persist: privacy, regulation, and technical skills.

Objective: This research thus sought to establish the level of awareness and understanding of the professionals concerning AI, IoT, & nanotechnology in Healthcare; The level of readiness of these intelligent technologies in the healthcare delivery systems; The probable probability level of how widely spread across the health diagnostic and healing solutions the AI, IoT & nanotechnology may likely penetrate the field.

Methods: A cross-sectional research design was adopted for this study because the study targeted a large population with a large sample size of 250 respondents who are health care practitioners, researchers, and information technology experts. Quantitative data were used to describe the findings with frequencies and percentages. In contrast, inferential data (Regression & Chi-square tests) were used to test adoption likelihood, age, and familiarity hypotheses. Hypothesis testing using normality and reliability tests was used to confirm the data.

Results: Most respondents had a high awareness of AI and IoT and a positive attitude towards its ability to improve diagnostics. The reliability of the questionnaire was determined by Cronbach's Alpha, which was high (1. 0). Normality tests showed that some variables, like customers' Confidence in tackling healthcare issues, were not normally distributed. The main issues revealed include privacy, legal issues, and resource constraints, especially technical skills. Self-confidence and

 

readiness to act were also age-dependent, with 18 – 29-year-old photographers showing varied self-confidence compared to their older colleagues.


Conclusion: All three innovation systems, AI, IoT, and nanotechnology, are more appreciated in the context of Healthcare, and there is a high willingness to change medical diagnosis and therapy. However, areas such as privacy, regulation, and expertise form some of the barriers that need to be resolved to enable the penetration of the technology to deeper and more parts of society. Ultimately, this research shows the need for continued and focused scholarship and educational efforts geared toward successfully mainstreaming these technologies in healthcare

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Anurogo, D., & Hidayat, N. A. (2023). THE ART OF TELEVASCULOBIOMEDICINE 5.0: Nas Media Pustaka.

Araujo-Filho, I., & do Rêgo, A. C. M. (2024). Nanotechnology and Immunetherapy: reduction of hepatotoxicity and anti-antineoplastic efficiency: Nanotechnology and Immunetherapy. JOURNAL OF SURGICAL AND CLINICAL RESEARCH, 15(1), 59-78.

Augustine, R., Al Mamun, A., Hasan, A., Salam, S. A., Chandrasekaran, R., Ahmed, R., & Thakor, A. S. (2021). Imaging cancer cells with nanostructures: Prospects of nanotechnology driven non-invasive cancer diagnosis. Advances in Colloid and Interface Science, 294, 102457.

Avdan, G., & Onal, S. (2024). Lean Thinking in Healthcare 5.0 Technologies: An Exploratory Review. Paper presented at the Proceedings of the 9th North American Conference on Industrial Engineering and Operations Management.

Baranowska-Wójcik, E., & Szwajgier, D. (2020). Alzheimer's disease: Review of current nanotechnological therapeutic strategies. Expert review of neurotherapeutics, 20(3), 271-279.

Batool, A., Menaa, F., Uzair, B., Khan, B. A., & Menaa, B. (2020). Progress and prospects in translating nanobiotechnology in medical theranostics. Current Nanoscience, 16(5), 685-707.

Bhatia, S. N., Chen, X., Dobrovolskaia, M. A., & Lammers, T. (2022). Cancer nanomedicine. Nature Reviews Cancer, 22(10), 550-556.

Carvalho, C. R., Silva-Correia, J., Oliveira, J. M., & Reis, R. L. (2019). Nanotechnology in peripheral nerve repair and reconstruction. Advanced Drug Delivery Reviews, 148, 308-343.

Chaudhary, V., Vasistha, S., & Rai, M. P. (2024). Nanobiotechnology: an Applicable Approach for Sustainable Future. Emerging Sustainable Nanomaterials for Biomedical Applications, 243-268.

Chen, H., Luo, K., Xie, C., & Zhou, L. (2024). Nanotechnology of carbon dots with their hybrids for biomedical applications: A review. Chemical Engineering Journal, 496, 153915.

Chen, S., Tong, X., Huo, Y., Liu, S., Yin, Y., Tan, M. L., . . . Ji, W. (2024). Piezoelectric Biomaterials Inspired by Nature for Applications in Biomedicine and Nanotechnology. Advanced Materials, 2406192.

Chen, W., Schilperoort, M., Cao, Y., Shi, J., Tabas, I., & Tao, W. (2022). Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis. Nature Reviews Cardiology, 19(4), 228-249.

Cheng, H., Xu, H., Peng, B., Huang, X., Hu, Y., Zheng, C., & Zhang, Z. (2024). Illuminating the future of precision cancer surgery with fluorescence imaging and artificial intelligence convergence. NPJ Precision Oncology, 8(1), 196.

Cheng, Y., Cai, S., Wu, H., Pan, J., Su, M., Wei, X., . . . Chu, C. (2024). Revolutionizing eye care: the game-changing applications of nano-antioxidant in ophthalmology. Nanoscale.

Chopra, H., Mohanta, Y. K., Rauta, P. R., Ahmed, R., Mahanta, S., Mishra, P. K., . . . Othman, B. (2023). An insight into advances in developing nanotechnology-based therapeutics, drug delivery, diagnostics, and vaccines: multidimensional applications in tuberculosis disease management. Pharmaceuticals, 16(4), 581.

Chude-Okonkwo, U. K., Paul, B. S., & Vasilakos, A. V. (2022). Enabling precision medicine via contemporary and future communication technologies: A survey. Ieee Access, 11, 21210-21240.

Craig, M., Jenner, A. L., Namgung, B., Lee, L. P., & Goldman, A. (2020). Engineering in medicine to address the challenge of cancer drug resistance: from micro-and nanotechnologies to computational and mathematical modeling. Chemical Reviews, 121(6), 3352-3389.

Damane, B. P., Kgokolo, M. C., Gaudji, G. R., Blenman, K. R., & Dlamini, Z. (2023). Integration of cyber-physical systems in the advancement of Society 5.0 healthcare management. In Society 5.0 and Next Generation Healthcare: Patient-Focused and Technology-Assisted Precision Therapies (pp. 201-221): Springer.

Gopikrishnan, M., & Haryini, S. (2024). Emerging strategies and therapeutic innovations for combating drug resistance in Staphylococcus aureus strains: A comprehensive review. Journal of Basic Microbiology, 64(5), 2300579.

Han, J., Choi, Y. J., & Kang, S. K. (2024). Synergistic Strategies of Biomolecular Transport Technologies in Transdermal Healthcare Systems. Advanced Healthcare Materials, 2401753.

Hülck, S. (2024). Nanotechnology-based analytics 4.0: an approach for real-time spectroscopic monitoring and rapid detection of SARS CoV-2. Paper presented at the High-Speed Biomedical Imaging and Spectroscopy IX.

Jiang, J., Cui, X., Huang, Y., Yan, D., Wang, B., Yang, Z., . . . Liu, G. (2024). Advances and Prospects in Integrated Nano-oncology. Nano Biomedicine & Engineering, 16(2).

Kahlem, P., Berenger-Molins, P., & Akbulut, H. (2024). Theranostics-enabling high-tech centers: the value of centralizing resources in countries in development. F1000Research, 13, 283.

Kaur, I., Behl, T., Aleya, L., Rahman, H., Kumar, A., Arora, S., & Bulbul, I. J. (2021). Artificial intelligence is a fundamental tool in the management of infectious diseases and its current implementation in the COVID-19 pandemic. Environmental Science and Pollution Research, 28(30), 40515-40532.

Khondakar, K. R., Tripathi, D., Mazumdar, H., Ahuja, K., & Kaushik, A. (2024). Tailored MXene and Graphene as Efficient Telemedicine Platforms for Personalized Health Wellness. Materials Advances.

Kim, K., & Park, M.-H. (2024). Advancing Cancer Treatment: Enhanced Combination Therapy through Functionalized Porous Nanoparticles. Biomedicines, 12(2), 326.

Kokabi, M., Tahir, M. N., Singh, D., & Javanmard, M. (2023). Advancing Healthcare: synergizing biosensors and machine learning for early cancer diagnosis. Biosensors, 13(9), 884.

Kudruk, S., Forsyth, C. M., Dion, M. Z., Hedlund Orbeck, J. K., Luo, J., Klein, R. S., . . . Stegh, A. H. (2024). Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy. Proceedings of the National Academy of Sciences, 121(8), e2306973121.

Kumar, N. S. V., Meghana, I. S., Pavani, P., Sampath Kumar, N., & Chintagunta, A. D. (2024). Role of Nanotechnology and Artificial Intelligence (AI) in Waste Management. In Recent Advances in Bioprocess Engineering and Bioreactor Design (pp. 263-286): Springer.

Landowski, L. M., Niego, B. E., Sutherland, B. A., Hagemeyer, C. E., & Howells, D. W. (2020). Applications of nanotechnology in the diagnosis and therapy of stroke. Paper presented at the Seminars in thrombosis and hemostasis.

Liu, J., Wu, J., Chen, T., Yang, B., Liu, X., Xi, J., . . . Li, Z. (2024). Enhancing X‐Ray Sensitization with Multifunctional Nanoparticles. Small, 2400954.

Liu, J., Yuan, S., Bremmer, A., & Hu, Q. (2024). Convergence of Nanotechnology and Bacteriotherapy for Biomedical Applications. Advanced Science, 11(16), 2309295.

Liu, T., Liu, L., Li, L., & Cai, J. (2023). Exploiting targeted nanomedicine for surveillance, diagnosis, and treatment of hepatocellular carcinoma. Materials Today Bio, 22, 100766.

Malik, S., Muhammad, K., & Waheed, Y. (2023). Emerging applications of nanotechnology in Healthcare and medicine. Molecules, 28(18), 6624.

Mishra, A., Singh, P. K., Chauhan, N., Roy, S., Tiwari, A., Gupta, S., . . . Mishra, P. (2024). Emergence of integrated biosensing-enabled digital healthcare devices. Sensors & Diagnostics, 3(5), 718-744.

Mitra, S., Mishra, S., Mohapatra, R. K., Pradhan, M. K., & Azam, M. Prospects and Future Scope of Smart Drug Delivery Systems: A Critical Perspective. In Smart Micro-and Nanomaterials for Drug Delivery (pp. 372-414): CRC Press.

Mohammadi, A. T., Amini, K., Mojtahedzadeh, M., Arjipour, M., Mehrpooya, M., Mahdilou, M., & Ghanbarzadeh, E. (2024). Exploring Boundless Horizons: Medicine and Pharmacy: Nobel Sciences.

Mohanta, Y. K., Chakrabartty, I., Mishra, A. K., Chopra, H., Mahanta, S., Avula, S. K., . . . Mohanta, T. K. (2023). Nanotechnology in combating biofilm: A smart and promising therapeutic strategy. Frontiers in Microbiology, 13, 1028086.

Naik, G. G., & Jagtap, V. A. Nano TransMed.

Naik, G. G., & Jagtap, V. A. (2024). Two Heads Are Better than One: Unravelling the Potential Impact of Artificial Intelligence in Nanotechnology. Nano TransMed, 100041.

Omidian, H., & Mfoafo, K. (2023). Exploring the potential of nanotechnology in pediatric Healthcare: advances, challenges, and future directions. Pharmaceutics, 15(6), 1583.

Pan, Y., Xue, X., & Liang, X. J. (2024). Nanotechnology‐Empowered Combination Cancer Immunotherapies: Mechanisms, Synergies, and Perspectives. Advanced NanoBiomed Research, 4(4), 2300129.

Pandey, A., Singh, B. K., Gayathiri, E., Balasubramani, S., Duraisamy, S. M., Kothari, A., & Patel, D. K. (2024). Nanoparticles in Biomedical and Clinical Research: A Current Perspective and Future Implications. In Nanomaterials for Biomedical and Bioengineering Applications (pp. 415-457): Springer.

Qamar, S. U. R. (2021). Nanocomposites: Potential therapeutic agents for the diagnosis and treatment of infectious diseases and cancer. Colloid and Interface Science Communications, 43, 100463.

Qureshi, M. A., Khan, M. Y., Imran, A., Maqsood, Q., Hussain, N., & Ali, S. W. (2024). Revolutionizing Breast Cancer Care: Cutting-Edge Breakthroughs and Future Frontiers in Precision Medicine. In: Springer.

Rastogi, A., Singh, A., Naik, K., Mishra, A., Chaudhary, S., Manohar, R., & Parmar, A. S. (2022). A systemic review on liquid crystals, nanoformulations, and their application for detection and treatment of SARS–CoV–2 COVID–19). Journal of Molecular Liquids, 362, 119795.

Rebelo, R., Barbosa, A. I., Caballero, D., Kwon, I. K., Oliveira, J. M., Kundu, S. C., . . . Correlo, V. M. (2019). 3D biosensors in advanced medical diagnostics of high mortality diseases. Biosensors and Bioelectronics, 130, 20-39.

Ren, S., Xu, Y., Dong, X., Mu, Q., Chen, X., Yu, Y., & Su, G. (2024). Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges. Journal of Nanobiotechnology, 22(1), 431.

Roy, I., Krishnan, S., Kabashin, A. V., Zavestovskaya, I. N., & Prasad, P. N. (2022). Transforming nuclear medicine with nano radiopharmaceuticals. ACS nano, 16(4), 5036-5061.

Saleh, Z., Jaber, W., Jaber, A., Cheble, E., Bechelany, M., Hijazi, A., . . . Ibrahim, G. M. (2024). Utilizing AI and Nanotechnology Solutions to Propel Progress in Cancer Diagnostics, Therapeutics, and Integrated Theranostics. In Artificial Intelligence in the Age of Nanotechnology (pp. 114-135): IGI Global.

Sandbhor, P., Palkar, P., Bhat, S., John, G., & Goda, J. S. (2024). Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy. Nanoscale.

Shehu, I. A., Musa, M. K., Datta, A., & Verma, A. (2022). Application of nanotechnology in COVID-19 infection: Findings and limitations. Journal of Nanotheranostics, 3(4), 203-232.

Shi, Y., Chen, L., Zhu, M., & Zhao, Y. (2022). The Future of Nanomedicine. In Nanomedicine (pp. 1-28): Springer.

Singh, A. B., Khandelwal, C., & Dangayach, G. S. (2024). Revolutionizing healthcare materials: Innovations in processing, advancements, and challenges for enhanced medical device integration and performance. Journal of Micromanufacturing, 25165984241256234.

Singh, H., & Kaur, K. (2023). Role of nanotechnology in research fields: Medical sciences, military & tribology-A review on recent advancements, grand challenges and perspectives. Materials Today: Proceedings.

Sonakpuri, J., Niranjan, P., Dixit, V., & Savita, S. NANOTECHNOLOGY IN ANTIMICROBIAL THERAPY: ENHANCING THE ARSENAL AGAINST RESISTANT MICROORGANISMS. Nanotechnology, 14, 16.

Sousa, F., Ferreira, D., Reis, S., & Costa, P. (2020). Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources. Pharmaceuticals, 13(9), 248.

Taha, B. A., Ahmed, N. M., Talreja, R. K., Haider, A. J., Al Mashhadany, Y., Al-Jubouri, Q., . . . Kaushik, A. (2024). Synergizing Nanomaterials and Artificial Intelligence in Advanced Optical Biosensors for Precision Antimicrobial Resistance Diagnosis. ACS Synthetic Biology.

Unnithan, D., Sartaj, A., Iqubal, M. K., Ali, J., & Baboota, S. (2024). A neoteric annotation on the advances in combination therapy for Parkinson's disease: nanocarrier-based combination approach and future anticipation. Part II: nanocarrier design and development in focus. Expert opinion on drug delivery, 21(3), 437-456.

Verma, A., Sharma, P. K., & Singh, A. (2024). Nanomedicine: Transforming Healthcare through Precision, Theranostics, and Future Frontiers. Lipid-Based Nanocarriers for Drug Delivery, 111.

Wang, C., Fan, W., Zhang, Z., Wen, Y., Xiong, L., & Chen, X. (2019). Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy. Advanced Materials, 31(49), 1904329.

Wang, J., Yu, Y., & Li, Y. (2024). Molecular Modeling in Drug Delivery. Exploring Computational Pharmaceutics: AI and Modeling in Pharma 4.0, 293.

Wang, J., Zhao, W., Zhang, Z., Liu, X., Xie, T., Wang, L., . . . Zhang, Y. (2024). A journey of challenges and victories: a bibliometric worldview of nanomedicine since the 21st century. Advanced Materials, 36(15), 2308915.

Wang, W., Liu, L., Zhu, J., Xing, Y., Jiao, S., & Wu, Z. (2024). AI-Enhanced Visual-Spectral Synergy for Fast and Ultrasensitive Biodetection of Breast Cancer-Related miRNAs. ACS nano, 18(8), 6266-6275.

Wang, Y., Yung, P., Lu, G., Liu, Y., Ding, C., Mao, C., . . . Tuan, R. S. (2024). Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface. Advanced Materials, 2401334.

Wasilewski, T., Kamysz, W., & Gębicki, J. (2024). AI-Assisted Detection of Biomarkers by Sensors and Biosensors for Early Diagnosis and Monitoring. Biosensors, 14(7).

Xiao, Y., Zhong, L., Liu, J., Chen, L., Wu, Y., & Li, G. (2024). Progress and application of intelligent nanomedicine in urinary system tumors. Journal of Pharmaceutical Analysis, 100964.

Yadav, S. K., & Jayaramulu, K. (2024). Role of quantum technology and artificial intelligence for nano-enabled microfluidics. In Next-Generation Smart Biosensing (pp. 189-208): Elsevier.

Yayehrad, A. T., Siraj, E. A., Wondie, G. B., Alemie, A. A., Derseh, M. T., & Ambaye, A. S. (2021). Could nanotechnology help to end the fight against COVID-19? Review of current findings, challenges, and future perspectives. International Journal of Nanomedicine, 5713-5743.

Zhang, Y., Wei, G., Liu, W., Li, T., Wang, Y., Zhou, M., . . . Wei, H. (2024). Nanozymes for nanohealthcare. Nature Reviews Methods Primers, 4(1), 36..

...

Downloads

Published

2025-05-02

How to Cite

1.
Kumar S, Afzaal R, Bibi R, Gupta A, Ririe AK, Ali Duleh HM, Guduru RKR, Bangash SA. SYNERGIZING AI, IOT, AND NANOTECHNOLOGY FOR INNOVATIVE MEDICAL DIAGNOSTICS AND THERAPEUTIC SOLUTIONS. J Neonatal Surg [Internet]. 2025May2 [cited 2025Sep.23];14(20S):334-45. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/5019

Most read articles by the same author(s)

<< < 1 2