Evaluating Social and Clinical Value in Health Interventions: A Cross-Sectional Study of Vaccine Uptake in Low-Income Communities

Authors

  • Dipak Sethi
  • Harsha Teja Suvvada
  • Shayani Bose
  • Sukanta Bandyopadhyay

Keywords:

Vaccine uptake, low-income communities, social value, clinical value, health literacy, healthcare access, socioeconomic factors

Abstract

Low-income populations still present with low vaccine utilization due to factors such as poor access to healthcare, low health literacy, and perceived social and clinical utility of vaccines. This research aims to identify factors that influence vaccination behaviors to understand how to enhance coverage in these regions. A self-administered questionnaire was used to evaluate the participants’ vaccination history and perception of the utility of immunization among 500 adults residing in targeted low-income communities. Descriptive and regression analyses were used to establish the predictors of vaccine uptake.  Results showed an overall uptake rate of 42%, with slightly higher rates among females (45%) than males (39%). Education and income levels were important factors: participants with post-secondary education reported a 55% vaccination rate, while those above the poverty line had a 50% rate. Notably, social and clinical perceptions of the vaccine were significantly related to the uptake of the vaccine, as people with positive perceptions of vaccination health and community benefits were likely to be vaccinated. The results imply that increasing health literacy, increasing the availability of healthcare services, and raising awareness about community-based education could greatly improve the uptake of vaccines. Specifically, an intervention known as ‘client tracking and tracing’ can directly refer susceptible population groups to vaccinating facilities to increase immunity coverage among disadvantaged persons who might be discouraged from taking vaccines due to one reason or the other

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References

Barron, G. C., Laryea-Adjei, G., Vike-Freiberga, V., Abubakar, I., Dakkak, H., Devakumar, D., ... & Karadag, O. (2022). Safeguarding people living in vulnerable conditions in the COVID-19 era through universal health coverage and social protection. The Lancet Public Health, 7(1), e86-e92.

Eiden, A. L., Hartley, L., Garbinsky, D., Saande, C., Russo, J., Hufstader Gabriel, M., ... & Bhatti, A. (2024). Adult vaccination coverage in the United States: A database analysis and literature review of improvement strategies. Human Vaccines & Immunotherapeutics, 20(1), 2381283.

Fekadu, H., Mekonnen, W., Adugna, A., Kloos, H., & Hailemariam, D. (2024). Barriers to equitable healthcare services for under-five children in Ethiopia: a qualitative exploratory study. BMC Health Services Research, 24(1), 613.

Fleary, S. A., Joseph, P., & Pappagianopoulos, J. E. (2018). Adolescent health literacy and health behaviors: A systematic review. Journal of Adolescence, 62, 116-127.

Fu, L. Y., Bonhomme, L. A., Cooper, S. C., Joseph, J. G., & Zimet, G. D. (2014). Educational interventions to increase HPV vaccination acceptance: a systematic review. Vaccine, 32(17), 1901-1920.

Gautam, N., Dessie, G., Rahman, M. M., & Khanam, R. (2023). Socioeconomic status and health behavior in children and adolescents: a systematic literature review. Frontiers in Public Health, 11, 1228632.

Jarrett, C., Wilson, R., O’Leary, M., Eckersberger, E., & Larson, H. J. (2015). Strategies for addressing vaccine hesitancy–A systematic review. Vaccine, 33(34), 4180-4190.

KB, M., Nayar, S. A., & PV, M. (2022). Vaccine and vaccination as a part of human life: given Covid‐19. Biotechnology Journal, 17(1), 2100188.

Larson, H. J., De Figueiredo, A., Xiahong, Z., Schulz, W. S., Verger, P., Johnston, I. G., ... & Jones, N. S. (2016). The state of vaccine confidence 2016: global insights through a 67-country survey. EBioMedicine, 12, 295-301.

MacDonald, N. E. (2015). Vaccine hesitancy: Definition, scope and determinants. Vaccine, 33(34), 4161-4164.

McLeroy, K. R., Bibeau, D., Steckler, A., & Glanz, K. (1988). An ecological perspective on health promotion programs. Health Education Quarterly, 15(4), 351-377.

Nandi, A., & Shet, A. (2020). Why vaccines matter: understanding the broader health, economic, and child development benefits of routine vaccination. Human vaccines & immunotherapeutics, 16(8), 1900-1904.

Poland, C. M., & Ratishvili, T. (2022). Vaccine hesitancy and health care providers: using the preferred cognitive styles and decision-making model and empathy tool to make progress. Vaccine: X, 11, 100174.

Rader, B., Astley, C. M., Sewalk, K., Delamater, P. L., Cordiano, K., Wronski, L., ... & Brownstein, J. S. (2022). Spatial modeling of vaccine deserts as barriers to controlling SARS-CoV-2. Communications Medicine, 2(1), 141.

Rodrigues, C. M., & Plotkin, S. A. (2020). Impact of vaccines; health, economic and social perspectives. Frontiers in microbiology, 11, 1526.

Sahu, G., Kumari, P., & Goyal, A. K. (2024). Vaccines and sera. In Molecular Pharmaceutics and Nano Drug Delivery (pp. 15-62). Academic Press.

Schoch-Spana, M., Brunson, E., Long, R., Ravi, S., Ruth, A., & Trotochaud, M. (2020). The public’s role in COVID-19 vaccination: planning recommendations informed by design thinking and the social, behavioral, and communication sciences. Johns Hopkins Center for Health Security.

Suneja, N., & Bose, K. (2022). Communicating COVID: Learnings and Way Forward. In Health Dimensions of COVID-19 in India and Beyond (pp. 289-308). Singapore: Springer Nature Singapore.

Taha, M. K., Martinon-Torres, F., Köllges, R., Bonanni, P., Safadi, M. A. P., Booy, R., ... & Abitbol, V. (2022). Equity in vaccination policies to overcome social deprivation as a risk factor for invasive meningococcal disease. Expert review of vaccines, 21(5), 659-674.

Valentine, N. B., & Bonsel, G. J. (2016). Exploring models for the roles of health systems’ responsiveness and social determinants in explaining universal health coverage and health outcomes. Global Health Action, 9(1), 29329.

Wilson, L., Rubens-Augustson, T., Murphy, M., Jardine, C., Crowcroft, N., Hui, C., & Wilson, K. (2018). Barriers to immunization among newcomers: a systematic review. Vaccine, 36(8), 1055-1062

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Published

2025-05-09

How to Cite

1.
Sethi D, Suvvada HT, Bose S, Bandyopadhyay S. Evaluating Social and Clinical Value in Health Interventions: A Cross-Sectional Study of Vaccine Uptake in Low-Income Communities. J Neonatal Surg [Internet]. 2025May9 [cited 2025Oct.18];14(7):220-8. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/5482