Hypersensitivity Assessment of Non-Carious Cervical Lesions After Treatment with Different Desensitizing Protocols: A Randomized Clinical Trial
Keywords:
varnish, light-cured desensitizer,, sensitivity, dentin sensitivity, dentin hypersensitivity, visual analog scale, VAS, sylc powder, sylc air polishing, bioactive glass, and randomized controlled studyAbstract
Trial design This is a three-arm, parallel-group, randomized, controlled, superiority, double-blinded experiment with a 1:1:1 allocation ratio. Using the Visual Analogue Scale (VAS scale), this study compared the clinical efficacy of fluoride varnish and light-cured resin-based desensitizer and bioactive glass powder in treating dentin hypersensitivity (DH) in adults with cervical non-carious lesions over a six-month follow-up period. Methods 75 individuals with non-carious cervical lesions (NCCL) who met the predefined inclusion and exclusion criteria were randomly assigned to one of three parallel groups (n=25) based on the treatment they received. Group 1 received fluoride varnish for their NCCL, Group 2 received "Sylc® dry powder" with the help of a "AquaCareTM Twin" air abrasion unit, and Group 3 received light-cured desensitizer agent SHIELD FORCE PLUS (Tokuyama). All participants had a pre-operative hypersensitivity test, and only those patients whose VAS score indicated a level of discomfort equal to or more than five were accepted into the study. Using an air blast with a standardized length and pressure, hypersensitivity was evaluated both immediately following treatment and three months later. The VAS's ordinal data were represented by median and range values. The Friedman test of repeated measures and the Mann Whitney U test were used for intragroup and intergroup comparisons, respectively. The significance criterion was set at P ≤0.05 for each test. Results The application of fluoride varnish caused the considerably highest VAS, followed by the application of sylc powder air polishing and light-cured desensitizer. The overall effect of the three interventions revealed a statistically significant difference in the VAS score (p<0.001). Even while there was a notable statistically significant difference between the three interventions' baseline VAS scores within the two follow-up intervals, there was no statistically significant difference in the baseline records within each follow-up interval.
Conclusions and Clinical relevance. A quick and long-lasting solution for NCCL hypersensitivity is a light-cured desensitizing agent. Conversely, fluoride varnish remains an effective treatment for dentin hypersensitivity, but it is unreliable when used only once.
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West N. X. (2008). Dentine hypersensitivity: preventive and therapeutic approaches to treatment. Periodontology 2000. Vol.48, pp.:31-41.
Zeola F. L., Soares P. V., Cruz J. C. (2019). Prevalence of dentin hypersensitivity: Systematic review and meta-analysis. Journal of Dentistry. Vol.81, pp.:1-6.
West N, Hooper S., O’Sullivan D., Hughes N., North M., Macdonald E., Davies M., Claydon N. (2012). In situ randomized trial investigating abrasive effects of two desensitising toothpastes on dentine with acidic challenge prior to brushing. Journal of Dentistry. Vol.40, pp.:77–85.
Rapp R., Avery J.K., Recoter R.A. (1957). A study of the distribution of nerves in human teeth. Journal of the Canadian Dental Association. Vol.23, pp.:447–453.
Frank R.M., Steuer P. (1988). Transmission electron microscopy of the human odontoblast process in peripheral root dentine. Archives of Oral Biology. Vol.33, pp.:91–98.
Rapp R., Avery J.K., Strachen D.S. (1968). Possible role of the aceylcholinesterase in neural conduction within the dental pulp. In: Finn SB (ed) Biology of dental pulp organ. University of Alabama Press, Birmingham. p 309.
Närhi M.V.O. (1985). Dentine sensitivity: a review. Juornale de Biologie Buccale. Vol.13, pp.:75–96.
Hirvonen T.J., Närhi M.V.O., Hakumaki M.O.K. (1984). The excitability of dog pulp nerves in relation to the condition of dentine surface. Journal of Endodontics. Vol.10, pp.:294–298.
Gysi A. (1900). An attempt to explain the sensitiveness of dentin. British Dental Journal. Vol.43, pp.:865–868
Brännström M. (1966). The sensitivity of dentine. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. Vol.21, pp.:517–526.
Dowell P., Addy M. (1983). Dentine hypersensitivity ‐ A review: Aetiology, symptoms and theories of pain production. Journal of clinical periodontology. Vol.10, pp.: 341-350.
Clark D., Levin L. (2016). Non-surgical management of tooth hypersensitivity. International Dental Journal. Vol.66, issue (5), pp.: 249-256.
Walters P. A. (2005). Dentinal hypersensitivity: a review. The Journal of Contemporary Dental Practice. Vol.6, issue (2), pp.: 107-117.
Molina A., García-Gargallo M., Montero E., Tobías A., Sanz M.and Martín C. (2017). Clinical efficacy of desensitizing mouthwashes for the control of dentin hypersensitivity and root sensitivity: a systematic review and meta-analysis. International Journal of Dental Hygiene. Vol.15, issue (2), pp.: 84- 94.
Montazerian M. and Zanotto E. D. (2017). Bioactive and inert dental glass-ceramics. Journal of Biomedical Materials Research Part A. Vol.105, issue (2), pp.: 619-639.
Wang Z., Jiang T., Sauro S., Wangb Y., Thompson I., Watson T. F., Sa Y., Xing W., Shen Y., Haapasalo M. (2011). Dentine remineralization induced by two bioactive glasses developed for air abrasion purposes. Journal of dentistry. Vol.39, pp.:746-756.
Bm, S., P. P. and N. N. Sanghani (2014). Chair Side Application of NovaMin for the Treatment of Dentinal Hypersensitivity- A Novel Technique. Journal of Clinical and Diagnostic Research. Vol.8, issue (10), pp.: 5-8.
Sayed M. E., Dewan H., Alomer N., Alsubaie S., Chohan H. (2021). Efficacy of Desensitizers in Reducing Post-preparation Sensitivity Prior to a Fixed Dental Prosthesis: A Randomized Controlled Clinical Trial. Journal of International Society of Preventive and Community Dentistry. Vol.11, issue (3), pp.:332-339.
Cummins, D. (2010). Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief. The American Journal of Dentistry. Vol.23, PP.: 3-13.
Expert Committee of Dentin Hypersensitivity, S. o. P. D., Chinese Stomatological Association (2019). Guideline for diagnosis, prevention and treatment of dentin hypersensitivity. Zhonghua Kou Qiang Yi Xue Za Zhi. Vol.54, issue (4), pp.: 223-227.
Torres, C. R. G., Silva, T. M., Fonseca, B. M., Sales, A. L. L. S., Holleben, P., Di Nicolo, R., & Borges, A. B. (2014). The effect of three desensitizing agents on dentin hypersensitivity: a randomized, split-mouth clinical trial. Operative dentistry. Vol. 39, issue (5), pp.: 186-194.
Sauro S., Gandolfi M.G., Prati C., Mongiorgi R., Pashley D.H., (2010) Effect of a bioactive glass toothpaste on dentin hypersensitivity: A 6-month clinical trial. Journal of Dentistry. Vol.38, issue (9), pp.: 723-728.
Bühler, J., M. Amato, R. Weiger and C. Walter. (2016). A systematic review on the effects of air polishing devices on oral tissues. International Journal of Dental Hygiene. Vol. 14, Issue (1), pp.: 15-28.
Sauro, S., I. Thompson and T. F. Watson. (2011). Effects of common dental materials used in preventive or operative dentistry on dentin permeability and remineralization. Operative Dentistry. Vol. 36, issue (2), pp.: 222-230.
Yoshiyama M., Tay F.R., Pashley D.H. (2003). Effect of a light-cured desensitizer on dentin adhesion. Journal of Adhesive Dentistry. Vol. 5, issue (2), pp.:107-113.
Holland, G. R., M. N. Narhi, M. Addy, L. Gangarosa and R. Orchardson. (1997). Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Journal of Clinical Periodontology. Vol. 24, issue (11), pp.: 808-813.
Fiocchi, M. F., A. J. Moretti, J. M. Powers and T. Rives. (2007). Treatment of root sensitivity after periodontal therapy. American journal of dentistry. Vol. 20, issue (4), pp.: 217-220.
da Rosa, W. L., R. G. Lund, E. Piva and A. F. da Silva. (2013).The effectiveness of current dentin desensitizing agents used to treat dental hypersensitivity: a systematic review. Quintessence International. Vol. 44, issue (7), pp.: 535-546.
Madruga, M. M., A. F. Silva, W. L. Rosa, E. Piva and R. G. Lund. (2017). Evaluation of dentin hypersensitivity treatment with glass ionomer cements: A randomized clinical trial. Brazilian Oral Research. Vol. 31: e3.
Taha, A. A., M. P. Patel, R. G. Hill and P. S. Fleming. (2017).The effect of bioactive glasses on enamel remineralization: A systematic review. Journal of Dentistry. Vol. 67, pp.: 9-17.
Collaert, B. and C. Fischer. (1991). Dentine hypersensitivity: a review. Dental Traumatology. Vol. 7, issue (4), pp.: 145-152.
Gaffar, A. (1998). Treating hypersensitivity with fluoride varnishes. Compendium of Continuing Education in Dentistry. Vol. 19, issue (11), pp.: 1088-1090, 1092, 1094 passim.
Ritter, A. V., W. L. de Dias, P. Miguez, D. J. Caplan and E. J. Swift Jr. (2006). Treating cervical dentin hypersensitivity with fluoride varnish. The Journal of the American Dental Association. Vol. 137, issue (7), pp.: 1013-1020.
Cummins, D. (2010). Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief. The American Journal of Dentistry. Vol.23, PP.: 3-13.
Abdelwahed, A. G., M. M. Temirek and F. M. Hassan (2019). Antierosive Effect of Topical Fluorides: A Systematic Review and Meta-Analysis of. Open Access Macedonian Journal of Medical Science. Vol. 7, issue (9), pp.: 1523-1530.
Favaro Zeola, L., P. V. Soares and J. Cunha-Cruz. (2019). Prevalence of dentin hypersensitivity: Systematic review and meta-analysis. Journal of Dentistry. Vol. 81, pp.: 1-6.
Sivaramakrishnan, G. and K. Sridharan. (2019). Fluoride varnish versus glutaraldehyde for hypersensitive teeth: a randomized controlled trial, meta-analysis and trial sequential analysis. Clinical oral investigations. Vol. 23, issue (1), pp.: 209-220.
Jalaluddin, M., and Almalki, S. A. (2019). Evaluation of the Efficacy of Three Different Treatment Modalities in the Management of Dentinal Hypersensitivity: A Comparative Study. World. Vol. 10, issue (3), pp.:203.
NOMURA, Y., YASUO, K., IWATA, N., YOSHIKAWA, K.,and YAMAMOTO, K. (2013). Effect of various materials on dentin permeability for the treatment of dentin hypersensitivity. The Japanese Journal of Conservative Dentistry. Vol. 56, issue (6), pp.: 516-525.
Bharath Chandra NR, Kunal Kumar Ghosh, Narayan N Valavalkar, Shobha Prakash. (2016). Evaluation of efficacy of Shied force plus and gluma desensitizer on dentinal tubule occlusion: A scanning electron microscopic study. International Journal of Dental and Health Sciences. Vol.3, issue (1), pp.: 95-104.
Gazhva, S. I., Shurova, N. N., Shkarednaya, O. V., Volkomorova, T. V., and Senina-Volzhskaya, I. V. (2018). Experimental and clinical rationale for the use of modern methods of teeth hyperesthesia treatment. Stomatologiia, Conservative dentistry. Vol. 97, issue (5), pp.:11-18.
Gazhva, S. I., Shurova, N. N., Shkarednaya, O. V., Volkomorova, T. V., andSenina-Volzhskaya, I. V. (2018). Experimental and clinical rationale for the use of modern methods of teeth hyperesthesia treatment. Stomatologiia, Conservative dentistry. Vol. 97, issue (5), pp.: 11-18.
Ashari, M. A., Berijani, A., Anbari, F., Yazdani, Z., and Zandian, A. (2021). Comparison of the Effectiveness of Combined Diode Laser and GLUMA Bonding Therapy with Combined Diode Laser and 5% Sodium Fluoride Varnish in Patients with Dentin Hypersensitivity. Journal of Lasers in Medical Sciences. Vol. 12, pp.: 62-63.
Andersson, O. H. and I. Kangasniemi. (1991). Calcium phosphate formation at the surface of bioactive glass in vitro. Journal of Biomedical Material Research. Vol. 25, issue (8), pp.: 1019-1030.
Ma, Q., T. Wang, Q. Meng, X. Xu, H. Wu, D. Xu and Y. Chen. (2017). Comparison of in vitro dentinal tubule occluding efficacy of two different methods using a nano-scaled bioactive glass-containing desensitising agent. Journal of Dentistry. Vol. 60, pp.: 63-69.
Baglar, S., U. Erdem, M. Dogan and M. Turkoz. (2018). Dentinal tubule occluding capability of nano-hydroxyapatite; The in-vitro evaluation. Microscopic Research Technology. Vol. 81, issue (8), pp.banerjee: 843-854.
Graumann, S. J., M. L. Sensat and J. L. Stoltenberg. (2013). Air polishing: a review of current literature. Journal of Dental Hygiene. Vol. 87, issue (4), pp.: 173-180.
Banerjee, A., M. Hajatdoost-Sani, S. Farrell and I. Thompson. (2010). A clinical evaluation and comparison of bioactive glass and sodium bicarbonate air-polishing powders. Journal od Dentistry. Vol. 38, issue (6), pp.: 475-479.
Sauro, S., T. F. Watson and I. Thompson. (2010). Dentine desensitization induced by prophylactic and air-polishing procedures: an in vitro dentine permeability and confocal microscopy study. Journal of Dentistry. Vol. 38, issue (5), pp.: 411-422.
Charak R, Armour C, Elklit A, Angmo D, Elhai JD, Koot HM. Factor structure of PTSD, and relation with gender in trauma survivors from India. Eur J Psychotraumatol. 2014;5:25547.
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