4-Amino pyrimidine derivatives: design, synthesis, antiviral, and antibacterial investigation

Authors

  • Moktar M. Aburzeza
  • Ismail M. Awheda
  • Wesam A. Kollab
  • Alkhansa O. Abdulnnour

Keywords:

pyrimidine, P2X3 receptor, antiviral, antimicrobial

Abstract

Numerous novel 4-Amino-pyrimidine-5-carbonitrile, 1,3-thiazine, and 1,3,4-thiadiazole derivatives were produced using 2-pyridin-4-ylmethylene) hydrazine-1-carboximidamide as the main starting material. In vitro tests were used to evaluate antiviral and antibacterial qualities. The synthesised compounds were characterised by elemental analysis, FT-IR, 1H NMR, and LC-MS spectral investigations.

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Published

2025-05-22

How to Cite

1.
M. Aburzeza M, M. Awheda I, A. Kollab W, O. Abdulnnour A. 4-Amino pyrimidine derivatives: design, synthesis, antiviral, and antibacterial investigation. J Neonatal Surg [Internet]. 2025May22 [cited 2025Oct.1];14(26S):521-7. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6321