Nanobots in Pharmacy: A Futuristic Approach to Drug Delivery and Therapeutics
DOI:
https://doi.org/10.63682/jns.v14i27S.6429Keywords:
Nanobots, drug delivery, nanotechnology, therapeutics, pharmacy, targeted therapy, biomedical nanorobotics, personalized medicine, futuristic healthcare, nanoengineeringAbstract
Nanotechnology has played a significant role in the modern healthcare and medicine system, particularly through the development of nanobots, which have revolutionized the field of pharmaceutical drug delivery and cancer therapy. Nanobots are tiny robotic devices that, when implanted in the human body, move within biological systems to cancer cells and release therapeutic drugs with the highest accuracy. These devices allow the most targeted therapy approach, limiting the effect of drugs to healthy tissues, reducing systemic side effects, and enhancing treatment output. Furthermore, nanobots can be used to design a real-time monitoring system, early detection, and drug release, which are effective for cancer therapy. This review paper shows the design and implementation potential of such nanobot devices, highlighting their mechanisms, advancements and future prospects
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Z. M. Mazayen, A. M. Ghoneim, R. S. Elbatanony, E. B. Basalious, and E. R. Bendas, “Pharmaceutical nanotechnology: from the bench to the market,” Futur. J. Pharm. Sci., vol. 8, no. 1, p. 12, 2022, doi: 10.1186/s43094-022-00400-0.
D. S. Gupta, D. A. Tomar, D. L. Manohar, and D. P. Panwar, “Nanobots: The current scenario,” Crit. Rev. Oncol. Hematol., vol. 208, p. 104652, 2025, doi: https://doi.org/10.1016/j.critrevonc.2025.104652.
R. Tadikonda and A. Aditya, “Nanobots: The future of drug delivery,” Ars Pharm., vol. 65, pp. 392–408, 2024, doi: 10.30827/ars.v65i4.31068.
A. Javaid, “Medical Nanorobots: Our New Healthcare Defense,” Acad. Lett., no. July 2021, pp. 1–5, 2021, doi: 10.20935/al1629.
M. Mehta and K. Subramani, Nanodiagnostics in Microbiology and Dentistry, First Edit. Elsevier Inc., 2011. doi: 10.1016/B978-1-4557-7862-1.00021-3.
A. Gupta, S. Soni, N. Chauhan, M. Khanuja, and U. Jain, “Nanobots-based advancement in targeted drug delivery and imaging: An update,” J. Control. Release, vol. 349, pp. 97–108, 2022, doi: https://doi.org/10.1016/j.jconrel.2022.06.020.
M. Biswas, “AI-Powered nanorobots: A mini review on innovations in healthcare,” J. Artif. Intell. Robot., vol. 1, no. 2, pp. 1–4, 2024, doi: 10.61577/jaiar.2024.100007.
X. Kong, P. Gao, J. Wang, Y. Fang, and K. C. Hwang, “Advances of medical nanorobots for future cancer treatments,” J. Hematol. Oncol., vol. 16, no. 1, pp. 1–45, 2023, doi: 10.1186/s13045-023-01463-z.
D. Dutta and S. K. Sailapu, “Chapter 10 - Biomedical Applications of Nanobots,” in Intelligent Nanomaterials for Drug Delivery Applications, N. Ahmad and P. Gopinath, Eds., Elsevier, 2020, pp. 179–195. doi: https://doi.org/10.1016/B978-0-12-817830-0.00010-2.
R. Tripathi and A. Kumar, “Application of Nanorobotics for Cancer Treatment,” Mater. Today Proc., vol. 5, no. 3, Part 1, pp. 9114–9117, 2018, doi: https://doi.org/10.1016/j.matpr.2017.10.029.
M. Hu, X. Ge, X. Chen, W. Mao, X. Qian, and W.-E. Yuan, “Micro/Nanorobot: A Promising Targeted Drug Delivery System.,” Pharmaceutics, vol. 12, no. 7, Jul. 2020, doi: 10.3390/pharmaceutics12070665.
C. Simó et al., “Urease-powered nanobots for radionuclide bladder cancer therapy,” Nat. Nanotechnol., vol. 19, no. 4, pp. 554–564, 2024, doi: 10.1038/s41565-023-01577-y.
K. Sharma and R. Ranjan, “Intelligent Nanorobots for Precision Cancer Diagnosis and Treatment using Deep Reinforcement Learning,” in 2025 11th International Conference on Mechatronics and Robotics Engineering (ICMRE), 2025, pp. 90–94. doi: 10.1109/ICMRE64970.2025.10976292.
R. Devasena Umai, P. Brindha Devi, and R. Thiruchelvi, “A review on dna nanobots – A new technique for cancer treatment,” Asian J. Pharm. Clin. Res., vol. 11, no. 6, pp. 61–64, 2018, doi: 10.22159/ajpcr.2018.v11i6.25015.
M. Aggarwal and S. Kumar, “The Use of Nanorobotics in the Treatment Therapy of Cancer and Its Future Aspects: A Review,” Cureus, vol. 14, no. 9, 2022, doi: 10.7759/cureus.29366.
F. Soto and R. Chrostowski, “Frontiers of medical micro/nanorobotics: In vivo applications and commercialization perspectives toward clinical uses,” Front. Bioeng. Biotechnol., vol. 6, no. NOV, pp. 1–12, 2018, doi: 10.3389/fbioe.2018.00170.
S. Li et al., “A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo,” Nat. Biotechnol., vol. 36, no. 3, pp. 258–264, 2018, doi: 10.1038/nbt.4071.
S. Andhari, G. Khutale, R. Gupta, Y. Patil, and J. Khandare, “Chemical tunability of advanced materials used in the fabrication of micro/nanobots,” J. Mater. Chem. B, vol. 11, no. 24, pp. 5301–5320, 2023, doi: 10.1039/d2tb02743g.
S. M. R. Seyedi, A. Asoodeh, and M. Darroudi, “The human immune cell simulated anti-breast cancer nanorobot: the efficient, traceable, and dirigible anticancer bio-bot,” Cancer Nanotechnol., vol. 13, no. 1, pp. 1–24, 2022, doi: 10.1186/s12645-022-00150-x.
S. S. Andhari et al., “Self-Propelling Targeted Magneto-Nanobots for Deep Tumor Penetration and pH-Responsive Intracellular Drug Delivery,” Sci. Rep., vol. 10, no. 1, p. 4703, 2020, doi: 10.1038/s41598-020-61586-y.
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