Maternal Periodontitis and Neonatal Inflammation: A Prospective Cohort Study

Authors

  • S. Parthiban
  • B.Roshan Arbaaz
  • Snophia suresh
  • Khumukcham Sophia
  • kadhiresan. R
  • A.Nihal Ahamed

Keywords:

Periodontitis, neonatal inflammation, pregnancy outcomes, prenatal care

Abstract

Background: Periodontitis has been linked to adverse pregnancy outcomes , but its impact on neonatal inflammation remains unclear.

Objective: To investigate the relationship between maternal periodontitis and neonatal inflammation .

Methods: A prospective cohort study was conducted among pregnant women with periodontitis and healthy controls. Maternal periodontal status was assessed, and neonatal cord blood was analyzed for inflammatory markers (IL-6 and TNF-α).

Results: Maternal periodontitis was associated with increased neonatal inflammatory markers (IL-6 and TNF-α) and lower birth weight. A positive correlation was found between maternal periodontal disease severity and neonatal inflammatory markers.

Conclusion: Maternal periodontitis is associated with increased neonatal inflammation , suggesting a potential link between maternal oral health and fetal development. These findings highlight the importance of prenatal periodontal care in reducing adverse birth outcomes.

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References

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Published

2025-05-27

How to Cite

1.
Parthiban S, Arbaaz B, suresh S, Sophia K, R kadhiresan., Ahamed A. Maternal Periodontitis and Neonatal Inflammation: A Prospective Cohort Study. J Neonatal Surg [Internet]. 2025May27 [cited 2025Sep.13];14(28S):462-6. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6632

Issue

Vol. 14 No. 28S (2025): Journal of Neonatal Surgery

Section

Original Article

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