A Clinical Study Of Maternal And Fetal Outcome In Cases Of Abruptio Placentae

Authors

  • Stuti Shah
  • Priyal Macwan
  • Anamika Dhanger
  • Aayush Patel
  • Manali Kagathara

Keywords:

abruptio placentae, placental abruption, maternal outcome, perinatal outcome, Page classification, India

Abstract

Background Placental abruption (abruptio placentae) is a life-threatening obstetric emergency contributing substantially to global maternal morbidity/mortality and perinatal loss. The burden in low- and middle-income settings remains under-reported.
Methods We performed a prospective observational study in the Department of Obstetrics and Gynaecology, GMERS Medical College, Gandhinagar (November 2022 – April 2024). All singleton pregnancies ≥ 28 weeks with clinically or ultrasonographically confirmed abruption were enrolled (n = 109). Maternal socio-demographic details, etiological factors, Page’s grade, interventions, and fetomaternal outcomes were recorded. Data were analysed with Epi-Info 7; results are expressed as mean ± SD, proportions, and case-fatality rate.

Results Incidence was 1.26 % (109/8 613 deliveries). Mean maternal age was 27.1 ± 4.5 years; 86 % resided in rural areas and 80 % were unbooked. Grade 2 abruption predominated (51.4 %). Pre-eclampsia spectrum (40.2 %), anaemia (70.6 %), and multiparity were major risk factors. Vaginal delivery occurred in 54 %, caesarean section in 46 %. Maternal complications included postpartum haemorrhage (26.6 %), shock (11 %), acute renal failure (9.2 %) and DIC (3.7 %). Maternal case-fatality rate was 1.96 %. Mean birth-weight was 1.87 ± 0.62 kg; 65 % of neonates had 1-min Apgar < 7 and 43 % required NICU admission. Overall intra-uterine death plus stillbirth rate was 43.2 %, and perinatal mortality 19.3 %.

Conclusion Abruptio placentae remains a formidable contributor to adverse fetomaternal outcomes. Early detection of hypertensive disorders, timely referral, and preparedness for massive transfusion can mitigate morbidity. Strengthening antenatal coverage in rural populations is paramount.

Downloads

Download data is not yet available.

References

Ananth CV, Wilcox AJ. Placental abruption and perinatal mortality in the United States. JAMA. 2001;285:1899-1903.

Tikkanen M. Placental abruption: epidemiology, risk factors and consequences. Acta Obstet Gynecol Scand. 2011;90:140-149.

Oyelese Y, Ananth CV. Placental abruption. Obstet Gynecol. 2006;108:1005-1016.

Hossain N, Khan N, Sultana SS, Khan N. Abruptio placentae and adverse pregnancy outcome. J Pak Med Assoc. 2010;60:443-446.

Sahu L et al. Abruptio placentae: risk factors and maternal outcome-–A rural Indian study. J Obstet Gynecol India. 2016;66:239-244.

Chen Y, et al. Independent risk factors for placental abruption: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2025;25:74.

Brown R, Isaacs W. Page classification revisited: clinical utility in modern obstetric care. Int J Obstet Anesth. 2022;50:103583.

United Nations. Sustainable Development Goals Report 2024.

Patil A, et al. Clinical study of abruptio placentae and fetomaternal outcome in a tertiary care hospital. Trans Clin Med Sci. 2023;3:S14-S20.

Kapadia LD, Dhrangiya B. Maternal and perinatal outcome in 100 cases of abruptio placentae. Int J Med Res Health Sci. 2017;6:84-88.

Rosenberg A, et al. Diagnostic accuracy of ultrasound in placental abruption. Ultrasound Obstet Gynecol. 2019;53:226-232.

Basnet P, et al. Fetomaternal outcome of antepartum haemorrhage in Nepal. BMC Pregnancy Childbirth. 2021;21:459.

Verma R, et al. Abruptio placentae: a retrospective analysis of 500 cases. J Obstet Gynecol India. 2003;53:546-549.

Salihu HM, et al. Extreme low birth weight and placental abruption. Early Hum Dev. 2018;120:62-67.

Mosborg-Peterson A et al. Circulating cfDNA as predictor of placental abruption. Prenat Diagn. 2024;44:987-994.

Downloads

Published

2025-05-30

How to Cite

1.
Shah S, Macwan P, Dhanger A, Patel A, Kagathara M. A Clinical Study Of Maternal And Fetal Outcome In Cases Of Abruptio Placentae. J Neonatal Surg [Internet]. 2025May30 [cited 2025Oct.29];14(29S):324-8. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6792