Study Of Tableting Properties of C12, C14, C16, C18 Saturated Fatty Acid Derivatives of Starch Soluble

Authors

  • Naveen Khatri
  • Sandeep Jain
  • Neelam Jain

Keywords:

N\A

Abstract

Pharmaceutical excipients are needed in a formulation as diluents, binders, and other constituents. One of the most employed excipients in the pharmaceutical industry is starch, which has both the binding and disintegrating capabilities. This study assesses starch long-chain saturated fatty acid derivatives (C12- C18) for their weight, physical, excipient, and tableting features. The results argume that fat acid esterification results in hydrophobicity which facilitates sustained the drug release. Starch laurate (C12) demonstrated (23.6 cps) and (angle of repose: 30.73°) the greatest viscostiy and flowability, respectively; while starch stearate (C18) had the slowest drug release rate. These suggest to the premise that modified starches with fatty acids are good candidate excipients for sustained release formulation.

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Published

2025-05-31

How to Cite

1.
Khatri N, Jain S, Jain N. Study Of Tableting Properties of C12, C14, C16, C18 Saturated Fatty Acid Derivatives of Starch Soluble. J Neonatal Surg [Internet]. 2025May31 [cited 2025Sep.21];14(26S):952-60. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6868

Issue

Vol. 14 No. 26S (2025): Journal of Neonatal Surgery

Section

Original Article

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