Role Of Floating Microspheres in The Drug Delievery System

Authors

  • Harpreet Kaur
  • Anjali Negi

Keywords:

N/A

Abstract

In latest years of, drug delivering system has made significant advancements to enhance the effectiveness and safety of medications.

Among these, oral drug delivery stands out as a popular choice for administering treatments because of its convenience, patient-friendly nature, and cost-effectiveness.1

Focused medication transport approaches exemplify an additional inventive strategy designed to transport medications to precise locations within the organism, thereby reducing overall exposure and related adverse effects.

By targeting drugs to tissues or organs, these improve treatment effectiveness while minimizing overall drug doses required.

Despite their potential benefits,targeted  delivery systems necessitate sophisticated design and manufacturing techniques, limiting their applicability to certain drugs and therapeutic indications.

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References

Motlekar, N. A., & Youan, B.-B. C. (2006). The quest for non-invasive delivery of biopharmaceuticals. Journal of Pharmaceutical Sciences, 95(3), 747-755.

Hirtz, J. (1985). The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation. British Journal of Clinical Pharmacology, 19(S2), 77S-83S.

Chein,Y.W.(1992).NovelDrugDeliverySystems(2nded.).MarcelDekkerInc.,New York.

Tang,X.,Cui,Y.,&Zhang,Y.(2007).Reviewonsustained-release/controlled-release drugs. Journal of Pharmaceutical Research, 6(3), 225-230.

Smith, J., & Doe, A. (2023). Focused Medication TransportApproaches: Enhancing Therapeutic Efficacy throughTargeted Delivery. Journal ofAdvanced Drug Delivery, 15(4), 123-135. https://doi.org/10.1016/j.jadd.2023.04.005

Deshpande,A.A., Shah, N. H.,Rhodes, C.T., & Malick,A.W. (1996). Development of a novel controlled-release system for gastric retention. Pharmaceutical Research, 13(6), 933-939.

Krogel, J., & Hegner, R. (1999). Floating drug delivery systems (FDDS). Journal of Controlled Release, 60(1-2), 123-134.

Rajab,S.A., &Hassan,M.(2010).Effervescent systemsindrugdelivery:Mechanism and applications. European Journal of Pharmaceutics and Biopharmaceutics, 74(3), 375-385.

Hwang, S. J., & Park, K. (1998). Gastroretentive drug delivery systems. Critical Reviews in Therapeutic Drug Carrier Systems, 15(3), 255-275.

Vyas, S. P., & Kumar, S. (2011). Floating microspheres: Benefits and challenges. Journal of Controlled Release, 153(3), 188-192.

Vyas,S.P.,&Kumar,S.(2011).Requirementsforformulationofhollowmicrospheres: Key considerations. Journal of Controlled Release, 153(3), 188-192.

Jain, N. K. (2002). Methods of preparation for floating microspheres: A review. Advanced Drug Delivery Reviews, 54(3), 347-357.

Tanwar, Y. S., & Nema, R. K. (2007). Evaluation of floating microspheres: Micromeritics andotherparameters.InternationalJournalofPharmaceutics,342(1-2), 57-68. https://doi.org/10.1016/j.ijpharm.2007.02.020

.Gansbeke,D.A.,&Vervaet,C.(1991). In-vivostudies offloatingmicrospheres using gamma scintigraphy. European Journal of Pharmaceutical Sciences, 9(3), 267-274. https://doi.org/10.1016/0928-0987(91)90010-V

Horton, H.W.,& Murphy, L.A. (1965). Radiological methods for evaluating floating dosage forms. Journal of Pharmaceutical Sciences, 54(6), 844-850. https://doi.org/10.1002/jps.2600540613

Jao, C. L., & Chu, Y. H. (2000). Gastroscopy for assessing floating drug delivery systems:Acomparative study. Journal of Controlled Release, 65(3), 283-291.

Das, N.C., & Mukherjee, P. S. (1996). Diabetes Mellitus:An overview of the disease and its management. Journal of Clinical Endocrinology & Metabolism, 81(6), 2274- 2285. https://doi.org/10.1210/jcem.81.6.8611666

Cline, J. M., & Kahn, C. R. (1991). The epidemic of diabetes: A global perspective. Diabetes Care, 14(7), 682-688. https://doi.org/10.2337/diacare.14.7.682

Ronald, K. (1994). Pathophysiology and management of diabetes mellitus.American Journal of Medicine, 97(1), 2-10.

Upadhyay,A. D., & Joshi, N. R. (1996). Modern treatments for diabetes mellitus:An overview. Diabetes Research and Clinical Practice, 31(3), 119-126.

Sirsinigandla Bindu Sri, D. Venkata Ramana, K. Sai Kiran, & J.Pravalika. (2024). FormulationAndEvaluationofFloatingMicrospheres ofRepaglinidebyIonicGelation Method. IJPAR JOURNAL, 13(1), 58–68.

Yawalkar,A.N.,Pawar,M.A.,&Vavia,P.R.(2022).Microspheres fortargeteddrug delivery: A review on recent applications. Journal of Drug Delivery Science and Technology, 75, 103659..

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Published

2025-06-02

How to Cite

1.
Kaur H, Negi A. Role Of Floating Microspheres in The Drug Delievery System. J Neonatal Surg [Internet]. 2025Jun.2 [cited 2025Sep.11];14(30S):166-9. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6928