Phytochemical and Biological investigations of the active constituents of various parts of Solanum indicum
Keywords:
Solanum indicum, pharmacolgocial activity, Phytochmcial screeningAbstract
Solanum indicum, commonly known as Indian nightshade, has demonstrated diverse pharmacological activities across its various extracts. Studies have shown that leaf extracts possess significant antioxidant properties, potentially due to the presence of phenolic compounds and flavonoids. The fruit extracts have exhibited notable antimicrobial effects against several pathogenic bacteria and fungi, suggesting their potential use in treating infectious diseases. Additionally, root extracts have displayed anti-inflammatory and analgesic activities in animal models, indicating possible applications in pain management. Some research has also highlighted the potential antidiabetic properties of S. indicum extracts, with observed reductions in blood glucose levels in experimental studies. Furthermore, preliminary investigations have suggested antitumor activities in certain extracts, though more comprehensive research is needed to fully elucidate these effects and their underlying mechanisms. To guarantee quality, efficacy, and repeatability, this study focused on standardising and testing Solanum indicum extracts and isolated components. Flavonoids, phenolic acids, alkaloids, and terpenoids are examples of moderately polar compounds that can be extracted using C6H14. The extracts, particularly the C2H5OH and CH3COOC2H5 extracts, exhibited significant antibacterial, antioxidant properties and Anthelmintic properties.
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