Phytochemical And Pharmacological Evaluation Of Aqueous Polyherbal Extract Against Pheretima Posthuma
Abstract
The present study was to evaluate the phytochemical screening and antihelmintic activity of aqueous polyherbal extract (APHE) against Pheretima posthuma. The raw materials of Asparagus racemosus, Foeniculum vulgare, Cymbopogon citratus, Curcuma longa, Moringa oleifera were identified and purchased from local market of Nuzvid. APHE was prepared from the dried materials of five different plants using the solvent water. Initially, APHE was screened for phytochemical constituents by standard methods. Further, antihelmintic study was conducted against Pheretima posthuma, collected from local Vermicomposting Farm, Nuzvid. In the phytochemical screening, APHE showed presence of glycosides, alkaloids, flavonoids, phenols, phytosterols and tannins. In the antihelmintic study, mortality was produced in earth worm populations by APHE. The use of APHE as an antihelmintic was confirmed by using standard method against Pheretima posthuma. The results indicated that the test drug has significant antihelmintic properties. The data were found statistically significant by using one way ANOVA (P< 0.0001). Hence, it can be concluded that the APHE can be used as a novel drug for the treatment of worm infestations.
Downloads
References
Das, et al., Determination of Anthelmintic Activity of the Leaf and Bark Extract of Tamarindus Indica Linn, Indian Journal of Pharmaceutical Sciences, 73 (1), 2011, 104-107.
Taepongsorat and Rattana, Antioxidant Activities of Ethanolic and Aqueous Extracts of Asparagus racemosus Roots, Pharmacognosy Journal, 10(6), 2018, 1129-32.
Hakim Md. Osman Gani, Dr. Md. Obydul Hoq and Tahmina Tamanna, Pharmacological and phytochemical analysis of Foeniculum vulgare Mill: A review, International Journal of Unani and Integrative Medicine 2019; 3(2): 13-18.
A. Tazi, A. Zinedine, J.M. Rocha et al. Review on the pharmacological properties of lemongrass (Cymbopogon citratus) as a promising source of bioactive compounds, Pharmacological Research - Natural Products 3 (2024) 100046.
E.J. Iweala, M.E. Uche, E.D. Dike et al., Curcuma longa (Turmeric): Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicity profiles —A review, Pharmacological Research - Modern Chinese Medicine 6 (2023) 100222.
Ariani L.N., Estiasih T., Sunarharum W.B., Khatib A. (2023): Potential of Moringa (Moringa oleifera) leaf powder for functional food ingredients: A review. Czech Journal of Food Science.1-13.
Manohar et.al, Phytochemical Analysis of Ethanolic Extract of Fruits of Terminalia chebula (EEFTC), Drug Invention Today, 4(10), 2012, 491-492.
Aishwarya, K. Apte., Khot, V. S., Biradar, N.S., and Patil, S. B. (2014). Anthelmintic activity of Trachyspermum Ammi extract. International Journal of Pharmacy and Pharmaceutical Sciences, 6(1), 464-466.
Trupti, P. Durgawale., Chitra, C. Khanwelkar., Pratik, P. Durgawale and Satish V. Kakade. (2017). Comparative Anthelmintic Activity of Different Extracts of Portulaca oleraceae L. Whole Plant. Biomedical & Pharmacology Journal, 10(4), 2013-2016.
Jinu John Archana Mehta Shruti Shukla and Pradeep Mehta. A report on anthelmintic activity of Cassia tora leaves, Songklanakarin Journal of Science and Technology, 31(3), 2009, 269-271.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
