Impact of Community-Level Stigma on Mental Health Outcomes in TB-Affected Individuals
Keywords:
Tuberculosis, Stigma, Mental Health, CommunityAbstract
Objective: To evaluate mental health outcomes among TB affected individuals
Material & Methods: Patients with tuberculosis who visited the TB Health Care Center in Lahore between September 2024 and May 2025 participated in a cross-sectional survey. Ethical approval for this study was obtained from the Ethical Review Committee. All procedures performed were in accordance with institutional guidelines, and informed consent was obtained from all participants prior to data collection. Convenient sampling was used to choose the respondents. Before the survey began, each patient's informed permission was also obtained
Result: 200 patients in all, with a mean age of 45 ± 17.4 years, participated; 77% of them were men and 55% were married. A household income of between 26,000 and 50,000 PKR was earned by almost half, and 56% were enrolled in continuing therapy. 50% reported moderate illness severity, and 35% smoked and had co-morbidities. Anxiety (53%), depression (61.5%), and a lack of social support (44.5%) were prevalent. Gender, education, the severity and length of the condition, and the stage of therapy were all substantially correlated with perceived stigma. The length and severity of the condition, low income, and education were all associated with poor social support. Patients who had been with the condition longer, had less education, and felt stigmatized were more likely to experience depression and anxiety.
Conclusion:The severity and length of the disease, together with social and demographic variables, exacerbate the psychological misery and shame that TB patients frequently endure. To tackle these issues, specific public awareness campaigns and protection from marginalization are necessary. Such initiatives can enhance the quality of life for patients and advance a society that is more inclusive and caring
Downloads
References
Aggarwal AN. Quality of life with tuberculosis. Journal of clinical tuberculosis and other mycobacterial diseases. 2019 Dec 1;17:100121.
Evans L, Chang A, Dehon J, Streb M, Bruce M, Clark E, Handal P. The relationships between perceived mental illness prevalence, mental illness stigma, and attitudes toward help-seeking. Current Psychology. 2024 Jan;43(2):1806-15.
Craig GM, Daftary A, Engel N, O’driscoll S, Ioannaki A. Tuberculosis stigma as a social determinant of health: a systematic mapping review of research in low incidence countries. International Journal of Infectious Diseases. 2017 Mar 1;56:90-100.
Nyblade L, Stockton MA, Giger K, Bond V, Ekstrand ML, Lean RM, Mitchell EM, Nelson LR, Sapag JC, Siraprapasiri T, Turan J. Stigma in health facilities: why it matters and how we can change it. BMC medicine. 2019 Dec;17:1-5.
Bhargava A, Bhargava M, Juneja A. Social determinants of tuberculosis: context, framework, and the way forward to ending TB in India. Expert Review of Respiratory Medicine. 2021 Jul 3;15(7):867-83.
Bresenham D, Kipp AM, Medina-Marino A. Quantification and correlates of tuberculosis stigma along the tuberculosis testing and treatment cascades in South Africa: a cross-sectional study. Infectious Diseases of Poverty. 2020 Dec;9:1-3.
Lolong DB, Aryastami NK, Kusrini I, Tobing KL, Tarigan I, Isfandari S, Senewe FP, Raflizar, Endah N, Sitorus N, Pangaribuan L. Nonadherence to anti-tuberculosis treatment, reasons and associated factors among pulmonary tuberculosis patients in the communities in Indonesia. PLoS One. 2023 Aug 8;18(8):e0287628.
Thomas BE, Stephen A. Tuberculosis related stigma in India: roadblocks and the way forward. Expert Review of Respiratory Medicine. 2021 Jul 3;15(7):859-61.
Zakaria R, Amri NS, Mohamad N. Stigma and depression among tuberculosis patients in Kedah, Malaysia. IIUM Medical Journal Malaysia. 2022 Oct 1;21(4).
Chen X, Chen Y, Zhou L, Tong J. The role of self-esteem as moderator of the relationship between experienced stigma and anxiety and depression among tuberculosis patients. Scientific reports. 2023 Apr 27;13(1):6889.
Akhtar N, Batool I, Khan MZ. Perceived Stigma, Social Support and Quality of Life in Patients of Tuberculosis: Quality of Life in Patients of TB. Pakistan Journal of Health Sciences. 2023 Jan 31:89-93.
Umar M, Basit A, Ali S, Iqbal Z. Understanding the burden: prevalence and predictors of depression and anxiety among multidrug-resistant tuberculosis patients and their household contacts. Pakistan Journal of Chest Medicine. 2022 Mar 2;28(1):72-9.
World Health Organization. WHO Evidence Considerations for Vaccine Policy Development for Tuberculosis Vaccines Intended for Adults and Adolescents. World Health Organization; 2024 May 28.
Shahzad M, Andrews SC, Ul-Haq Z. Exploring the role of Microbiome in Susceptibility, Treatment Response and Outcome among Tuberculosis Patients from Pakistan: study protocol for a prospective cohort study (Micro-STOP). BMJ open. 2022 Jun 1;12(6):e058463.
Mustafa T, Shahzad Y, Kiani A. A survey of knowledge, attitude, and practices of private retail pharmacies staff in tuberculosis care: study from Dera Ismail Khan City, Pakistan. Journal of Pharmaceutical Policy and Practice. 2018 Dec;11:1-7.
Liu K, Zhang Y, Qu S, Yang W, Guo L, Zhang L. Prevalence and correlates of anxiety and depressive symptoms in patients with and without multi-drug resistant pulmonary tuberculosis in China. Frontiers in Psychiatry. 2021 Sep 7;12:674891.
Ali SM, Anjum N, Ishaq M, Naureen F, Noor A, Rashid A, Abbas SM, Viney K. Community knowledge about tuberculosis and perception about tuberculosis-associated stigma in Pakistan. societies. 2019 Jan 23;9(1):9.
Khan A, Shaikh BT, Baig MA. Knowledge, Awareness, and Health‐Seeking Behaviour regarding Tuberculosis in a Rural District of Khyber Pakhtunkhwa, Pakistan. BioMed research international. 2020;2020(1):1850541.
Shamputa IC, Law MA, Kelly C, Nguyen DT, Burdo T, Umar J, Barker K, Webster D. Tuberculosis related barriers and facilitators among immigrants in Atlantic Canada: a qualitative study. PLOS Global Public Health. 2023 Jun 5;3(6):e0001997.
Kocalevent RD, Berg L, Beutel ME, Hinz A, Zenger M, Härter M, Nater U, Brähler E. Social support in the general population: standardization of the Oslo social support scale (OSSS-3). BMC psychology. 2018 Dec;6:1-8.
Kroenke K, Spitzer RL, Williams JB. The PHQ‐9: validity of a brief depression severity measure. Journal of general internal medicine. 2001 Sep;16(9):606-13.
Chen X, Du L, Wu R, Xu J, Ji H, Zhang Y, Zhu X, Zhou L. Tuberculosis-related stigma and its determinants in Dalian, Northeast China: a cross-sectional study. BMC public health. 2021 Dec;21:1-0.
Xu M, Markström U, Lyu J, Xu L. Survey on tuberculosis patients in rural areas in China: tracing the role of stigma in psychological distress. International journal of environmental research and public health. 2017 Oct;14(10):1171.
Teo AK, Tan RK, Smyth C, Soltan V, Eng S, Ork C, Sok N, Tuot S, Hsu LY, Yi S. Characterizing and measuring tuberculosis stigma in the community: a mixed-methods study in Cambodia. InOpen forum infectious diseases 2020 Oct (Vol. 7, No. 10, p. ofaa422). US: Oxford University Press.
Mbuthia GW, Nyamogoba HD, Chiang SS, McGarvey ST. Burden of stigma among tuberculosis patients in a pastoralist community in Kenya: A mixed methods study. PloS one. 2020 Oct 15;15(10):e0240457.
Shah RB, Shah AM, Patel PM, Thakker RM. Stigma associated with tuberculosis–An Indian perspective. National Journal of Physiology, Pharmacy and Pharmacology. 2020;10(7):579-85.
Shivapujimath R, Rao AP, Nilima AR, Shilpa DM. A cross-sectional study to assess the stigma associated with tuberculosis among tuberculosis patients in Udupi district, Karnataka. Indian Journal of Tuberculosis. 2017 Oct 1;64(4):323-6.
Rouf A, Masoodi MA, Dar MM, Khan SM, Bilquise R. Depression among Tuberculosis patients and its association with treatment outcomes in district Srinagar. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 2021 Dec 1;25:100281.
Rizvi N. Frequency of depression and anxiety among tuberculosis patients. Journal of Tuberculosis Research. 2016;4(04):183.
Datiko DG, Jerene D, Suarez P. Stigma matters in ending tuberculosis: Nationwide survey of stigma in Ethiopia. BMC Public Health. 2020 Feb 6;20(1):190.
Duko B, Bedaso A, Ayano G, Yohannis Z. Perceived stigma and associated factors among patient with tuberculosis, Wolaita Sodo, Ethiopia: Cross‐sectional study. Tuberculosis research and treatment. 2019;2019(1):5917537.
Mohammedhussein M, Hajure M, Shifa JE, Hassen TA. Perceived stigma among patient with pulmonary tuberculosis at public health facilities in southwest Ethiopia: A cross-sectional study. PLoS One. 2020 Dec 8;15(12):e0243433.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.