Physiological Responses to Acute Stress: Hormonal and Cardiovascular Changes in Young Adults
DOI:
https://doi.org/10.63682/jns.v14i26S.8539Keywords:
Acute Stress, Cortisol, Blood Pressure, Heart RateAbstract
Background: Under stress, acute stress sets in motion many physiological changes overseen by the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS). Seeing these reactions in younger people helps find early signs of stress-based illnesses.
Objectves: To examine how cortisol and heart rate/blood pressure are affected by stress in healthy young people.
Study Design: A Cross-sectional study.
Place and Duration of study Department of Physiology, Watim Medical & Dental College, Rawat, Pakistan from Jan 2023 to Jan 2024.
Methodology :A cross-sectional study was carried out with 80 students at a university who were 18 to 25 years old. People in the study completed the Trier Social Stress Test (TSST). Blood pressure, heart rate and cortisol in saliva were measured before and after each person underwent a stressful experience.
Results : Increased levels of cortisol were observed after the stressor (on average 7.6 ± 2.3 µg/dL, p < 0.001) compared to pre-stress. Both systolic and diastolic pressure went up by 12% and 9%, respectively and the heart rate increased by 15 beats per minute on average (p < 0.001). Men had a stronger response of the heart; women’s cortisol levels were more variable.
Conclusion: Young adults show major changes in hormonal and cardiovascular systems due to acute stress. This proves why it’s important to address stress early so health issues do not last a long time
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Kirschbaum C, Pirke KM, Hellhammer DH. The 'Trier Social Stress Test'—a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology. 1993;28(1-2):76-81.
Hellhammer DH, Wüst S, Kudielka BM. Salivary cortisol as a biomarker in stress research. Psychoneuroendocrinology. 2009;34(2):163-171.
McEwen BS. Protective and damaging effects of stress mediators: central role of the brain. Dialogues Clin Neurosci. 2006;8(4):367-381.
Chrousos GP. Stress and disorders of the stress system. Nat Rev Endocrinol. 2009;5(7):374-381.
Pruessner JC, Hellhammer DH, Kirschbaum C. Burnout, perceived stress, and cortisol responses to awakening. Psychosom Med. 1999;61(2):197-204.
Kudielka BM, Kirschbaum C. Sex differences in HPA axis responses to stress: a review. Biol Psychol. 2005;69(1):113-132.
al'Absi M, Bongard S, Lovallo WR. Adrenocortical responses to public speaking, mental arithmetic, and cold pressor challenges. Psychosom Med. 1997;59(4):447-456.
Brosschot JF, Gerin W, Thayer JF. The perseverative cognition hypothesis: a review of worry, prolonged stress-related physiological activation, and health. J Psychosom Res. 2006;60(2):113-124.
Pruessner JC, Baldwin MW, Dedovic K, Renwick R, Mahani NK, Lord C, Meaney MJ, Lupien SJ. Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood. Neuroimage. 2005;28(4):815-826.
Kirschbaum C, Kudielka BM, Gaab J, Schommer NC, Hellhammer DH. Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosom Med. 1999;61(2):154-162.
Kudielka BM, Hellhammer DH, Kirschbaum C. Ten years of research with the Trier Social Stress Test—revisited. In: Harmon-Jones E, Winkielman P, editors. Social Neuroscience: Integrating Biological and Psychological Explanations of Social Behavior. New York: Guilford Press; 2007. p. 56-83.Wikipedia+1ResearchGate+1
Kudielka BM, Buske-Kirschbaum A, Hellhammer DH, Kirschbaum C. HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender. Psychoneuroendocrinology. 2004;29(1):83-98.
Kudielka BM, Hellhammer DH, Kirschbaum C. Sex differences in HPA axis responses to stress: a review. Biol Psychol. 2007;74(1):16-28.
al'Absi M, Wittmers LE. Enhanced adrenocortical responses to stress in abstinent smokers. Psychosom Med. 2003;65(2):246-251.
Brosschot JF, Pieper S, Thayer JF. Expanding stress theory: prolonged activation and perseverative cognition. Psychoneuroendocrinology. 2005;30(10):1043-1049.
Pruessner JC, Dedovic K, Khalili-Mahani N, Engert V, Pruessner M, Buss C, Renwick R, Dagher A, Meaney MJ, Lupien S. Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry. 2008;63(2):234-240.
Kirschbaum C, Hellhammer DH. Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology. 1994;19(4):313-333.
Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S, Kaspers F, Kirschbaum C. Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. Life Sci. 1997;61(26):2539-2549.
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