Assessment Of Quality Of Life Amongst Oral Cancer Patients: A Prospective Questionnaire Based Study
Keywords:
chemoradiotherapy, mastication, oral cancer, saliva, swallowing, quality of lifeAbstract
Introduction: Oral cancers are one of the most prevalent cancers worldwide, with significant health implications. The management of oral cancer often involves a combination of surgery, radiotherapy, and chemoradiotherapy, which while life-saving can lead to profound consequences on patient’s physical, psychological & social wellbeing.
Aim: To Evaluate QOL in oral cancer patients & assess the variables predicting the difficulty in mastication, swallowing and salivation after treatment, like surgical resection and chemoradiotherapy.
Method: A total of 82 patients were recorded qualifying the inclusion criteria of Biopsy proven Oral squamous cell carcinoma, Clinical TNM stage III & IV, No evidence of distant metastasis, No history of recurrence of cancer, and who would be Reconstructed at the time of surgical resection with distant flap. set of questionnaire comprises of data regarding quality of life
Results: The progression of patients' quality of life (QOL) was evaluated across three visits during the treatment period, revealing significant improvements over time. At the initial assessment, none of the patients reported a "Good" QOL. The majority were categorized as having a "Satisfactory" QOL. Notably, the "Satisfactory" and "Poor" QOL categories were entirely eliminated, indicating a universal enhancement in patients' well-being.
Conclusion: Quality of life is a concept that has become increasingly important in relation to patient outcomes following treatment for cancer.. The present analysis of patient-reported QOL outcomes may help guide treatment decisions for patients with OSCC based on accurate expectations of adverse effects of cancer treatment..
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Nemeth D, Zaleczna L, Huremovic A, Engelmann J, Poeschl PW, Strasz M, Holawe S, Kornek G, Laskus A, Sacher C, Erovic BM. Importance of chewing, saliva, and swallowing function in patients with advanced oral cancer undergoing preoperative chemoradiotherapy: a prospective study of quality of life. International journal of oral and maxillofacial surgery. 2017 Oct 1;46(10):1229-36.
Hatta JM, Doss JG, Rogers SN. The feasibility of using Patients Concerns Inventory (PCI) in managing Malaysian oral cancer patients. International Journal of Oral and Maxillofacial Surgery. 2014 Feb 1;43(2):147-55.
Becker ST, Menzebach M, Küchler T, Hertrampf K, Wenz HJ, Wiltfang J. Quality of life in oral cancer patients–effects of mandible resection and socio-cultural aspects. Journal of Cranio-Maxillofacial Surgery. 2012
Chandu A, Sun KC, DeSilva RN, Smith AC. The assessment of quality of life in patients who have undergone surgery for oral cancer: a preliminary report. Journal of oral and maxillofacial surgery. 2005 Nov 1;63(11):1606-12.
Pandey M, Devi N, Ramdas K, Krishnan R, Kumar V. Higher distress relates to poor quality of life in patients with head and neck cancer. International journal of oral and maxillofacial surgery. 2009 Sep 1;38(9):955-9.
Kessler PA, Bloch-Birkholz A, Leher A, Neukam FW, Wiltfang J. Evaluation of quality of life of patients with oral squamous cell carcinoma. Comparison of two treatment protocols in a prospective study. Radiotherapy and Oncology. 2004 Mar 1;70(3):275-82.
Rogers SN, Fisher SE, Woolgar JA. A review of quality of life assessment in oral cancer. International Journal of Oral & Maxillofacial Surgery. 1999 Apr;28(2):99-117.
Bakshi J, Goyal AK, Saini J. Quality of life in oral cancer patients following surgical excision and flap reconstruction. Journal of Maxillofacial and Oral Surgery. 2021 Jan 6:1-6.
Patro SK, Panda NK, Bakshi J, Verma RK, Kumar P, Gaba S, John JR. Quality of life in patients with reconstructions after resections for oral cavity cancers. Indian Journal of Otolaryngology and Head & Neck Surgery. 2019 Oct;71:291-300.
Palitzika D, Tilaveridis I, Lavdaniti M, Vahtsevanos K, Kosintzi A, Antoniades K. Quality of Life in Patients With Tongue Cancer After Surgical Treatment: A 12-Month Prospective Study. Cureus. 2022 Feb 23;14(2).
Carranza ET, Cossío PI, Guisado JM, Aumente EH, Perez JL. Assessment of quality of life in oral cancer. Med Oral Patol Oral Cir Bucal. 2008 Nov 1;13(11):E735-741.
Becker ST, Menzebach M, Küchler T, Hertrampf K, Wenz HJ, Wiltfang J. Quality of life in oral cancer patients–effects of mandible resection and socio-cultural aspects. Journal of Cranio-Maxillofacial Surgery. 2012 Jan 1;40(1):24-7.
Markovic MM, Petrovic M, Latas M, Djordjevic I, Milovanovic S, Jovanovic S. Quality of Life of Patients with Oral Squamous Cell Carcinoma. Iranian Journal of Public Health. 2024 Feb;53(2):414.
van Hinte G, Withagen KP, de Bree R, Speksnijder CM. Neck and shoulder morbidity in patients with oral cancer and clinically negative node neck status: a comparison between the elective neck dissection and sentinel lymph node biopsy strategies. InHealthcare 2022 Dec 16 (Vol. 10, No. 12, p. 2555). MDPI.
Popovski V, Benedetti A, Popovic-Monevska D, Grcev A, Stamatoski A, Zhivadinovik J. Spinal accessory nerve preservation in modified neck dissections: surgical and functional outcomes. Acta Otorhinolaryngologica Italica. 2017 Oct;37(5):368.
Lee SH, Lee JK, Jin SM, Kim JH, Park IS, Chu HR, Ahn HY, Rho YS. Anatomical variations of the spinal accessory nerve and its relevance to level IIb lymph nodes. Otolaryngology--Head and Neck Surgery. 2009 Nov;141(5):639-44.
Kanatas AN, Rogers SN. A national survey of health-related quality of life questionnaires in head and neck oncology. Annals of the Royal College of Surgeons of England. 2004 Jan;86(1):6.
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