Platelet Rich Fibrin :-A Literature Review

Authors

  • Anurag Hasti
  • Ayushi Mishra
  • Tanu Gupta
  • Rashi
  • Rajvi Tayal
  • Manisha Dayma

Keywords:

platelet-rich fibrin, platelets, growth factors, wound healing, bone formation, bone graft, membrane

Abstract

Platelet-rich fibrin (PRF), a second-generation platelet concentrate, has emerged as an increasingly popular option in regenerative medicine. This biological material offers several advantages - it comes from the patient's own body, requires simple preparation steps, is cost-effective, and provides sustained release of growth factors over time, making it superior to conventional platelet concentrates. While researchers have developed various PRF preparation methods that yield different concentrations of growth factors and biomolecules essential for wound healing, there soft tissues. This article examines recent developments in understanding the physiological effects of PRF components and explores innovative approaches to its use. Additionally, it traces the development of platelet concentrates over time and examines the biological characteristics of different PRF preparation techniques

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References

Pavlovic V, Ciric M, Jovanovic V, Trandafilovic M, Stojanovic P. Platelet-rich fibrin: Basics of biological actions and protocol modifications. Open medicine. 2021 Mar 22;16(1):446-54.

AgrawalA M, AgrawalB V. Platelet Rich Fibrin and its Applications in Dentistry-A.

Pietruszka P, Chruścicka I, Duś-Ilnicka I, Paradowska-Stolarz A. Prp and prf—Subgroups and divisions when used in dentistry. Journal of personalized medicine. 2021 Sep 23;11(10):944.

Varshney S, Dwivedi A, Pandey V. Antimicrobial effects of various platelet rich concentrates-vibes from in-vitro studies-a systematic review. Journal of oral biology and craniofacial research. 2019 Oct 1;9(4):299-305.

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Published

2025-09-23

How to Cite

1.
Hasti A, Mishra A, Gupta T, Rashi R, Tayal R, Dayma M. Platelet Rich Fibrin :-A Literature Review. J Neonatal Surg [Internet]. 2025Sep.23 [cited 2025Oct.11];14(28S):1120-3. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/9195

Issue

Vol. 14 No. 28S (2025): Journal of Neonatal Surgery

Section

Original Article

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