Strategies to Prevent Healthcare-Associated Infections: Systematic Review

Authors

  • Majed Sanat Rashed Alharbi
  • Mousa Mulfi Abdullah Almutairi
  • Bader Abaid A Alharbi
  • Raed Jurayyad Saud Alharbi
  • Bader Meatag A Almutairi
  • Hammad Qnaim R Almutairi

DOI:

https://doi.org/10.52783/jns.v14.2397

Keywords:

prevention, hand hygiene, environmental hygiene, surveillance, antibiotic stewardship

Abstract

Healthcare-associated infections (HCAIs) represent a significant public health challenge  and are associated with high burdens of illness and death worldwide. According  to research, healthcare-associated infections (HCAIs) are estimated to affect seven per hundred hospitalized patients in high-income countries and ten in emerging and low-income countries. The increasing antimicrobial resistance among pathogens worse ns because very few new antimicrobial agents have entered the market. This article highlights  different potential approaches to preventing the occurrence of HCAIs. It sets out how hand hygiene has been and continues to be a key preventative measure across the ages. HCAIs can be addressed through several methods, including keeping the hospital environment clean and  enacting antibiotic stewardship programs.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Haque M, McKimm J, Godman B, Abu Bakar M, Martelli M. Initiatives to reduce postoperative surgical site infections of the head and neck cancer surgery with a special emphasis on developing countries. Expert Rev Anticancer Ther. 2019;19(1):81–92. doi:10.1080/14737140.2019.1544497

Cassini A, Plachouras D, Eckmanns T, et al. The burden of six healthcare-associated infections on European population health: estimating incidence-based disability-adjusted life years through a population prevalence-based modeling study. PLoS Med. 2016;13(10):e1002150. doi:10.1371/journal.pmed.1002150

Ricchizzi E, Latour K, Kärki T, et al. Antimicrobial use in European long-term care facilities: results from the third point prevalence survey of healthcare-associated infections and antimicrobial use, 2016 to 2017. Euro Surveill. 2018;23(46):1800394. doi:10.2807/1560-7917.ES.2018.23.46.1800394

Ripabelli G, Salzo A, Mariano A, Sammarco ML, Tamburro M; Collaborative Group for HAIs Point Prevalence Surveys in Molise Region. Healthcare-associated infections point prevalence survey, and antimicrobials use in acute care hospitals (PPS 2016–2017) and long-term care facilities (HALT-3): a comprehensive report of the first experience in Molise Region, Central Italy, and targeted intervention strategies. J Infect Public Health. 2019;12(4):509–515.

Dye C. After 2015: infectious diseases in a new era of health and development. Philos Trans R Soc Lond B Biol Sci. 2014;369 (1645):20130426. doi:10.1098/rstb.2013.0426

Frieden TR. Six components are necessary for effective public health program implementation. Am J Public Health. 2014;104(1):17–22. doi:10.2105/AJPH.2013.301608

Adedeji WA. The treasure is called antibiotics. Ann Ib Postgrad Med. 2016;14(2):56-57.

Bianucci R, Benedict OJ, Fornaciari G, Giuffra V. Quinto Tiberio Angelerio and new measures for controlling plague in 16th-century Alghero, Sardinia. Emerg Infect Dis. 2013;19 (9):1478–1483. doi:10.3201/eid1909.120311

Alfani G, Murphy TE. Plague and lethal epidemics in the pre-industrial world. J Econ Hist. 2017;77(1):314–343. doi:10.1017/S0022050717000092

Institute of Medicine (US) Committee for the Study of the Future of Public Health. The future of public health. Washington (DC): National Academies Press (US); 1988. 3. A History of the Public Health System. Available from: https://www.ncbi.nlm.nih.gov/ books/NBK218224/. Accessed August 20, 2020.

Quinn SC, Kumar S. Health inequalities and infectious disease epidemics: a challenge for global health security. Biosecur Bioterror. 2014;12(5):263–273. doi:10.1089/bsp.2014.0032

Yi Y, Lagniton PNP, Ye S, Li E, Xu RH. COVID-19: what has been learned and to be learned about the novel coronavirus disease. Int J Biol Sci. 2020;16(10):1753–1766. doi:10.7150/ijbs.45134

Esfandiari A, Salari H, Rashidian A, Masoumi Asl H, Rahimi Foroushani A, Akbari Sari A. Eliminating healthcare-associated infections in Iran: a qualitative study to explore stakeholders’ views. Int J Health Policy Manag. 2017;7(1):27–34. doi:10.15171/ijhpm.2017.34

Martin M, Zingg W, Hansen S, et al.; PROHIBIT study group. Public reporting of healthcare-associated infection data in Europe. What are the views of infection prevention opinion leaders? J Hosp Infect. 2013;83(2):94–98. doi:10.1016/j.jhin.2012.10.010

Allegranzi B, Bagheri Nejad S, Combescure C, et al. The burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet. 2011;377 (9761):228–241. doi:10.1016/S0140-6736(10)61458-4

Esfandiari A, Rashidian A, Masoumi Asl H, Rahimi Foroushani A, Salari H, Akbari Sari A. Prevention and control of healthcare-associated infections in Iran: a qualitative study to explore challenges and barriers. Am J Infect Control. 2016;44 (10):1149–1153. doi:10.1016/j.ajic.2016.03.049

Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. Pharm Ther. 2015;40(4):277–283.

Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: a global, multifaceted phenomenon. Pathog Glob Health. 2015;109(7):309–318. doi:10.1179/2047773215Y.0000000030

Paton J, Kresge N, GlaxoSmithKline. Big Pharma is leaving the field of antibiotic research in droves; 2018. Available from: https://www.busi less live.co.za/bd/companies/2018-07-13-big-pharma-is-leaving-the- field-of-antibiotic-research-in-droves/. Accessed February 12, 2019.

Sukkar E Why are there so few antibiotics in the research and development pipeline? The pharmaceutical journal. A Royal Pharmaceutical Society Publication; 2013. Available from: https:// www.pharmaceutical-journal.com/news-and-analysis/features/why- are-there-so-few-antibiotics-in-the-research-and-development- pipeline/11130209.article?firstPass=false. Accessed February 12, 2019.

Mathur P. Prevention of healthcare-associated infections in low- and middle-income countries: the 'bundle approach.' Indian J Med Microbiol. 2018;36(2):155–162. doi:10.4103/ijmm.IJMM_18_152

WHO Guidelines on Hand Hygiene in Health Care: First Global Patient Safety Challenge Clean Care is Safer Care. Geneva: World Health Organization; 2009. 4. Historical perspective on hand hygiene in health care. Available from: https://www.ncbi.nlm.nih. Gov/books/NBK144018/. Accessed February 14, 2019.

Semmelweis I. Etiology, Concept, and Prophylaxis of Childbed Fever. 1st. Carter KC, Madison WI. The University of Wisconsin Press; 1983

Lane HJ, Blum N, Fee E. Oliver Wendell Holmes (1809–1894) and Ignaz Philipp Semmelweis (1818–1865): preventing the transmission of puerperal fever. Am J Public Health. 2010;100 (6):1008–1009. doi:10.2105/AJPH.2009.185363

Labarraque AG. Instructions and Observations Regarding the Use of the Chlorides of Soda and Lime. Porter J, Transed [French]. New Haven, CT: Baldwin and Treadway; 1829.

Lowy EJL, Lilly HA, Bull JP. Disinfection of hands: removal of transient organism. Br Med J. 1964;2(5403):230–233. doi:10.1136/ bmj.2.5403.230

Sanford MD, Widmer AF, Bale MJ, Jones RN, Wenzel RP. Efficient detection and long-term persistence of the carriage of Methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 1994;19:1123–1128. doi:10.1093/clinids/19.6.1123

Rigby R, Pegram A, Woodward S. Hand decontamination in clinical practice: a review of the evidence. Br J Nurs. 2017;26 (8):448–451. doi:10.12968/bjon.2017.26.8.448

Maliwan H. Developing and Evaluating Effective Interventions to Reduce Healthcare-Associated Infection in A Resource-Limited Hospital in Thailand. Ph.D. Thesis. Mahidol Oxford Tropical Medicine Research Unit. The Open University; 2018. Available from: https://oro.open.ac.uk/55283/7/Thesis_Maliwan% 20Hongsuwan%2C%20B6976542.pdf. Accessed February 21, 2019

Larson EL, Cronquist AB, Whittier S, Lai L, Lyle CT, Della Latta P. Differences in skin flora between inpatients and chronically ill patients. Heart Lung. 2000;29:298–305. doi:10.1067/mhl.2000.108324

Downloads

Published

2025-03-20

How to Cite

1.
Rashed Alharbi MS, Abdullah Almutairi MM, A Alharbi BA, Saud Alharbi RJ, A Almutairi BM, R Almutairi HQ. Strategies to Prevent Healthcare-Associated Infections: Systematic Review. J Neonatal Surg [Internet]. 2025Mar.20 [cited 2025Sep.20];14(7S):293-7. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/2397