Preventing Post Phacoemulsification Infection With Intracameral Levofloxacin Administrative
DOI:
https://doi.org/10.52783/jns.v14.2639Keywords:
phacoemulsification, intracameral levofloxacin, infection, prevention, surgeryAbstract
Aim: To determine the efficacy of intracameral levofoxacin to prevent post phacoemulsification (phaco) infection.
Material and methods: 2864 eyes of 2032 patients underwent phacoemulsification. Levofloxacin 0.5% given at the end step of surgery intracamerally. Eye conditions, uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and intraocular pressure (IOP) were observed and recorded.
Results: There is no observed infection event from day one until one month after surgery. UCVA and BCVA were improved (P<0.001) respectively, and IOP was reduced (P<0.001) on one month after surgery.
Conclusion: Intracameral levofloxacin may be effective to prevent post phaco infection. UCVA, BCVA, and IOP were improved following the absence of infection events.
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Allen D, Vasavada A. Cataract and surgery for cataract. BMJ. 2006 Jul 15;333(7559):128-132. doi: 10.1136/bmj.333.7559.128. PMID: 16840470; PMCID: PMC1502210.
Pardianto G, Tassignon MJ. (eds) Innovation in Cataract Surgery. Springer, Singapore. ISBN: 978-981-97-5191-4 (Hard Cover), 978-981-97-5194-5 (Soft Cover), 978-981-97-5192-1 (eBook) https://doi.org/10.1007/978-981-97-5192-1
Chang A, Fridberg A, Kugelberg M. Comparison of phacoemulsification cataract surgery with low versus standard fluidic settings and the impact on postoperative parameters. Eur J Ophthalmol. 2017 Jan 19;27(1):39-44. doi: 10.5301/ejo.5000813. Epub 2016 May 31. PMID: 27312207.
Astbury N, Nyamai LA. Detecting and managing complications in cataract patients. Community Eye Health. 2016;29(94):27-29. PMID: 27833260; PMCID: PMC5100470.
Lapp T, Wacker K, Heinz C, Maier P, Eberwein P, Reinhard T. Cataract Surgery-Indications, Techniques, and Intraocular Lens Selection. Dtsch Arztebl Int. 2023 May 30;120(21):377-386. doi: 10.3238/arztebl.m2023.0028. PMID: 36794457; PMCID: PMC10413970.
Al Mahmood AM, Al-Swailem SA, Behrens A. Clear corneal incision in cataract surgery. Middle East Afr J Ophthalmol. 2014 Jan-Mar;21(1):25-31. doi: 10.4103/0974-9233.124084. PMID: 24669142; PMCID: PMC3959037.
Grzybowski A. Recent developments in cataract surgery. Ann Transl Med. 2020 Nov;8(22):1540. doi: 10.21037/atm-2020-rcs-16. PMID: 33313285; PMCID: PMC7729366.
Shi SL, Yu XN, Cui YL, Zheng SF, Shentu XC. Incidence of endophthalmitis after phacoemulsification cataract surgery: a Meta-analysis. Int J Ophthalmol. 2022 Feb 18;15(2):327-335. doi: 10.18240/ijo.2022.02.20. PMID: 35186695; PMCID: PMC8818473.
Kocak I, Kocak F, Teker B, Aydin A, Kaya F, Baybora H. Evaluation of bacterial contamination rate of the anterior chamber during phacoemulsification surgery using an automated microbial detection system. Int J Ophthalmol. 2014 Aug 18;7(4):686-8. doi: 10.3980/j.issn.2222-3959.2014.04.19. PMID: 25161944; PMCID: PMC4137208.
Espiritu CRG, Bolinao JG. Prophylactic intracameral levofloxacin in cataract surgery - an evaluation of safety. Clin Ophthalmol. 2017 Dec 12;11:2199-2204. doi: 10.2147/OPTH.S144625. PMID: 29276375; PMCID: PMC5731440.
Titiyal JS, Kaur M. Role of intracameral antibiotics in endophthalmitis prophylaxis following-cataract surgery. Indian J Ophthalmol. 2020 May;68(5):688-691. doi: 10.4103/ijo.IJO_195_20. PMID: 32317429; PMCID: PMC7350474.
Pardianto G, Moeloek N, Reveny J, Wage S, Satari I, Sembiring R, Srisamran N. Retinal thickness changes after phacoemulsification. Clin Ophthalmol. 2013;7:2207-14. doi: 10.2147/OPTH.S53223. Epub 2013 Nov 5. PMID: 24235812; PMCID: PMC3821754.
Parmono AF, Pardianto G, Purworini D. Safety of phacoemulsification with gradual hydrodissection on posterior polar cataract. Vision Science and Eye Health Journal, 2024:3(3);51-54 DOI: https://doi.org/10.20473/vsehj.v3i3.2024.51-54
Arshinoff SA, Modabber M. Dose and administration of intracameral moxifloxacin for prophylaxis of postoperative endophthalmitis. J Cataract Refract Surg. 2016 Dec;42(12):1730-1741. doi: 10.1016/j.jcrs.2016.10.017. PMID: 28007104.
Haripriya A, Chang DF, Namburar S, Smita A, Ravindran RD. Efficacy of Intracameral Moxifloxacin Endophthalmitis Prophylaxis at Aravind Eye Hospital. Ophthalmology. 2016 Feb;123(2):302-308. doi: 10.1016/j.ophtha.2015.09.037. Epub 2015 Oct 30. PMID: 26522705.
Ball P. Efficacy and safety of levofloxacin in the context of other contemporary fluoroquinolones: a review. Curr Ther Res Clin Exp. 2003 Nov;64(9):646-61. doi: 10.1016/j.curtheres.2003.11.003. PMID: 24944413; PMCID: PMC4053061.
Pardianto G, editor. The Intraocular Lens Power Calculation. Medan: Anak Sudarti Foundation. 2022.
Silitonga, A.R., Pardianto, G. (2024). Fundamentals of Phaco Innovations: Definitions and Basic Understanding. In: Pardianto, G., Tassignon, MJ. (eds) Innovation in Cataract Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-97-5192-1_2
Zuo C, Long B, Guo X, Chen L, Liu X. Effect of Phacoemulsification on Anterior Chamber Angle in Eyes with Medically Uncontrolled Filtered Primary Angle-Closure Glaucoma. J Ophthalmol. 2020 Apr 21;2020:8720450. doi: 10.1155/2020/8720450. PMID: 32377424; PMCID: PMC7191372.
Wang SY, Azad AD, Lin SC, Hernandez-Boussard T, Pershing S. Intraocular Pressure Changes after Cataract Surgery in Patients with and without Glaucoma: An Informatics-Based Approach. Ophthalmol Glaucoma. 2020 Sep-Oct;3(5):343-349. doi: 10.1016/j.ogla.2020.06.002. Epub 2020 Jun 9. PMID: 32703703; PMCID: PMC7529869.
Pardianto G. Recent awareness and consideration of intraocular pressure fluctuation during eye surgery. J Cataract Refract Surg. 2015 Mar;41(3):695. doi: 10.1016/j.jcrs.2015.01.009. PMID: 25804599.
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