"Evaluating The Antibacterial Efficacy of Avocado Seeds Extract Against Enterococcus Faecalis: An In Vitro Study for Root Canal Irrigation"

Authors

  • Om Prasad Pal
  • Swetha H B
  • Thokala Dhamodaran
  • Kavana M.G
  • Aathees A S
  • Sandhra Johnson

Keywords:

Avocado seeds, Ethanol, Enterococcus faecalis, Herbal irrigant

Abstract

Root canal infections often involve Enterococcus faecalis, a resilient bacterium that can hide within tooth tubules. Traditional root canal irrigants have limitations, prompting research into alternative agents. One such candidate is an ethanol extract from avocado seeds, known for their bioactive compounds. If effective, avocado seed extract could offer a natural solution for combating Enterococcus faecalis during endodontic treatments, benefiting both patients and clinicians seeking improved strategies for root canal therapy..

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References

Nurliza, Cut & Savitri, Wulandari & Dennis, Dennis. (2017). Antibacterial effect of ethanol extract of the avocado seed (Persea Americana Mill.) as an alternative root canal Irrigants against Porphyromonas Gingivalis (In Vitro).

Ghorbanzadeh, A., Fekrazad, R., Bahador, A., Ayar, R., Tabatabai, S., & Asefi, S. (2018). Evaluation of the antibacterial efficacy of various root canal disinfection methods against Enterococcus faecalis biofilm. An ex-vivo study. Photodiagnosis and photodynamic therapy, 24, 44–51.

Nishitha Arun, Sindhu Ramesh, & Anjali Sankar. (2023). Evaluation Of Antibacterial Efficacy Of Carica Papaya Leaf and Seed Extract Against Enterococcus faecalis. Journal of Population Therapeutics and Clinical Pharmacology, 30(14), 19–25.

Anjum V, Ansari SH, Naquvi KJ, Arora P. Physico-Chemical And Phytochemical Evaluation Of Carica Papaya Linn. Unripe Fruits [Internet]. Vol. 4, International Research Journal Of Pharmacy. 2013. p. 101–6.

Mohammadi Z, Shalavi S, Giardino L, Palazzi F, Asgary S. Antibacterial efficacy of chlorhexidine, sodium hypochlorite and etidronate against Enterococcus faecalis biofilm. J Clin Exp Dent. 2016;8(4):e380-e384.

Estrela C, Silva JA, de Alencar AH, Leles CR, Decurcio DA. Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis--a systematic review. J Appl Oral Sci. 2008 Nov-Dec;16(6):364-8.

Goel P, Galhotra V, Makkar S, et al. An In-vitro Study Comparing the Antimicrobial Efficacy of 0.2% Chitosan, 3% Sodium Hypochlorite, 2% Chlorhexidine against Enterococcus faecalis, Alone and in Conjunction with Diode Laser. Int J Clin Pediatr Dent 2022;15(1):109–114.

Rhodes JS. Advanced Endodontics: Clinical Retreatment and Surgery. CRC Press; 2005. 218 p.5. S DPA, Solete P, Jeevanandan G, Syed AA, Almahdi S, Alzhrani M, et al. Effect of Various Irrigant Activation Methods and Its Penetration in the Apical Third of Root Canal-In Vitro Study. Eur J Dent. 2023 Feb;17(1):57–61.

Peter JK, Department of Microbiology and Fermentation Technology, JSBB, SHIATS- Deemed to be University, Naini, UP, et al. Antibacterial Activity of Seed and Leaf Extract of Carica Papaya var. Pusa dwarf Linn [Internet]. Vol. 9, IOSR Journal of Pharmacy and Biological Sciences. 2014. p. 29–37.

Berber VB, Gomes BP, Sena NT, et al. Efficacy of various concentrations of NaOCl and instrumentation techniques in reducing Enterococcus faecalis within root canals and dentinal tubules. Int Endod J 2006;39(1):10–17.

Siddique R, Nivedhitha MS. Effectiveness of rotary and reciprocating systems on microbial reduction: A systematic review. J Conserv Dent. 2019 Mar-Apr;22(2):114–22.

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Published

2025-04-26

How to Cite

1.
Pal OP, H B S, Dhamodaran T, M.G K, A S A, Johnson S. "Evaluating The Antibacterial Efficacy of Avocado Seeds Extract Against Enterococcus Faecalis: An In Vitro Study for Root Canal Irrigation". J Neonatal Surg [Internet]. 2025Apr.26 [cited 2025Oct.20];14(19S):32-7. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/4694

Issue

Vol. 14 No. 19S (2025): Journal of Neonatal Surgery

Section

Original Article

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