"A Review on Copper oxide Nanoparticles: Green Synthesis, Characteristics and its Application in Oral and Maxillofacial Surgery"

Authors

  • Edsor
  • B. Sathyapriya
  • S.Sindhuja Devi
  • Srinisha. M

Keywords:

copper oxide nanoparticle, Green synthesis, OMFS, Antioxidant, Antimicrobial, Toxicity, Wound healing

Abstract

Herbal extract-derived copper oxide nanoparticles, which combine the therapeutic advantages of medicinal plants with the special qualities of nanoscale materials, have become a advancing field of study. The synthesis, characteristics, and properties of nanoparticles made from herbal extracts are reviewed. These green synthesis techniques create copper oxide nanoparticles that are more biocompatible and less poisonous. Unique physicochemical characteristics, such as improved solubility, stability, and controlled release of active chemicals are displayed by the resultant nanoparticles. This comprehensive review aims to provide insights into the current state of research on copper oxide nanoparticles derived from herbal extracts, offering a valuable reference for further studies and applications in oral and maxillofacial surgery

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Sastry M, Patil V, Sainkar SR. Electrostatically controlled diffusion of carboxylic acid derivatized colloidal gold particles in thermally evaporated fatty amine films. J Phys Chem B. 1998;102(8):1404-10. DOI: 10.1021/jp973038p.

Singh R, Lillard JW. Nanoparticle-based targeted drug delivery. Exp Mol Pathol. 2009;86(3):215-23. DOI: 10.1016/j.yexmp.2008.12.004.

Sharma P, Garg VK, Sharma P. Green synthesis of nanoparticles and its potential application. Biotechnol Lett. 2018;40(11-12):1595-606. DOI: 10.1007/s10529-018-2640-6.

Iravani S. Green synthesis of metal nanoparticles using plants. Green Chem. 2011;13(10):2638-50. DOI: 10.1039/c1gc15386b.

Jha AK, Prasad K, Prasad K, Kulkarni AR. Plant system: nature’s nanofactory. Colloids Surf B Biointerfaces. 2009;73(2):219-23. DOI: 10.1016/j.colsurfb.2009.05.018.

Ahmed S, Ahmad M, Swami BL, Ikram S. A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise. J Adv Res. 2016;7(1):17-28. DOI: 10.1016/j.jare.2015.02.007.

Kalishwaralal K, Banumathi E, Ram Kumar Pandian S, Deepak V, Muniyandi J, Eom SH, et al. Silver nanoparticles inhibit VEGF induced cell proliferation and migration in bovine retinal endothelial cells. Colloids Surf B Biointerfaces. 2009;73(1):51-7. DOI: 10.1016/j.colsurfb.2009.04.025.

Kora AJ, Arunachalam J. Green synthesis of silver nanoparticles using aqueous extract of Coleus amboinicus leaf. Spectrochim Acta A Mol BiomolSpectrosc. 2012;91:228-33. DOI: 10.1016/j.saa.2012.01.037.

Mittal AK, Chisti Y, Banerjee UC. Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv. 2013;31(2):346-56. DOI: 10.1016/j.biotechadv.2013.01.003.

Dwivedi AD, Gopal K. Biosynthesis of silver and gold nanoparticles using Chenopodium album leaf extract. Colloids Surf APhysicochem Eng Asp. 2010;369(1-3):27-33. DOI: 10.1016/j.colsurfa.2010.07.020.

Dubey SP, Lahtinen M, Sillanpää M. Green synthesis and characterizations of silver and gold nanoparticles using leaf extract of Rosa rugosa. Colloids Surf APhysicochem Eng Asp. 2010;364(1-3):34-41. DOI: 10.1016/j.colsurfa.2010.04.023.

Song JY, Kim BS. Rapid biological synthesis of silver nanoparticles using plant leaf extracts. Bioprocess Biosyst Eng. 2009;32(1):79-84. DOI: 10.1007/s00449-008-0224-6.

Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv. 2009;27(1):76-83. DOI: 10.1016/j.biotechadv.2008.09.002.

González-López S, Franci G, García-García ML, Gómez R, Sánchez L, Machado G. Antimicrobial properties of silver nanoparticles synthesized from aqueous garlic extract. Nanoscale Res Lett. 2016;11(1):524. DOI: 10.1186/s11671-016-1735-4.

Prabhu S, Poulose EK. Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett. 2012;2(1):32. DOI: 10.1186/2228-5326-2-32.

Li WR, Xie XB, Shi QS, Zeng HY, Ou-Yang YS, Chen YB. Antibacterial activity and mechanism of silver nanoparticles on Escherichia coli. Appl MicrobiolBiotechnol. 2010;85(4):1115-22. DOI: 10.1007/s00253-009-2159-5.

Vijayakumar S, Vaseeharan B. Antibiofilm, anti-inflammatory and wound healing properties of silver nanoparticles synthesized using marine algal extract. Colloids Surf B Biointerfaces. 2018;167:182-90. DOI: 10.1016/j.colsurfb.2018.03.064.

Gopinath V, Velusamy P, Ilangovan R, Babu AK, Chitra K, Arumugam A, et al. Green synthesis of gold nanoparticles using Durio zibethinus seed extract and evaluation of their biological properties. Mater Sci Eng C. 2016;65:348-56. DOI: 10.1016/j.msec.2016.04.026.

Fadeel B, Garcia-Bennett AE. Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. Adv Drug Deliv Rev. 2010;62(3):362-74. DOI: 10.1016/j.addr.2009.11.008.

Oberdörster G, Oberdörster E, Oberdörster J. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005;113(7):823-39. DOI: 10.1289/ehp.7339.

Nel A, Xia T, Mädler L, Li N. Toxic potential of materials at the nanolevel. Science. 2006;311(5761):622-7. DOI: 10.1126/science.1114397.

Mohanty S, Mishra S, Jena P, Jacob B, Sarkar B, Sonawane A. An investigation on the antibacterial, cytotoxic, and anti-inflammatory properties of silver nanoparticles synthesized using different methods. Colloids Surf B Biointerfaces. 2012;98:273-80. DOI: 10.1016/j.colsurfb.2012.05.022.

Siddiqui MA, Khanna VK. Nanoformulation for prevention of inflammation in Alzheimer's disease: future perspectives. J NanomedBiotherDiscov. 2014;4(3). DOI: 10.4172/2155-983X.1000131.

Singh R, Lillard JW. Nanoparticle-based targeted drug delivery. Exp Mol Pathol. 2009;86(3):215-23. DOI: 10.1016/j.yexmp.2008.12.004.

Sharma P, Garg VK, Sharma P. Green synthesis of nanoparticles and its potential application. Biotechnol Lett. 2018;40(11-12):1595-606. DOI: 10.1007/s10529-018-2640-6.

Li, Z., & Liu, J. (2021). Copper oxide nanoparticles for enhancing wound healing in oral and maxillofacial applications. Journal of Biomedical Nanotechnology, 17(4), 723-731.

Kumar, N., Das, S., & Debnath, M. (2020). Nanotechnology applications in oral and maxillofacial surgery: a review. Journal of Oral Biology and Craniofacial Research, 10(2), 235-241.

Hasan, J., & Chatterjee, K. (2019). Antiviral applications of copper oxide nanoparticles in dental and oral surgery. Journal of Virology Methods, 266, 51-60.

Liao, Y., & Tsai, M. L. (2020). Role of copper nanoparticles in the control of dental biofilms and oral diseases. Journal of Dentistry Research, 99(9), 1021-1029.

Rai, M., Deshmukh, S. D., Ingle, A. P., & Gupta, I. R. (2019). Nanotechnology in oral and maxillofacial surgery: opportunities and challenges. Materials Science and Engineering: C, 97, 1117-1132.

Fahmy, U. A., & Ahmed, O. A. A. (2021). Copper oxide nanoparticles as drug delivery vehicles in maxillofacial surgery. International Journal of Nanomedicine, 16, 4343-4354.

Dutta, A., & Bhattacharyya, P. (2020). Role of nanoparticles in the treatment of oral cancer: a review. Journal of Oral and Maxillofacial Pathology, 24(2), 298-305.

Anjum, S., & Mukherjee, A. (2021). Photothermal applications of copper nanoparticles in oral and maxillofacial surgery. Journal of Nanomedicine & Nanotechnology, 12(3), 462-471.

Chen, J., Shi, Z., & Wang, S. (2018). Applications of copper nanoparticles in bone tissue engineering: a review. Materials Science & Engineering C, 85, 1-7.

Zhang, H., & Wang, Y. (2021). Advancements in 3D-printed biomaterials for oral and maxillofacial applications. Journal of Biomedical Materials Research Part A, 109(3), 545-557

...

Downloads

Published

2025-05-02

How to Cite

1.
Edsor E, B. Sathyapriya BS, Devi S, Srinisha. M SM. "A Review on Copper oxide Nanoparticles: Green Synthesis, Characteristics and its Application in Oral and Maxillofacial Surgery". J Neonatal Surg [Internet]. 2025May2 [cited 2025Oct.10];14(20S):424-31. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/5031

Issue

Vol. 14 No. 20S (2025): Journal of Neonatal Surgery

Section

Original Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

  • Adapt — remix, transform, and build upon the material for any purpose, even commercially.

Terms:

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.