A Dosimetric Comparison of IMRT Vsvmat Techniques in Single Vocal Cord Irradiation in The Treatment of T1an0 Glottic Cancer

Authors

  • Mohamed Mortada Elsharief
  • Ashraf Hamed Hassouna
  • Tarek Shouman
  • Amr Elbadraway
  • Abdelrahman Mosallam
  • Sherweif Mohamed Abdelfatah

Keywords:

Single Vocal Cord Irradiation, T1a Glottic Cancer, IMRT, VMAT, Dosimetric Comparison

Abstract

This dosimetric study compares intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques in single vocal cord irradiation (SVCI) for patients with T1aN0 glottic cancer. Historically, early glottic carcinoma has been managed with large-field radiotherapy, often exposing surrounding healthy tissues to unnecessary radiation and increasing the risk of complications. In contrast, SVCI, inspired by the precision of surgical laser excision, targets only the affected vocal cord, minimizing radiation exposure to adjacent structures. Ten patients underwent CT simulation and treatment planning with both 7-field IMRT and single-arc VMAT. Dose-volume histogram analyses were performed to evaluate planning target volume (PTV) coverage, homogeneity index (HI), conformity index (CI), and dose exposure to organs at risk (OARs). Results demonstrated comparable PTV coverage between IMRT and VMAT, with VMAT showing statistically superior HI and CI. No significant differences were observed in radiation doses delivered to critical OARs including the contralateral vocal cord, pharyngeal constrictor muscles, thyroid gland, carotid arteries, and spinal cord. These findings affirm the feasibility of SVCI using either technique, with VMAT offering dosimetric advantages in homogeneity and conformity. This study supports the use of advanced radiotherapy techniques to achieve effective and safer treatment of early-stage glottic cancer.

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Published

2025-05-22

How to Cite

1.
Mortada Elsharief M, Hassouna AH, Shouman T, Elbadraway A, Mosallam A, Abdelfatah SM. A Dosimetric Comparison of IMRT Vsvmat Techniques in Single Vocal Cord Irradiation in The Treatment of T1an0 Glottic Cancer. J Neonatal Surg [Internet]. 2025May22 [cited 2025Sep.11];14(26S):534-7. Available from: https://www.jneonatalsurg.com/index.php/jns/article/view/6322

Issue

Vol. 14 No. 26S (2025): Journal of Neonatal Surgery

Section

Original Article

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