Unveiling The Silent Giant-A Case Report on Placental Chorioangioma
Keywords:
N\AAbstract
Placental chorioangioma, a rare benign vascular tumor of the placenta, is the most common nontrophoblastic placental tumor. While small lesions are usually asymptomatic, larger lesions (≥4 cm) are associated with significant maternal and fetal complications, including polyhydramnios, fetal anemia, and hydrops fetalis. This case report details a 24-year-old second gravida who presented at 32 weeks of gestation with a 4.8 × 3.2 cm hyperechoic placental lesion identified on ultrasound, suggestive of chorioangioma, accompanied by polyhydramnios (AFI 22 cm). MRI confirmed the diagnosis, revealing a 5.5 × 4.4 cm intraplacental lesion near the fetal surface without myometrial invasion. The patient remained asymptomatic and was managed conservatively with regular follow-up and fetal surveillance. Steroid cover was administered at 32 weeks to promote fetal lung maturity. At 38 weeks, an elective cesarean section was performed, resulting in the delivery of a healthy 2.85 kg female neonate. Placental examination revealed a 5 × 4 cm mass on the fetal surface, confirmed histopathologically as a benign vascular neoplasm composed of capillary-sized blood vessels. Both mother and neonate had uneventful recoveries. This case highlights the importance of advanced imaging, vigilant antenatal monitoring, and multidisciplinary care in achieving favorable outcomes in pregnancies complicated by placental chorioangiomas.
Downloads
References
Hosseinzadeh P, Javadian P, Espinoza J, et al. Prenatal Therapy of Large Placental Chorioangiomas: Case Report and Review of the Literature. DOI:10.1055/s-0035-1558829. Published August 3, 2015.
Eldar-Geva T, Hochner-Celnikier D, Ariel I, et al. Fetal high-output cardiac failure and acute hydramnios caused by large placental chorioangioma: Case report. BJOG. 1988;95(11):1200-1203. DOI:10.1111/j.1471-0528.1988.tb06801.x.
Akercan F, Seyfettinoğlu S, Zeybek B, et al. High-output cardiac failure in a fetus with thanatophoric dysplasia associated with large placental chorioangioma: Case report. J Clin Ultrasound. 2011;39(6):364-366. DOI:10.1002/jcu.20865.
Sepúlveda W, Wong AE, Herrera L, et al. Endoscopic laser coagulation of feeding vessels in large placental chorioangiomas: Report of three cases and review of invasive treatment options. Prenat Diagn. 2009;29(1):71-77. DOI:10.1002/pd.2197.
Montán S, Anandakumar C, Joseph R, et al. Fetal and Neonatal Haemodilution Associated with Multiple Placental Chorioangioma: Case Report. J Obstet Gynaecol Res. 1996;22(1):27-30. DOI:10.1111/j.1447-0756.1996.tb00934.x.
Cvetanovska E, Colov NP, Kahn R. Chorioangioma of the placenta associated with benign multiple neonatal hemangiomatosis. Acta Obstet Gynecol Scand. 2006;85(2):235-239. DOI:10.1080/00016340500486768.
D’Antonio F, Bhide A. Ultrasound in placental disorders. Best Pract Res Clin Obstet Gynaecol. 2014;28(3):429-442. DOI:10.1016/j.bpobgyn.2014.01.001.
Fan M, Skupski DW. Placental chorioangioma: literature review. J Perinat Med. 2013;41(6):553-560. DOI:10.1515/jpm-2013-0170.
Sudhakaran N, Sothinathan U, Patel SB. Best practice guidelines: Fetal surgery. Early Hum Dev. 2011;87(12):743-747. DOI:10.1016/j.earlhumdev.2011.11.006.
Gray DL, Crane JP. Sonographic detection of placental tumors. J Clin Ultrasound. 1984;12(8):445-448. DOI:10.1002/jcu.1870120803.
Sepúlveda W, Avila C, Alcalde JL. Fetal Doppler in placental chorioangioma: A report of 11 cases. Ultrasound Obstet Gynecol. 2003;22(5):437-442. DOI:10.1002/uog.911.
Bruch JF, Baud C, Tack I, et al. Ultrasound and magnetic resonance imaging in the prenatal diagnosis of placental chorioangioma. J Radiol. 2004;85(10):1796-1800. DOI:10.1016/S0221-0363(04)97715-3.
Khong TY. Placental vascular tumors. Clin Pathol. 2001;54(3):176-182. DOI:10.1136/jcp.54.3.176.
Ashrafganjooei T, Amiri Z, Amiri SS. Large placental chorioangioma: Prenatal sonographic findings and perinatal outcomes. Iran J Reprod Med. 2013;11(12):1033-1036.
Jauniaux E, Greenough A. Placental vascular anomalies. Best Pract Res Clin Obstet Gynaecol. 2007;21(3):685-696. DOI:10.1016/j.bpobgyn.2006.12.005.
Zalud I, Pate B. Placental chorioangioma. Semin Perinatol. 2015;39(1):7-16. DOI:10.1053/j.semperi.2014.10.007
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
Terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.