Reoperation Versus Radiosurgery in Cases of Recurrent Secreting Pituitary Adenoma
Keywords:
Pituitary adenomas, Stereotactic irradiation, Gamma Knife radiosurgery (GKRS)Abstract
Background: Pituitary adenomas accounted for nearly 10% to 15% of all surgically treated primary central nervous system tumours. Prolactinoma is the most common subtype of Pituitary adenomas. The majority of pituitary adenomas are sporadic tumours.
Aim and Objectives: To identify the best option for treatment of recurrent secreting pituitary adenoma and evaluate the risks and advantages of each option.
Patients and Methods: This Cross-sectional analytic study enrolled 52 patients with secreting pituitary adenomas that were previously operated upon by transsphenoidal surgery collected from neurosurgery department in Kasr Alainy Hospitals and the international medical center.
Results: There was a statistically significant difference between Gamma knife and Reoperation regarding need to medical treatment and time to hormonal control. There was no statistically significant difference between Gamma knife and Reoperation regarding age, sex, the type of secreting adenomas, size of the adenoma, the cavernous sinus invasion, mild complications, Growth control and Hormonal control.
Conclusion: Reoperation and Stereotactic irradiation by gamma knife radiosurgery are safe and effective treatment modality for patients with recurrent secreting pituitary adenomas after unsuccessful surgery or after recurrence.
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