Comparative Analysis Of Lipid Profiles In Metabolic Syndrome Patients Before And After Lifestyle Intervention
DOI:
https://doi.org/10.63682/jns.v14i32S.9204Keywords:
Metabolic Syndrome, Lipid Profile, Lifestyle Intervention, Cardiovascular HealthAbstract
Background: Metabolic Syndrome (Mets) is a set of diseases, such as high blood pressure, high blood sugar, too much body fat around the waist and irregular cholesterol levels, which put a person at risk of heart disease, stroke, and diabetes. Change in lifestyle is recommended to increase lipid profiles and decrease the risk of cardiovascular diseases.
Purposes: To determine effects of lifestyle interventions on lipid profiles in MetS patients, with emphasis on changes in cholesterol, triglycerides and HDL levels.
Study design: A prospective cohort study.
Place and duration of study: Department of Biochemistry; Fazaia Medical College (FMC); Islamabad. Jan 2024 to July, 2024
Methods: The study was a prospective cohort study of patients with MetS who had lipid profile assessments at baseline and after a 12-week lifestyle intervention (dietary changes, physical activity, and behavior modification). Lipid profile was analyzed in blood samples collected at baseline and after the intervention.
Results: The Mean age was 28.2 years (+- 10.4 years). The total cholesterol, LDL cholesterol and triglycerides were significantly decreased after the intervention (p=0.02, p=0.03 and p=0.01, respectively). There was a 8% HDL cholesterol increase (p=0.04), which shows the success of lifestyle changes in enhancing lipid profiles.
Conclusion: Lifestyle interventions were found to significantly improve lipid profiles in MetS patients, and making dietary and physical activity changes is a way to adequately address cardiovascular risk factors..
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